Capsaicin reduces the metastatic burden in the transgenic adenocarcinoma of the mouse prostate model

scientific article published on 5 June 2015

Capsaicin reduces the metastatic burden in the transgenic adenocarcinoma of the mouse prostate model is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PROS.23013
P698PubMed publication ID26047020

P50authorHans AdomatQ47015138
Laurence KlotzQ83824697
P2093author name stringNeil E Fleshner
Vasundara Venkateswaran
Linda M Sugar
Toshihiro Yamamoto
Hans Adomat
Natalie A Venier
P2860cites workCapsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stressQ39486294
Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells.Q39594387
Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cellsQ39908354
In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathwayQ39918605
Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin.Q40336717
Studies of the toxicological potential of capsinoids XIV: a 26-week gavage toxicity study of dihydrocapsiate in ratsQ43100962
Studies of the toxicological potential of capsinoids, XII: pharmacokinetic study of capsinoid-containing CH-19 Sweet extract in ratsQ43100967
Studies of the toxicological potential of capsinoids, XI: pharmacokinetic and tissue distribution study of 14C-dihydrocapsiate and metabolites in ratsQ43100971
Predictive value of decreased p27Kip1 protein expression for the recurrence-free and long-term survival of prostate cancer patientsQ43201975
Antioxidants block prostate cancer in lady transgenic miceQ45020415
Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cellsQ46110803
Capsaicin inhibits proliferation of endometriotic cells in vitroQ46662292
The impact of diet and micronutrient supplements on the expression of neuroendocrine markers in murine Lady transgenic prostateQ46812881
Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model.Q51075713
A combination of micronutrients is beneficial in reducing the incidence of prostate cancer and increasing survival in the Lady transgenic model.Q53397807
Correlation of three immunohistochemically detected markers of neuroendocrine differentiation with clinical predictors of disease progression in prostate cancerQ30856653
Extracts from Epilobium sp. herbs, their components and gut microbiota metabolites of Epilobium ellagitannins, urolithins, inhibit hormone-dependent prostate cancer cells-(LNCaP) proliferation and PSA secretion.Q34597708
Apoptosis by dietary agents for prevention and treatment of prostate cancerQ34614042
Capsaicin treatment attenuates cholangiocarcinoma carcinogenesisQ35153098
Origin of androgen-insensitive poorly differentiated tumors in the transgenic adenocarcinoma of mouse prostate modelQ36143611
Molecular regulation of androgen action in prostate cancerQ36414626
p27(Kip1) V109G polymorphism and cancer risk: a systematic review and meta-analysisQ36451110
Neuroendocrine differentiation in prostate cancerQ36537698
Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processesQ36665729
Androgen receptor structural and functional elements: role and regulation in prostate cancerQ36884596
The interactions of dietary tomato powder and soy germ on prostate carcinogenesis in the TRAMP model.Q36924955
Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathwayQ37185060
AKR1C3 as a target in castrate resistant prostate cancerQ37248854
Glucuronidation does not suppress the estrogenic activity of quercetin in yeast and human breast cancer cell model systemsQ39013083
P433issue12
P921main subjectadenocarcinomaQ356033
P304page(s)1300-1311
P577publication date2015-06-05
P1433published inThe ProstateQ7758608
P1476titleCapsaicin reduces the metastatic burden in the transgenic adenocarcinoma of the mouse prostate model
P478volume75

Reverse relations

cites work (P2860)
Q91831741An updated review on molecular mechanisms underlying the anticancer effects of capsaicin
Q38988562Capsaicin and Its Role in Chronic Diseases.
Q52677331Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin.
Q47353175Capsaicin inhibits the metastasis of human papillary thyroid carcinoma BCPAP cells through the modulation of the TRPV1 channel
Q33566628Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer
Q47647286Chronic diseases, inflammation, and spices: how are they linked?
Q26741831Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases
Q90460347Modified Citrus Pectin as a Potential Sensitizer for Radiotherapy in Prostate Cancer
Q26770555Natural Products for Chemoprevention of Breast Cancer
Q38770019Non-pungent long chain capsaicin-analogs arvanil and olvanil display better anti-invasive activity than capsaicin in human small cell lung cancers
Q26741169Spices for Prevention and Treatment of Cancers

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