| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/IJC.29350 |
| P698 | PubMed publication ID | 25408501 |
| P50 | author | Joanna L Fox | Q62088208 |
| Alan Storey | Q64101624 | ||
| P2093 | author name string | Mark Simmonds | |
| Abul Azad | |||
| Amy Holloway | |||
| P2860 | cites work | To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. | Q46142204 |
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| Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis | Q53294841 | ||
| Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria | Q22011013 | ||
| Bcl-2 family interaction with the mitochondrial morphogenesis machinery | Q24293601 | ||
| BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove | Q24295530 | ||
| Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis | Q24306444 | ||
| Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis | Q24670370 | ||
| Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis | Q27734734 | ||
| BH3-ligand regulates access of MCL-1 to its E3 ligase | Q28276218 | ||
| The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
| The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis. | Q33292139 | ||
| Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types | Q33292386 | ||
| The role of the E6-p53 interaction in the molecular pathogenesis of HPV. | Q33807833 | ||
| A new quantitative assay for cytochrome c release in apoptotic cells. | Q34207175 | ||
| Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis | Q34493785 | ||
| Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2 | Q35010932 | ||
| Accelerated degradation of FADD and procaspase 8 in cells expressing human papilloma virus 16 E6 impairs TRAIL-mediated apoptosis | Q35082804 | ||
| The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis | Q35131647 | ||
| Detection of human papillomavirus DNA in cutaneous squamous cell carcinoma among immunocompetent individuals | Q35711739 | ||
| HPV-associated skin disease. | Q36346158 | ||
| Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. | Q36660357 | ||
| Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain | Q36777990 | ||
| Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | Q37068553 | ||
| Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members | Q37237621 | ||
| Tyrosine dephosphorylation is required for Bak activation in apoptosis | Q39642126 | ||
| Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis | Q39946627 | ||
| E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation | Q39948840 | ||
| The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes | Q40015766 | ||
| Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria | Q40188786 | ||
| TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase. | Q40319463 | ||
| Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins | Q40445624 | ||
| Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals. | Q40760209 | ||
| E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage | Q40896659 | ||
| Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins | Q40993031 | ||
| Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus | Q41811806 | ||
| Increased risk of skin cancer associated with the presence of epidermodysplasia verruciformis human papillomavirus types in normal skin | Q42461793 | ||
| Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD. | Q42707106 | ||
| Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices | Q43235008 | ||
| Beta-papillomavirus DNA loads in hair follicles of immunocompetent people and organ transplant recipients | Q43428036 | ||
| Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak. | Q43830983 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | proteolysis | Q33123 |
| P1104 | number of pages | 13 | |
| P304 | page(s) | 2831-2843 | |
| P577 | publication date | 2014-12-15 | |
| P1433 | published in | International Journal of Cancer | Q332492 |
| P1476 | title | Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase | |
| P478 | volume | 136 |
| Q91650119 | Beta HPV Type 15 Can Interfere With NF-κB Activity and Apoptosis in Human Keratinocytes |
| Q38711737 | Complex formation and turnover of mitochondrial transporters and ion channels |
| Q37619334 | Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation. |
| Q55054189 | Cutaneous Papillomaviruses and Non-melanoma Skin Cancer: Causal Agents or Innocent Bystanders? |
| Q50316561 | Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis |
| Q36720528 | E6 proteins from low-risk human papillomavirus types 6 and 11 are able to protect keratinocytes from apoptosis via Bak degradation |
| Q28078631 | Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites |
| Q34510463 | Functional and pathological relevance of HERC family proteins: a decade later. |
| Q92856896 | HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases |
| Q89834860 | HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy? |
| Q45393476 | Loss of Genome Fidelity: Beta HPVs and the DNA Damage Response |
| Q39434895 | Molecular Mechanisms of Human Papillomavirus Induced Skin Carcinogenesis |
| Q40327423 | Mucosal alpha-papillomaviruses are not associated with esophageal squamous cell carcinomas: Lack of mechanistic evidence from South Africa, China and Iran and from a world-wide meta-analysis |
| Q64256422 | Mucosal and Cutaneous Human Papillomavirus Infections and Cancer Biology |
| Q63359720 | Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy |
| Q28081948 | The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle |
| Q39011155 | The biology of beta human papillomaviruses |
| Q47098228 | The interplay of UV and cutaneous papillomavirus infection in skin cancer development |
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