Programmed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system.

scientific article

Programmed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/1873-3468.12298
P932PMC publication ID4983237
P698PubMed publication ID27404003

P50authorClaude DesplanQ17465894
P2093author name stringNikolaos Konstantinides
Filipe Pinto-Teixeira
P2860cites workbantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in DrosophilaQ28131827
Homeobox genes and axial patterningQ28181571
fruitless splicing specifies male courtship behavior in DrosophilaQ28254606
Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila developmentQ28259235
Segment-specific prevention of pioneer neuron apoptosis by cell-autonomous, postmitotic Hox gene activityQ28292644
Late-stage neuronal progenitors in the retina are radial Müller glia that function as retinal stem cellsQ28307694
A gene complex controlling segmentation in DrosophilaQ29547506
Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolutionQ30484747
Single cell cultures of Drosophila neuroectodermal and mesectodermal central nervous system progenitors reveal different degrees of developmental autonomyQ30489953
Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cellsQ30492732
Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell deathQ30504143
Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast.Q40800541
Gene expression profiles uncover individual identities of gnathal neuroblasts and serial homologies in the embryonic CNS of DrosophilaQ40858699
The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE.Q40986587
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signalingQ40995001
drICE is an essential caspase required for apoptotic activity in Drosophila cellsQ41006986
Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs).Q41011027
Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.Q41228922
Neural stem cell progeny regulate stem cell death in a Notch and Hox dependent manner.Q41244745
Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brainQ41575899
Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.Q41731870
Drosophila p53 binds a damage response element at the reaper locusQ41731875
Control of Drosophila Type I and Type II central brain neuroblast proliferation by bantam microRNAQ41764581
Nutrition-responsive glia control exit of neural stem cells from quiescence.Q41788576
Wnt/β-catenin-signaling and the formation of Müller glia-derived progenitors in the chick retinaQ41886698
Steroid-triggered, cell-autonomous death of a Drosophila motoneuron during metamorphosisQ41889711
Abdominal-B and caudal inhibit the formation of specific neuroblasts in the Drosophila tail regionQ41920441
Role of Notch signaling in establishing the hemilineages of secondary neurons in Drosophila melanogasterQ41940104
Single-cell mapping of neural and glial gene expression in the developing Drosophila CNS midline cellsQ42124977
Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activityQ42272663
Drosophila grim induces apoptosis in mammalian cells.Q42662756
Coordinated expression of cell death genes regulates neuroblast apoptosisQ42730926
Segment-specific generation of Drosophila Capability neuropeptide neurons by multi-faceted Hox cues.Q42734069
Temporal patterning of neuroblasts controls Notch-mediated cell survival through regulation of Hid or ReaperQ42859873
Transient nuclear Prospero induces neural progenitor quiescence.Q42965733
A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in DrosophilaQ43814873
reaper is required for neuroblast apoptosis during Drosophila developmentQ43906921
Embryonic development of axon pathways in the Drosophila CNS. I. A glial scaffold appears before the first growth conesQ44044793
The regulation of apoptosis by Numb/Notch signaling in the serotonin lineage of DrosophilaQ44521196
Drosophila neuroblast 7-3 cell lineage: a model system for studying programmed cell death, Notch/Numb signaling, and sequential specification of ganglion mother cell identityQ45184362
Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogasterQ45300018
Mechanisms of postecdysis-associated programmed cell death of peptidergic neurons in Drosophila melanogaster.Q45343686
The embryonic development of the Drosophila visual systemQ46181274
Neuroblast lineage identification and lineage-specific Hox gene action during postembryonic development of the subesophageal ganglion in the Drosophila central brainQ46381278
The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis.Q46695412
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell deathQ46725238
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanismsQ46902175
A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradationQ47069979
Drosophila Grainyhead specifies late programmes of neural proliferation by regulating the mitotic activity and Hox-dependent apoptosis of neuroblasts.Q47070109
Cell killing by the Drosophila gene reaperQ47070113
Ras promotes cell survival in Drosophila by downregulating hid expressionQ47070193
A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis.Q47070315
Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of DrosophilaQ47070532
Lineage-specific cell death in postembryonic brain development of DrosophilaQ47070574
The head involution defective gene of Drosophila melanogaster functions in programmed cell deathQ47070937
Neuroblast entry into quiescence is regulated intrinsically by the combined action of spatial Hox proteins and temporal identity factorsQ47070976
Fruitless specifies sexually dimorphic neural circuitry in the Drosophila brainQ47071155
Deterin, a new inhibitor of apoptosis from Drosophila melanogasterQ47071315
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.Q47071366
The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.Q47071492
DCP-1, a Drosophila cell death protease essential for developmentQ47071648
Characterization of the Drosophila caspase, DAMM.Q47072274
A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosisQ47072639
