scholarly article | Q13442814 |
P2093 | author name string | Emerson BM | |
Espinosa JM | |||
P2860 | cites work | Promoter structure and transcriptional activation with chromatin templates assembled in vitro. A single Gal4-VP16 dimer binds to chromatin or to DNA with comparable affinity | Q46113275 |
DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53 | Q73615085 | ||
Scanning force microscopy of the complexes of p53 core domain with supercoiled DNA | Q73843198 | ||
Signaling to p53: breaking the MDM2-p53 circuit | Q77430977 | ||
A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro | Q22003978 | ||
Functional selectivity of recombinant mammalian SWI/SNF subunits | Q24290358 | ||
High mobility group protein-1 (HMG-1) is a unique activator of p53 | Q24311393 | ||
Binding and modulation of p53 by p300/CBP coactivators | Q24312018 | ||
p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage | Q24530584 | ||
ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly | Q24602406 | ||
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain | Q27860534 | ||
p53, the cellular gatekeeper for growth and division | Q27860990 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3 | Q27931527 | ||
Surfing the p53 network | Q28032484 | ||
Deacetylation of p53 modulates its effect on cell growth and apoptosis | Q28138967 | ||
Atmospheric carbon dioxide concentrations over the past 60 million years | Q28144787 | ||
Recruitment of p300/CBP in p53-dependent signal pathways | Q28243213 | ||
p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
Activation and repression mechanisms in yeast | Q33671494 | ||
Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. | Q33921258 | ||
Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates | Q33960598 | ||
Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53 | Q35205701 | ||
p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting | Q37161582 | ||
Ligand-dependent activation of transcription in vitro by retinoic acid receptor alpha/retinoid X receptor alpha heterodimers that mimics transactivation by retinoids in vivo | Q37167696 | ||
Regulation of the specific DNA binding function of p53 | Q38324290 | ||
Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination | Q39540284 | ||
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification | Q40843110 | ||
Influence of promoter DNA topology on sequence-specific DNA binding and transactivation by tumor suppressor p53. | Q40911280 | ||
Constitutive expression of the cyclin-dependent kinase inhibitor p21 is transcriptionally regulated by the tumor suppressor protein p53. | Q41000380 | ||
The N terminus of p53 regulates its dissociation from DNA. | Q42055738 | ||
P433 | issue | 1 | |
P304 | page(s) | 57-69 | |
P577 | publication date | 2001-07-01 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment | |
P478 | volume | 8 |
Q38349842 | A Defect in the p53 Response Pathway Induced by de Novo Purine Synthesis Inhibition |
Q88657769 | A Designed Enzyme Promotes Selective Post-translational Acylation |
Q90192681 | A Protein in the Yeast Saccharomyces cerevisiae Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor |
Q37249372 | A complex barcode underlies the heterogeneous response of p53 to stress |
Q38876081 | A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097. |
Q24300728 | A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis |
Q40711394 | A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions |
Q36025444 | A novel roll-and-slide mechanism of DNA folding in chromatin: implications for nucleosome positioning |
Q34210459 | A p53-dependent promoter associated with polymorphic tandem repeats controls the expression of a viral transcript encoding clustered microRNAs |
Q35856748 | A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. |
Q24656968 | A transcription cofactor required for the heat-shock response |
Q36315950 | A unique DNA binding domain converts T-cell factors into strong Wnt effectors |
Q24313477 | Acetylation is indispensable for p53 activation |
Q77456357 | Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases |
Q34520098 | Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). |
Q36601373 | Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo |
Q40687477 | Acetylation regulates the DNA end-trimming activity of DNA polymerase beta |
Q34605518 | Activation of the p53 tumor suppressor protein |
Q36732343 | Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity |
Q24300158 | An acetylation switch in p53 mediates holo-TFIID recruitment |
Q40175886 | An essential role of human Ada3 in p53 acetylation |
Q38307906 | An integrated map of p53-binding sites and histone modification in the human ENCODE regions |
Q38353498 | Analysis of p53 "latency" and "activation" by fluorescence correlation spectroscopy. Evidence for different modes of high affinity DNA binding. |
Q78679366 | Atomic force microscopy reveals kinks in the p53 response element DNA |
Q39430447 | Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53 |
Q24317756 | BAF60a interacts with p53 to recruit the SWI/SNF complex |
Q73905084 | BRCA1: a scaffold for p53 response? |
Q34013630 | Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association |
Q40570060 | Binding of RNA to p53 regulates its oligomerization and DNA-binding activity |
Q40014129 | C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity |
Q28235350 | CDK8 is a stimulus-specific positive coregulator of p53 target genes |
Q36370912 | CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene |
Q24800091 | CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activity |
