High glucose inhibits receptor activator of nuclear factor‑κB ligand-induced osteoclast differentiation via downregulation of v‑ATPase V0 subunit d2 and dendritic cell‑specific transmembrane protein

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High glucose inhibits receptor activator of nuclear factor‑κB ligand-induced osteoclast differentiation via downregulation of v‑ATPase V0 subunit d2 and dendritic cell‑specific transmembrane protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/MMR.2014.2807
P932PMC publication ID4262508
P698PubMed publication ID25352342
P5875ResearchGate publication ID267745090

P2093author name stringLi Chen
Wenbo Qi
Juan Xu
Feng Yue
Jingbo Wang
P2860cites workNF-κB p50 and p52 Regulate Receptor Activator of NF-κB Ligand (RANKL) and Tumor Necrosis Factor-induced Osteoclast Precursor Differentiation by Activating c-Fos and NFATc1Q57675122
Fosl1 is a transcriptional target of c-Fos during osteoclast differentiationQ57675158
Genetic control of skeletal developmentQ58326890
c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodelingQ58326943
Bone and haematopoietic defects in mice lacking c-fosQ58326969
Tetracycline administration normalizes the structure and acid phosphatase activity of osteoclasts in streptozotocin-induced diabetic ratsQ68475031
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formationQ79383955
Hyperglycemia Impairs Skeletogenesis from Embryonic Stem Cells by Affecting Osteoblast and Osteoclast DifferentiationQ85183080
RANK is essential for osteoclast and lymph node developmentQ24598872
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand familiesQ28137631
Bone resorption by osteoclastsQ28145169
Disorders of Bone RemodelingQ28295303
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cellsQ28506839
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cellsQ28589731
Osteoclast differentiation and activationQ29547556
Genetic regulation of osteoclast development and functionQ29617421
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclastsQ29618116
Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studiesQ36028626
Fos/AP-1 proteins in bone and the immune systemQ36324940
Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysisQ36636165
The molecular understanding of osteoclast differentiationQ36650749
Are nonresorbing osteoclasts sources of bone anabolic activity?Q36709511
Systematic review of type 1 and type 2 diabetes mellitus and risk of fractureQ36851830
Diabetes and fractures: an overshadowed associationQ37102803
NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).Q37302319
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-FosQ38342636
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulatorQ38363724
High d(+)glucose concentration inhibits RANKL-induced osteoclastogenesisQ39996770
Prevalence and control of diabetes in Chinese adultsQ40134909
Purification of RNA using TRIzol (TRI reagent).Q43048322
Curcumin suppresses increased bone resorption by inhibiting osteoclastogenesis in rats with streptozotocin-induced diabetesQ43287788
Sclerostin levels associated with inhibition of the Wnt/β-catenin signaling and reduced bone turnover in type 2 diabetes mellitusQ43739331
The effects of systemic insulin, insulin-like growth factor-I and growth hormone on bone growth and turnover in spontaneously diabetic BB ratsQ43918360
Serum levels of bone resorption markers are decreased in patients with type 2 diabetesQ44094049
Tissue mineralization is increased following 1-year treatment with high doses of bisphosphonates in dogsQ44695650
Inhibitory effects of high glucose/insulin environment on osteoclast formation and resorption in vitroQ45021787
Thioredoxin-1 overexpression in transgenic mice attenuates streptozotocin-induced diabetic osteopenia: a novel role of oxidative stress and therapeutic implications.Q46161156
Osteoclastic function is accelerated in male patients with type 2 diabetes mellitus: the preventive role of osteoclastogenesis inhibitory factor/osteoprotegerin (OCIF/OPG) on the decrease of bone mineral densityQ46462609
Microdamage accumulation in the monkey vertebra does not occur when bone turnover is suppressed by 50% or less with estrogen or raloxifeneQ46571677
Bone formation in spontaneously diabetic Torii-newly established model of non-obese type 2 diabetes rats.Q46883073
The effects of local platelet rich plasma delivery on diabetic fracture healing.Q51301204
Histomorphometric analysis of diabetic osteopenia in streptozotocin-induced diabetic mice: a possible role of oxidative stress.Q53575266
Induction of DC-STAMP by Alternative Activation and Downstream Signaling MechanismsQ57675118
P433issue2
P921main subjecttransmembrane proteinQ424204
dendritic cellQ506253
P304page(s)865-870
P577publication date2014-10-29
P1433published inMolecular Medicine ReportsQ26842180
P1476titleHigh glucose inhibits receptor activator of nuclear factor‑κB ligand-induced osteoclast differentiation via downregulation of v‑ATPase V0 subunit d2 and dendritic cell‑specific transmembrane protein
P478volume11

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cites work (P2860)
Q38939772A new perspective on mechanisms governing skeletal complications in type 1 diabetes
Q42504968High glucose alters the secretome of mechanically stimulated osteocyte-like cells affecting osteoclast precursor recruitment and differentiation.
Q35234933MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
Q38888332N-acetylglucosamine suppresses osteoclastogenesis in part through the promotion of O-GlcNAcylation.
Q90218092Osteoclasts in bone regeneration under type 2 diabetes mellitus
Q39127683Pathophysiology of Bone Fragility in Patients with Diabetes.
Q58725004Skeletal Fragility in Type 2 Diabetes Mellitus
Q33766770Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis.
Q58795849Type 2 diabetes affects bone cells precursors and bone turnover
Q64230394Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties

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