Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer.

scientific article

Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JURO.2015.02.2918
P8608Fatcat IDrelease_h4hr2dn23jg4hadmbdnmhqbee4
P932PMC publication ID6371809
P698PubMed publication ID25748177

P2093author name stringGang Li
Song Wang
Lin Du
Hanwei Zhang
Arnold I Chin
Elizabeth Peek
David R Li
P2860cites workIdentification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cellsQ24657020
Cancer statistics, 2013Q27860762
Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III studyQ28139358
Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosisQ28277806
Comprehensive molecular characterization of urothelial bladder carcinomaQ28306864
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancerQ29617772
Vorinostat in solid and hematologic malignanciesQ33385544
Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapyQ33572016
Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cellsQ33919809
Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cellsQ34600254
Inhibitory effect of valproic acid on bladder cancer in combination with chemotherapeutic agents in vitro and in vivoQ35030146
Expression of histone deacetylases 1, 2 and 3 in urothelial bladder cancerQ35119480
Three differentiation states risk-stratify bladder cancer into distinct subtypesQ35750975
The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivoQ36178061
HDAC family: What are the cancer relevant targets?Q37281991
Molecular mechanisms of cisplatin resistance in bladder cancer.Q37982453
Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancerQ39395076
HDAC inhibition delays cell cycle progression of human bladder cancer cells in vitroQ39493944
Experimental study on inhibitory effects of histone deacetylase inhibitor MS-275 and TSA on bladder cancer cellsQ39889318
Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancerQ40236236
Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemiaQ41769694
A Phase II Clinical Trial of Oral Valproic Acid in Patients with Castration-Resistant Prostate Cancers Using an Intensive Biomarker Sampling StrategyQ41863259
HDACs link the DNA damage response, processing of double-strand breaks and autophagyQ41979339
Stromal modulation of bladder cancer-initiating cells in a subcutaneous tumor model.Q42379859
Inhibition of bladder tumour growth by histone deacetylase inhibitorQ43291800
Romidepsin for cutaneous T-cell lymphomaQ83996070
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcisplatinQ412415
P304page(s)547-555
P577publication date2015-03-03
P1433published inJournal of UrologyQ15709979
P1476titleSynergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer
P478volume194

Reverse relations

cites work (P2860)
Q47584543A phase 1 trial of the HDAC inhibitor AR-42 in patients with multiple myeloma and T- and B-cell lymphomas
Q92460583AR-42: A Pan-HDAC Inhibitor with Antitumor and Antiangiogenic Activities in Esophageal Squamous Cell Carcinoma
Q57452829CD24 regulates cancer stem cell (CSC)-like traits and a panel of CSC-related molecules serves as a non-invasive urinary biomarker for the detection of bladder cancer
Q64121548Histone Deacetylase Inhibitor, Trichostatin A, Synergistically Enhances Paclitaxel-Induced Cytotoxicity in Urothelial Carcinoma Cells by Suppressing the ERK Pathway
Q90221601Histone deacetylase inhibitor AR-42 inhibits breast cancer cell growth and demonstrates a synergistic effect in combination with 5-FU
Q38572855Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review
Q28076041Molecular targets in urothelial cancer: detection, treatment, and animal models of bladder cancer
Q40084337Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways
Q57028508Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma

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