The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of Drosophila.Q47072648
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progenyQ47072696
Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in DrosophilaQ47072806
Molecular markers for identified neuroblasts in the developing brain of DrosophilaQ47791465
Homeotic regulation of segment-specific differences in neuroblast numbers and proliferation in the Drosophila central nervous systemQ47890948
Magnetic pioneers net Nobel for putting medicine in the pictureQ48354459
Programmed cell death during Drosophila embryogenesis.Q48381720
Genetic control of programmed cell death in DrosophilaQ38468332
Apoptosis in Drosophila: which role for mitochondria?Q38672394
Lineage mapping identifies molecular and architectural similarities between the larval and adult Drosophila central nervous systemQ39425120
The embryonic central nervous system lineages of Drosophila melanogaster. II. Neuroblast lineages derived from the dorsal part of the neuroectoderm.Q39453065
Embryonic development of the Drosophila brain. I. Pattern of pioneer tractsQ39480815
Stage-specific inductive signals in the Drosophila neuroectoderm control the temporal sequence of neuroblast specificationQ39578792
From the Eye to the Brain: Development of the Drosophila Visual SystemQ39579593
Hunchback is required for the specification of the early sublineage of neuroblast 7-3 in the Drosophila central nervous systemQ39594845
Patterns of cell division and cell movement in the formation of the imaginal nervous system in Drosophila melanogasterQ39613433
Early development of the Drosophila brain: III. The pattern of neuropile founder tracts during the larval periodQ39638761
Identification and cell lineage of individual neural precursors in the Drosophila CNS.Q40386760
The Drosophila caspase DRONC is regulated by DIAP1Q40387067
Glia-derived neurons are required for sex-specific learning in C. elegansQ40429780
Drosophila sickle is a novel grim-reaper cell death activatorQ40753998
STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2.Q40781431
A region-specific neurogenesis mode requires migratory progenitors in the Drosophila visual system.Q30621052
Early development of the Drosophila mushroom body: the roles of eyeless and dachshund.Q33180723
Caspase-independent cell engulfment mirrors cell death pattern in Drosophila embryosQ33193772
Postmitotic specification of Drosophila insulinergic neurons from pioneer neuronsQ33323448
Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brainQ33552370
Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cuesQ33582048
A complete developmental sequence of a Drosophila neuronal lineage as revealed by twin-spot MARCM.Q33680091
Segment polarity genes in neuroblast formation and identity specification during Drosophila neurogenesisQ33685701
At the nexus between pattern formation and cell-type specification: the generation of individual neuroblast fates in the Drosophila embryonic central nervous systemQ33750226
Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in DrosophilaQ33821327
Reaper-induced apoptosis in a vertebrate systemQ33887900
Metamorphosis in drosophila and other insects: the fate of neurons throughout the stagesQ33924863
Regulation and execution of apoptosis during Drosophila developmentQ33924995
Cytogenetic Analysis of Chromosome 3 in DROSOPHILA MELANOGASTER: The Homoeotic Gene Complex in Polytene Chromosome Interval 84a-B.Q33994021
Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobeQ34080619
GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathwayQ34089594
sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory proteinQ34111911
Molecular mechanisms of cell death and phagocytosis in DrosophilaQ34119236
Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogasterQ34166641
The pattern of neuroblast formation, mitotic domains and proneural gene expression during early brain development in DrosophilaQ34210177
Ecdysteroid titers during pupal and adult development in Drosophila melanogasterQ34270577
The glial identity of neural stem cellsQ34272912
Embryogenesis of an insect nervous system II: a second class of neuron precursor cells and the origin of the intersegmental connectivesQ34283161
Programmed cell death in the Drosophila central nervous system midline.Q34297268
Regulation of neuroblast competence: multiple temporal identity factors specify distinct neuronal fates within a single early competence windowQ34360241
grim, a novel cell death gene in DrosophilaQ34387981
Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryoQ34453464
Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cellsQ34586479
The bantam gene regulates Drosophila growthQ34615713
Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genesQ35049806
Pdm and Castor specify late-born motor neuron identity in the NB7-1 lineageQ35052579
Genetic control of Drosophila nerve cord developmentQ35068969
DRONC, an ecdysone-inducible Drosophila caspaseQ35124238
Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila.Q35135150
Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesisQ35185485
Bridging the gap between postembryonic cell lineages and identified embryonic neuroblasts in the ventral nerve cord of Drosophila melanogasterQ35453312
Programmed neuronal death in insect developmentQ35615497
Role of mitochondrial remodeling in programmed cell death in Drosophila melanogasterQ35830140
Retinal stem cells and regenerationQ35959809
Brainy but not too brainy: starting and stopping neuroblast divisions in Drosophila.Q35996908
Genetic control of programmed cell death in Drosophila melanogasterQ36083631
Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm).Q36110341
How mitochondria fuseQ36173518
Segmental organisation of the tail region in the embryo of Drosophila melanogaster : A blastoderm fate map of the cuticle structures of the larval tail regionQ36311943
The proapoptotic function of Drosophila Hid is conserved in mammalian cellsQ36333384
