c-Src function is necessary and sufficient for triggering microglial cell activation

scientific article

c-Src function is necessary and sufficient for triggering microglial cell activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/GLIA.22767
P8608Fatcat IDrelease_nliddwa4azbrpjxhx73veuqboa
P698PubMed publication ID25421817
P5875ResearchGate publication ID267844005

P50authorErick C. LoiolaQ37368137
António Francisco AmbrósioQ38326805
Ana R. SantiagoQ41863329
Joao RelvasQ43115278
Renato SocodatoQ52675958
Camila C PortugalQ56526128
Roberto Paes-de-CarvalhoQ56526130
Ivan DomithQ56526140
Tânia MartinsQ56526201
P2093author name stringNádia A Oliveira
Vivian S M Coreixas
P2860cites workFunctional role of c-Src in IL-1-induced NF-kappa B activation: c-Src is a component of the IKK complexQ24297449
TLR signaling pathwaysQ24570127
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivoQ27860578
Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behaviorQ28116742
Physiology of microgliaQ29547414
Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.Q30484062
The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activationQ33580106
Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural viewsQ33797129
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensorsQ33842919
Engineered allosteric activation of kinases in living cellsQ33987463
Selected glimpses into the activation and function of Src kinaseQ34103644
Constitutive activation of Src family kinases in mouse embryos that lack Csk.Q34366689
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) protein expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB).Q35763283
Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanismQ35803328
Src in synaptic transmission and plasticityQ35920905
Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and LynQ36377155
The role of Src kinase in macrophage-mediated inflammatory responsesQ36418104
Quantitating the subtleties of microglial morphology with fractal analysisQ36572876
Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signallingQ36804453
Microglial activation and its implications in the brain diseases.Q36822646
Debris clearance by microglia: an essential link between degeneration and regeneration.Q37092476
The absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murinaQ37191294
Tyrosine kinases and inflammatory signallingQ37387459
Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talkQ37808572
Regulation of the SRC family kinases by Csk.Q38058787
In vitro models for glaucoma research: effects of hydrostatic pressure.Q39520588
Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism.Q40496060
Role of vav1- and src-related tyrosine kinases in macrophage activation by CpG DNA.Q40594724
Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.Q41075059
Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashionQ41311919
Activation of Src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemiaQ42477402
Monokine production by microglial cell clonesQ42816910
c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expressionQ44367846
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells.Q44405169
Differential turnover rates of monocyte-derived cells in varied ocular tissue microenvironments.Q50630421
Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner.Q53278044
Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1.Q54342618
Comparison of polarization properties of human adult microglia and blood-derived macrophagesQ57041309
P433issue3
P921main subjectmicrogliaQ1622829
P304page(s)497-511
P577publication date2014-11-24
P1433published inGliaQ15716658
P1476titlec-Src function is necessary and sufficient for triggering microglial cell activation
P478volume63

Reverse relations

cites work (P2860)
Q48310351Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK-STAT Pathway.
Q41957673Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation.
Q52682216Effect of Qingguang'an II on expressions of OX42 protein and IL-1β mRNA of retinal microglia cells of rats with chronic high intraocular pressure.
Q47727115Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke.
Q61757974Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury
Q90054655Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson's Disease Models
Q36334069The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain

Search more.