review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00249-016-1169-3 |
P8608 | Fatcat ID | release_k2rauqzfejbkljfhrf2yiijfle |
P698 | PubMed publication ID | 27649700 |
P2093 | author name string | Saverio Gentile | |
P2860 | cites work | Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development | Q24646866 |
hERG channel function: beyond long QT | Q27008078 | ||
Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2 | Q28145423 | ||
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS | Q28202269 | ||
Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes | Q28291447 | ||
Mutational landscape and significance across 12 major cancer types | Q28300353 | ||
A structural basis for drug-induced long QT syndrome | Q28344808 | ||
HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells | Q28539628 | ||
Regulation of an ERG K+ current by Src tyrosine kinase | Q28581012 | ||
Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality. | Q30491532 | ||
Sudden arrhythmia death syndrome: importance of the long QT syndrome. | Q33149251 | ||
Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for I(Ks). | Q33661049 | ||
Four faces of cellular senescence. | Q34025754 | ||
Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1. | Q34152898 | ||
Expression and role of hERG channels in cancer cells. | Q34437815 | ||
hERG potassium channels and cardiac arrhythmia | Q34504394 | ||
Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients | Q34621219 | ||
Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells | Q35176400 | ||
ERG conductance expression modulates the excitability of ventral horn GABAergic interneurons that control rhythmic oscillations in the developing mouse spinal cord | Q79655193 | ||
[Novel methylation and expression markers associated with breast cancer] | Q81441557 | ||
Is erythromycin therapy teratogenic in humans? | Q81770658 | ||
Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits | Q82768867 | ||
E- and A-type cyclins as markers for cancer diagnosis and prognosis | Q35543902 | ||
Choosing the right cell line for breast cancer research | Q35608671 | ||
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs | Q36849934 | ||
Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program | Q36973723 | ||
Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel | Q36975149 | ||
Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma | Q37225455 | ||
Targeting ion channels in cancer: a novel frontier in antineoplastic therapy | Q37370358 | ||
Assessing proarrhythmic potential of drugs when optimal studies are infeasible. | Q37450211 | ||
Voltage-gated potassium channels as therapeutic targets | Q37464784 | ||
hERG1/Kv11.1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism | Q37644785 | ||
Role of autophagy in cancer prevention | Q37898320 | ||
hERG K(+) channels: structure, function, and clinical significance | Q38044402 | ||
Role of autophagy in cancer prevention, development and therapy | Q38144288 | ||
Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells | Q38361021 | ||
Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells | Q39444757 | ||
Human ether-à-go-go-related gene expression is essential for cisplatin to induce apoptosis in human gastric cancer | Q39454149 | ||
Electrophysiological effects of the anti-cancer drug lapatinib on cardiac repolarization | Q39712812 | ||
Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration | Q39797663 | ||
Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo | Q40058589 | ||
Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets | Q42060620 | ||
Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression | Q42715022 | ||
Regulation of the voltage-insensitive step of HERG activation by extracellular pH. | Q43110152 | ||
Erg K+ currents modulate excitability in mouse mitral/tufted neurons | Q43290379 | ||
Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate | Q43514924 | ||
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? | Q44004456 | ||
ERG K+ channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death? | Q44254910 | ||
Expression and function of KCNH2 (HERG) in the human jejunum | Q44433185 | ||
Effect of Arsenic Trioxide on QT Interval in Patients With Advanced Malignancies | Q44598288 | ||
Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons | Q46054857 | ||
The potent inhibitory effects of cisapride, a specific blocker for human ether-a-go-go-related gene (HERG) channel, on gastric cancer cells | Q46450387 | ||
Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome | Q46681639 | ||
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs | Q46807818 | ||
HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives | Q48501900 | ||
herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells? | Q48945547 | ||
erg gene(s) expression during development of the nervous and muscular system of quail embryos. | Q52166642 | ||
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment. | Q52590496 | ||
Arsenic trioxide inhibits breast cancer cell growth via microRNA-328/hERG pathway in MCF-7 cells. | Q53564372 | ||
HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. | Q53866705 | ||
Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia. | Q54334505 | ||
Expression and Role of hERG Channels in Cancer Cells | Q56420805 | ||
Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRP1 ion channel: implications for acquired and congenital long Q-T syndrome | Q57807317 | ||
Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release | Q73251237 | ||
P433 | issue | 7 | |
P304 | page(s) | 649-655 | |
P577 | publication date | 2016-09-20 | |
P1433 | published in | European Biophysics Journal | Q5412316 |
P1476 | title | hERG1 potassium channel in cancer cells: a tool to reprogram immortality | |
P478 | volume | 45 |