Q38351593 | Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses |
Q39321805 | Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1. |
Q36777343 | Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson |
Q40218004 | Characterization of genomic changes in the cervical pre-cancerous lesions and tumors induced by different types of human papillomaviruses |
Q33896638 | Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo |
Q28590990 | Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression |
Q33593991 | Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. |
Q38359899 | Constitutive DNase I hypersensitivity of p53-regulated promoters |
Q28236097 | Control of the G2/M transition |
Q39733989 | Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression |
Q38984847 | Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters |
Q46985048 | Crosstalk between site-specific modifications on p53 and histone H3. |
Q24311663 | Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding |
Q60357497 | DNA binding and 3′–5′ exonuclease activity in the murine alternatively-spliced p53 protein |
Q37181510 | DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling |
Q53598752 | DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner |
Q39424192 | DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death. |
Q42435054 | DNA-dependent acetylation of p53 by the transcription coactivator p300. |
Q45054555 | Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation |
Q58580342 | Defining TP53 pioneering capabilities with competitive nucleosome binding assays |
Q34443272 | Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence. |
Q42724753 | Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters. |
Q39848157 | Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein |
Q35101871 | Drug discovery and p53. |
Q30819886 | Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands |
Q37731957 | E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. |
Q51186530 | Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains |
Q39675422 | Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein |
Q34490497 | Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA |
Q33278013 | Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. |
Q53335869 | Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention. |
Q39647839 | Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells |
Q40290190 | Excess HDM2 impacts cell cycle and apoptosis and has a selective effect on p53-dependent transcription. |
Q42476896 | Exploring a minimal two-component p53 model |
Q34865226 | Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements |
Q33863075 | Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity |
Q33772124 | Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. |
Q28584780 | GCN5 and p300 share essential functions during early embryogenesis |
Q33839575 | Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding. |
Q35906476 | Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-kappaB and other signal transcription factors in head and neck squamous cell carcinoma. |
Q33659512 | Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. |
Q40421589 | HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage |
Q37402028 | HIPK2 modulates p53 activity towards pro-apoptotic transcription |
Q24301527 | HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53 |
Q38572921 | Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors |
Q33802917 | How does SIRT1 affect metabolism, senescence and cancer? |
Q36879036 | How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? |
Q39997408 | How p53 wields the scales of fate: arrest or death? |
Q39565523 | Human EHMT2/G9a activates p53 through methylation-independent mechanism |
Q24294875 | Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response |
Q24297146 | Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence |
Q36738940 | Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. |
Q45729740 | Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcription |
Q35640132 | Identification of Kinase Inhibitors that Target Transcription Initiation by RNA Polymerase II |
Q34366021 | Identification of PRC1 as the p53 target gene uncovers a novel function of p53 in the regulation of cytokinesis |
Q31134749 | Identification of small-molecule antagonists that inhibit an activator: coactivator interaction |
Q34547679 | Impact of Alu repeats on the evolution of human p53 binding sites |
Q37021730 | Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. |
Q40639210 | Induction of p53-dependent activation of the human proliferating cell nuclear antigen gene in chromatin by ionizing radiation. |
Q36906240 | Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics |
Q64072077 | Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy |
Q24310030 | Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53 |
Q35183861 | Intrasteric regulation of MDM2. |
Q24527652 | Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element |
Q40570035 | Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. |
Q29547663 | Live or let die: the cell's response to p53 |
Q42490237 | Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency |
Q38168223 | Lysine-specific modifications of p53: a matter of life and death? |
Q78826588 | Macrophage migration inhibitory factor deficiency is associated with altered cell growth and reduced susceptibility to Ras-mediated transformation |
Q35572466 | Mdm2: A regulator of cell growth and death |
Q26741834 | Mechanisms of Hsp90 regulation |
Q34688357 | Mechanisms of chromatin assembly and transcription |
