| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/PATH.4813 |
| P698 | PubMed publication ID | 27701736 |
| P50 | author | Cheng-Hsuan Chiang | Q56335411 |
| P2093 | author name string | David W Ellison | |
| P2860 | cites work | Cancer-associated IDH1 mutations produce 2-hydroxyglutarate | Q24320239 |
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| Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases | Q24632807 | ||
| Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Q24651548 | ||
| Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations | Q24684853 | ||
| One hundred and one dysembryoplastic neuroepithelial tumors: an adult epilepsy series with immunohistochemical, molecular genetic, and clinical correlations and a review of the literature | Q26863688 | ||
| Criteria for inference of chromothripsis in cancer genomes | Q27000794 | ||
| Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition | Q27852966 | ||
| Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma | Q28237518 | ||
| Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations | Q28237528 | ||
| Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma | Q28237604 | ||
| Subgroup-specific structural variation across 1,000 medulloblastoma genomes | Q28271811 | ||
| Central nervous system atypical teratoid/rhabdoid tumor: results of therapy in children enrolled in a registry | Q28272148 | ||
| Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer | Q28277002 | ||
| TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma | Q37316068 | ||
| The changing epidemiology of paediatric brain tumours: a review from the Hospital for Sick Children | Q37350651 | ||
| Posterior fossa and spinal gangliogliomas form two distinct clinicopathologic and molecular subgroups. | Q37597227 | ||
| Histology and molecular pathology of pediatric brain tumors | Q37617838 | ||
| Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma | Q37705192 | ||
| Incidence of atypical teratoid/rhabdoid tumors in children: a population-based study by the Austrian Brain Tumor Registry, 1996-2006. | Q37782304 | ||
| Diffuse form of dysembryoplastic neuroepithelial tumour: the histological and immunohistochemical features of a distinct entity showing transition to dysembryoplastic neuroepithelial tumour and ganglioglioma. | Q37944284 | ||
| Central nervous system atypical teratoid rhabdoid tumours: the Canadian Paediatric Brain Tumour Consortium experience. | Q37949049 | ||
| Occurrence and distribution of pilomyxoid astrocytoma | Q38071109 | ||
| Advances in the management of central nervous system germ cell tumors | Q38212603 | ||
| Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma | Q38259785 | ||
| Medulloblastoma-translating discoveries from the bench to the bedside | Q38263111 | ||
| Pilocytic astrocytoma: pathology, molecular mechanisms and markers. | Q38384754 | ||
| Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma | Q34810691 | ||
| Pleomorphic Xanthoastrocytoma: Natural History and Long-Term Follow-Up | Q35449751 | ||
| Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma | Q35532490 | ||
| Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes | Q35692614 | ||
| Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA. | Q35752324 | ||
| Chromosomal imbalances in choroid plexus tumors | Q35788860 | ||
| Malignant and benign ganglioglioma: a pathological and molecular study | Q35800003 | ||
| A case of solitary subependymal giant cell astrocytoma: two somatic hits of TSC2 in the tumor, without evidence of somatic mosaicism | Q35836708 | ||
| Novel somatic and germline mutations in intracranial germ cell tumours. | Q35940152 | ||
| The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma | Q35993240 | ||
| Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy | Q36001219 | ||
| A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers | Q36129157 | ||
| Novel mutations target distinct subgroups of medulloblastoma. | Q36143877 | ||
| Epithelioid GBMs show a high percentage of BRAF V600E mutation. | Q36175648 | ||
| Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups | Q36460209 | ||
| Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups | Q36461766 | ||
| Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner. | Q36464991 | ||
| Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables | Q36476670 | ||
| BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas | Q36532504 | ||
| The pilomyxoid astrocytoma and its relationship to pilocytic astrocytoma: report of a case and a critical review of the entity | Q36540545 | ||
| Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations | Q36612342 | ||
| Gangliogliomas: a clinicopathological study of 25 cases and review of the literature | Q36746001 | ||
| TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal | Q36762656 | ||
| Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations. | Q36771546 | ||
| Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas | Q36780903 | ||
| The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression | Q36850449 | ||
| Classification and grading of low-grade astrocytic tumors in children | Q36862370 | ||
| Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. | Q36900873 | ||
| Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma | Q36929844 | ||
| Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas | Q36981245 | ||
| Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas | Q37055286 | ||
| Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas | Q37238690 | ||
| Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors | Q37289800 | ||
| Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome | Q28298987 | ||
| Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas | Q28305680 | ||
| JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice | Q28587091 | ||
| Super-enhancers in the control of cell identity and disease | Q28661442 | ||
| Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Q29616862 | ||
| Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms | Q29618586 | ||
| Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations | Q30040534 | ||
| CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. | Q30402063 | ||
| Nevoid basal cell carcinoma syndrome: relation with desmoplastic medulloblastoma in infancy. A population-based study and review of the literature | Q30968980 | ||
| A prognostic gene expression signature in infratentorial ependymoma | Q33581494 | ||
| Clinical, radiological, histological and molecular characteristics of paediatric epithelioid glioblastoma | Q33702910 | ||