Transcriptional selectors, masters, and combinatorial codes: regulatory principles of neural subtype specificationQ36354585
Patterns of growth and tract formation during the early development of secondary lineages in the Drosophila larval brainQ36464011
Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobeQ36552024
miRNAs and apoptosis: RNAs to die for.Q36617814
Essential role of grim-led programmed cell death for the establishment of corazonin-producing peptidergic nervous system during embryogenesis and metamorphosis in Drosophila melanogasterQ36702308
Insights into neural stem cell biology from flies.Q36740046
Protection of neuronal diversity at the expense of neuronal numbers during nutrient restriction in the Drosophila visual systemQ36742504
Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cellsQ36766071
Dual role for Hox genes and Hox co-factors in conferring leg motoneuron survival and identity in DrosophilaQ36783144
Temporal patterning of Drosophila medulla neuroblasts controls neural fatesQ36983945
Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in DrosophilaQ37003765
Striatal astrocytes transdifferentiate into functional mature neurons following ischemic brain injuryQ37275582
Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neuronsQ37313845
By design or by chance: cell death during Drosophila embryogenesisQ37494540
Inhibitor of apoptosis proteins in Drosophila: gatekeepers of deathQ37507761
Combinatorial temporal patterning in progenitors expands neural diversityQ37616445
In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease modelQ37668698
Keeping the CNS clear: glial phagocytic functions in DrosophilaQ37817075
Nutrient control of neural stem cells.Q37935308
Temporal patterning of neural progenitors in DrosophilaQ38130393
Temporal fate specification and neural progenitor competence during developmentQ38176634
Intrinsically different retinal progenitor cells produce specific types of progenyQ38237263
Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and functionQ38354320
Ecdysone-dependent and ecdysone-independent programmed cell death in the developing optic lobe of Drosophila.Q50775789
Commitment of CNS progenitors along the dorsoventral axis of Drosophila neuroectoderm.Q51121956
Commitment of abdominal neuroblasts in Drosophila to a male or female fate is dependent on genes of the sex-determining hierarchy.Q51152304
Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of D. melanogaster.Q51167386
Spatio-temporal pattern of programmed cell death in the developing Drosophila optic lobe.Q51782428
Hox Genes and Brain Development in DrosophilaQ51901157
Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in theDrosophilaoptic lobeQ51901613
Neuronal subtype specification within a lineage by opposing temporal feed-forward loops.Q51921622
Antagonistic roles for Ultrabithorax and Antennapedia in regulating segment-specific apoptosis of differentiated motoneurons in the Drosophila embryonic central nervous system.Q51949094
Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila.Q51956127
Mitochondrial disruption in Drosophila apoptosis.Q51986515
Programmed cell death in the embryonic central nervous system of Drosophila melanogaster.Q51999467
Programmed cell death mechanisms of identifiable peptidergic neurons in Drosophila melanogaster.Q52018925
Regulation of post-embryonic neuroblasts by Drosophila Grainyhead.Q52034682
Programmed transformations in neuroblast gene expression during Drosophila CNS lineage development.Q52165191
Glia maintain follower neuron survival during Drosophila CNS development.Q52172312
Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes.Q52181655
Runt determines cell fates in the Drosophila embryonic CNS.Q52186961
Steroid regulated programmed cell death during Drosophila metamorphosis.Q52191726
Genes that induce apoptosis: transcriptional regulation in identified, doomed neurons of the Drosophila CNS.Q52192330
The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm.Q52199402
Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous systemQ52441096
The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster.Q52447099
Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster.Q52448881
Macrophages and glia participate in the removal of apoptotic neurons from the Drosophila embryonic nervous system.Q52536008
A common precursor for glia and neurons in the embryonic CNS of Drosophila gives rise to segment-specific lineage variants.Q52542719
Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform.Q52544663
Targeted neuronal ablation: the role of pioneer neurons in guidance and fasciculation in the CNS of Drosophila.Q52558902
Origin and differentiation of supernumerary midline glia in Drosophila embryos deficient for apoptosis.Q52559619
Genetic and hormonal regulation of the death of peptidergic neurons in the Drosophila central nervous system.Q52568949
Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets.Q52573588
Dynamic mitochondria.Q52574314
The Drosophila neuregulin vein maintains glial survival during axon guidance in the CNS.Q52592496
Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling.Q52594202
Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.Q52652438
Multiple roles for apoptosis facilitating condensation of the Drosophila ventral nerve cord.Q52688362
Multiple roles for Hox genes in segment-specific shaping of CNS lineages.Q52695605
Genetic mechanisms of early neurogenesis in Drosophila melanogasterQ72448831
Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanismsQ74506568
Early neurogenesis in wild-typeDrosophila melanogasterQ89559828
Regulation of neuroblast competence in DrosophilaQ95806314
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
DrosophilaQ312154
P304page(s)2435-2453
P577publication date2016-07-28
P1433published inFEBS LettersQ1388051
P1476titleProgrammed cell death acts at different stages of Drosophila neurodevelopment to shape the central nervous system
P478volume590