Q34039841 | Mechanisms of regulatory diversity within the p53 transcriptional network |
Q47416965 | Mechanisms of transcriptional regulation by p53. |
Q30374671 | Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer. |
Q29615657 | Modes of p53 regulation |
Q33399356 | Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences |
Q36436702 | Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo |
Q34080682 | Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation |
Q91626701 | Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation |
Q24791476 | Mutant p53 proteins bind DNA in a DNA structure-selective mode |
Q34416303 | Myelin-derived lipids modulate macrophage activity by liver X receptor activation |
Q24297694 | NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. |
Q74631439 | NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNA |
Q38657267 | New Phage Display-Isolated Heptapeptide Recognizing the Regulatory Carboxy-Terminal Domain of Human Tumour Protein p53. |
Q33361623 | Noncanonical DNA motifs as transactivation targets by wild type and mutant p53 |
Q51836900 | Nuclear delivery of p53 C-terminal peptides into cancer cells using scFv fragments of a monoclonal antibody that penetrates living cells |
Q39159757 | Nuclear phosphoinositide regulation of chromatin. |
Q35785876 | Of flies and men; p53, a tumour suppressor |
Q28265932 | Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53 |
Q24317150 | P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain |
Q34828404 | P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements. |
Q40616826 | PCAF is a coactivator for p73-mediated transactivation |
Q35149631 | Phosphorylation of Tip60 by p38α regulates p53-mediated PUMA induction and apoptosis in response to DNA damage |
Q34697693 | Pioneer transcription factors in cell reprogramming |
Q35930703 | Post-translational modification of p53 in tumorigenesis |
Q33899450 | Posttranslational modification of p53: cooperative integrators of function |
Q34651573 | Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells. |
Q37154221 | Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts |
Q38855681 | Quaternary structure of the specific p53-DNA complex reveals the mechanism of p53 mutant dominance |
Q36777373 | Reactivation of mutant p53: molecular mechanisms and therapeutic potential |
Q39615561 | Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277 |
Q34094598 | Regulation and functional contribution of thymidine kinase 1 in repair of DNA damage |
Q35998100 | Regulation of STAT signaling by acetylation |
Q24677861 | Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins |
Q39474865 | Regulation of histone acetylation by NDRG2 in glioma cells |
Q35116637 | Regulation of p53 responses by post-translational modifications |
Q39978322 | Regulation of p53 target gene expression by peptidylarginine deiminase 4 |
Q37636014 | Regulation of p53--insights into a complex process |
Q25256835 | Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. |
Q45000475 | Repression of hsp90beta gene by p53 in UV irradiation-induced apoptosis of Jurkat cells |
Q38333341 | Restoration of tumor suppressor p53 by differentially regulating pro- and anti-p53 networks in HPV-18-infected cervical cancer cells. |
Q24613365 | Reverse Transcriptase-Coupled Quantitative Real Time PCR Analysis of Cell-Free Transcription on the Chromatin-Assembled p21 Promoter |
Q35089524 | Review of Chromium (VI) Apoptosis, Cell-Cycle-Arrest, and Carcinogenesis |
Q37518662 | Rotational positioning of nucleosomes facilitates selective binding of p53 to response elements associated with cell cycle arrest |
Q34330055 | Sequence-dependent Kink-and-Slide deformations of nucleosomal DNA facilitated by histone arginines bound in the minor groove |
Q33988397 | Skp2B Overexpression Alters a Prohibitin-p53 Axis and the Transcription of PAPP-A, the Protease of Insulin-Like Growth Factor Binding Protein 4 |
Q37092878 | Slicing across kingdoms: regeneration in plants and animals |
Q36430175 | Sliding into home: facilitated p53 search for targets by the basic DNA binding domain |
Q83455104 | Sliding of p53 along DNA Can Be Modulated by Its Oligomeric State and by Cross-Talks between Its Constituent Domains |
Q37172739 | Smad3 activates the Sox9-dependent transcription on chromatin |
Q40383677 | Sox9 and p300 cooperatively regulate chromatin-mediated transcription |
Q38363728 | Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain |
Q24653926 | Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation |
Q35967111 | Surf the post-translational modification network of p53 regulation |
Q37536938 | Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer. |
Q24317246 | Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53 |
Q38059739 | Targeting the Ubiquitin-Mediated Proteasome Degradation of p53 for Cancer Therapy |
Q37117705 | Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex |
Q24556628 | The C terminus of p53 family proteins is a cell fate determinant |
Q28507164 | The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo |
Q47319323 | The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1. |
Q91643306 | The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors |
Q40163084 | The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members |
Q31023819 | The Proline Repeat Domain of p53 Binds Directly to the Transcriptional Coactivator p300 and Allosterically Controls DNA-Dependent Acetylation of p53 |
Q39927575 | The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis |
Q38964688 | The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein. |