| C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma | Q33730977 | ||
| The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma | Q33751426 | ||
| Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene | Q33772206 | ||
| Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas | Q33813999 | ||
| BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications | Q33867475 | ||
| Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity | Q33917715 | ||
| Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease | Q33990951 | ||
| Cross-species genomics matches driver mutations and cell compartments to model ependymoma | Q34031780 | ||
| Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma | Q34132926 | ||
| Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas | Q34132964 | ||
| CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity | Q34157312 | ||
| Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas | Q34167499 | ||
| Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas | Q34184430 | ||
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy | Q34240198 | ||
| Choroid plexus papilloma in a girl with hypomelanosis of Ito. | Q34336841 | ||
| Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1 | Q34342166 | ||
| Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma | Q34354839 | ||
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma | Q34362028 | ||
| Radial glia cells are candidate stem cells of ependymoma | Q34459796 | ||
| New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs | Q34515911 | ||
| Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome | Q34646450 | ||
| Dysembryoplastic neuroepithelial tumor: a surgically curable tumor of young patients with intractable partial seizures. Report of thirty-nine cases | Q34685937 | ||
| Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group | Q34722864 | ||
| The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary | Q38829244 | ||
| Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. | Q39173934 | ||
| Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma | Q39788891 | ||
| Landscape of chromosomal copy number aberrations in gangliogliomas and dysembryoplastic neuroepithelial tumours | Q41238200 | ||
| Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers | Q41264935 | ||
| High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN). | Q41494035 | ||
| Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors | Q41817349 | ||
| Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma | Q41888346 | ||
| Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma | Q42636358 | ||
| Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma | Q42812964 | ||
| Epidemiology of central nervous system tumors in childhood and adolescence based on the new WHO classification | Q43569987 | ||
| Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression | Q43838170 | ||
| Frequency, risk-factors and survival of children with atypical teratoid rhabdoid tumors (AT/RT) of the CNS diagnosed between 1988 and 2004, and registered to the German HIT database | Q43944813 | ||
| Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma | Q44739121 | ||
| Genome-wide DNA copy number analysis of desmoplastic infantile astrocytomas and desmoplastic infantile gangliogliomas | Q44890960 | ||
| Incidence patterns for ependymoma: a surveillance, epidemiology, and end results study. | Q45944762 | ||
| Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups | Q46158282 | ||
| Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas--Same Entity or First Cousins? | Q46365183 | ||
| Immunohistochemical analysis of hSNF5/INI1 in pediatric CNS neoplasms | Q47708980 | ||
| Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. | Q47992753 | ||
| Ganglioglioma: a detailed histopathological and immunohistochemical analysis of 61 cases | Q48218230 | ||
| Histological heterogeneity of dysembryoplastic neuroepithelial tumour: identification and differential diagnosis in a series of 74 cases | Q48219312 | ||
| Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior | Q48227672 | ||
| Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes. | Q48229405 | ||
| Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution | Q48231129 | ||
| Clinical and molecular characteristics of malignant transformation of low-grade glioma in children | Q48269415 | ||
| Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets | Q48315065 | ||
| Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma | Q48329991 | ||
| Disseminated oligodendroglial-like leptomeningeal tumor of childhood: a distinctive clinicopathologic entity | Q48391103 | ||
| Genetic alterations commonly found in diffusely infiltrating cerebral gliomas are rare or absent in pleomorphic xanthoastrocytomas | Q48425137 | ||
| Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas | Q48446962 | ||
| Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas | Q48465073 | ||
| IDH1 mutation in pediatric gliomas: has it a diagnostic and prognostic value? | Q48606060 | ||
| Low-grade astrocytoma: a decade of experience at St. Jude Children's Research Hospital | Q48651367 | ||
| Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. | Q48820061 | ||
| Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes | Q48872957 | ||
| Clinico-pathological features of pilomyxoid astrocytoma of the optic pathway | Q49215584 | ||
| Mutually exclusive mutations of KIT and RAS are associated with KIT mRNA expression and chromosomal instability in primary intracranial pure germinomas. | Q53071216 | ||
| Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors. | Q53287380 | ||
| Defining the molecular landscape of ependymomas. | Q53510508 | ||
| Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-κB signaling pathway. | Q55461138 | ||
| BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern. | Q55462093 | ||
| Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH. | Q55466873 | ||
| Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma. | Q55474092 | ||
| Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis | Q58001730 | ||
| Nonsense Mutation and Inactivation of SMARCA4 (BRG1) in an Atypical Teratoid/Rhabdoid Tumor Showing Retained SMARCB1 (INI1) Expression | Q58001757 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 159-172 | |
| P577 | publication date | 2016-11-10 | |
| P1433 | published in | Journal of Pathology | Q400296 |
| P1476 | title | Molecular pathology of paediatric central nervous system tumours | |
| P478 | volume | 241 |
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