Q40682154 | The acetylase activity of p300 is dispensable for MDM2 stabilization |
Q34770071 | The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells |
Q40667519 | The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein. |
Q24297814 | The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes |
Q34519833 | The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes |
Q35191541 | The complex interactions of p53 with target DNA: we learn as we go. |
Q36443523 | The complexity of p53 stabilization and activation |
Q36259624 | The contribution of transactivation subdomains 1 and 2 to p53-induced gene expression is heterogeneous but not subdomain-specific |
Q90113081 | The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network |
Q34487385 | The evolution of diverse biological responses to DNA damage: insights from yeast and p53 |
Q37602507 | The expanding universe of p53 targets |
Q39673506 | The expression ofp53-regulated genes in human cultured lymphoblastoid TSCE5 and WTK1 cell lines during spaceflight |
Q36542788 | The impact of post-transcriptional regulation in the p53 network |
Q89289431 | The mechanistic basis for chromatin regulation by pioneer transcription factors |
Q92062954 | The multiple mechanisms that regulate p53 activity and cell fate |
Q58430752 | The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain |
Q33724426 | The p53 tumor suppressor protein represses human snRNA gene transcription by RNA polymerases II and III independently of sequence-specific DNA binding |
Q28588064 | The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting |
Q41225724 | The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion |
Q44418946 | The role of p53 deacetylation in p21Waf1 regulation by laminar flow |
Q38977312 | The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity |
Q34888585 | The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. |
Q36423929 | The versatile interactions of p53 with DNA: when flexibility serves specificity |
Q35095843 | Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis. |
Q34100529 | Tracing the protectors path from the germ line to the genome |
Q33598618 | Transcription coactivator CBP has direct DNA binding activity and stimulates transcription factor DNA binding through small domains |
Q39005896 | Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53. |
Q29617650 | Transcriptional control of human p53-regulated genes |
Q37777267 | Transcriptional regulation by p53. |
Q36436698 | Transcriptional regulation by p53: one protein, many possibilities |
Q34814407 | Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells |
Q24537716 | Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes |
Q39991040 | Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis |
Q36717623 | Tumor suppressor p53 slides on DNA with low friction and high stability |
Q33707419 | USP7/HAUSP Promotes the Sequence-Specific DNA Binding Activity of p53 |
Q35089377 | Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation |
Q36318145 | Viruses - seeking and destroying the tumor program |
Q24594980 | Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail |
Q53252468 | Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers |
Q34486036 | Why Is p53 Acetylated? |
Q39822156 | Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation |
Q40142210 | hAda3 regulates p14ARF-induced p53 acetylation and senescence |
Q38959783 | hERG1 potassium channel in cancer cells: a tool to reprogram immortality |
Q33905382 | p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels |
Q35779695 | p300/CBP and cancer |
Q58918367 | p53 |
Q28609701 | p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage |
Q36401999 | p53 N-terminal phosphorylation: a defining layer of complex regulation |
Q28215076 | p53 Transcriptional Activity Is Mediated through the SRC1-interacting Domain of CBP/p300 |
Q35646680 | p53 and p73 display common and distinct requirements for sequence specific binding to DNA |
Q36052576 | p53 basic C terminus regulates p53 functions through DNA binding modulation of subset of target genes |
Q47140890 | p53 binding sites in normal and cancer cells are characterized by distinct chromatin context. |
Q33569713 | p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element |
Q38341581 | p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy |
Q27305159 | p53 dynamics upon response element recognition explored by molecular simulations |
Q33376888 | p53 induces distinct epigenetic states at its direct target promoters |
Q39714641 | p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage |
Q43293646 | p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity |
Q57929625 | p53 latency – out of the blind alley |
Q40344795 | p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene |
Q40715545 | p53 requires an intact C-terminal domain for DNA binding and transactivation |
Q36567469 | p53 sumoylation: mechanistic insights from reconstitution studies |
Q42660335 | p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression |
Q42098836 | p53-Dependent p21 mRNA elongation is impaired when DNA replication is stalled. |
Q44945710 | p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress |
Q34517061 | p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network. |
Q58543844 | p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion |
Q38319824 | tumor suppressor p53 binds with high affinity to CTG.CAG trinucleotide repeats and induces topological alterations in mismatched duplexes |
Q36654367 | ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells. |
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