| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NSMB.3371 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/nsmb.3371 |
| P932 | PMC publication ID | 5405867 |
| P698 | PubMed publication ID | 28165509 |
| P50 | author | Paul P Geurink | Q51751752 |
| Huib Ovaa | Q28320514 | ||
| P2093 | author name string | Günter Fritz | |
| Klaus-Peter Knobeloch | |||
| Paola Storici | |||
| Annika Röcker | |||
| Roya Tadayon | |||
| Sandra Hess | |||
| Marta S Semrau | |||
| Anja Basters | |||
| Katharina F Witting | |||
| P2860 | cites work | MultiBac: expanding the research toolbox for multiprotein complexes. | Q37966364 |
| IFNs, ISGylation and cancer: Cui prodest? | Q38036017 | ||
| Interferon-induced ISG15 pathway: an ongoing virus-host battle | Q38082061 | ||
| The antiviral activities of ISG15. | Q38149665 | ||
| The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchange | Q42028148 | ||
| Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane | Q42070422 | ||
| ISG15 uncut: Dissecting enzymatic and non-enzymatic functions of USP18 in vivo | Q42152834 | ||
| Ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) in host defense against heart failure in a mouse model of virus-induced cardiomyopathy | Q42197083 | ||
| Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin | Q42573161 | ||
| mHERC6 is the essential ISG15 E3 ligase in the murine system | Q42802538 | ||
| Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis. | Q45345094 | ||
| Automated unrestricted multigene recombineering for multiprotein complex production | Q47891788 | ||
| Baculovirus expression system for heterologous multiprotein complexes. | Q51575215 | ||
| Two ZnF-UBP domains in isopeptidase T (USP5). | Q55055597 | ||
| MultiBac: multigene baculovirus-based eukaryotic protein complex production | Q81131931 | ||
| Crystal structure of the interferon-induced ubiquitin-like protein ISG15 | Q81786381 | ||
| Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency | Q24294718 | ||
| Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme | Q24301649 | ||
| Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry | Q24303864 | ||
| Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification | Q24304218 | ||
| ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin | Q24317640 | ||
| UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity | Q24337310 | ||
| Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways | Q24531725 | ||
| Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein | Q24536345 | ||
| Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14 | Q24537053 | ||
| The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein | Q24562149 | ||
| Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation | Q24563471 | ||
| PHENIX: a comprehensive Python-based system for macromolecular structure solution | Q24654617 | ||
| Jalview Version 2--a multiple sequence alignment editor and analysis workbench | Q24655519 | ||
| ISG15 deficiency and increased viral resistance in humans but not mice | Q27317417 | ||
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | Q27640257 | ||
| Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21 | Q27667261 | ||
| Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase | Q27674789 | ||
| A Strategy for Modulation of Enzymes in the Ubiquitin System | Q27675727 | ||
| On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases | Q27676208 | ||
| A 2.2 Å resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding | Q27682011 | ||
| Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease | Q27683898 | ||
| XDS | Q27860472 | ||
| Protein production by auto-induction in high density shaking cultures | Q27860514 | ||
| REFMAC5 for the refinement of macromolecular crystal structures | Q27860905 | ||
| Phasercrystallographic software | Q27860930 | ||
| Dali server: conservation mapping in 3D | Q27860994 | ||
| Features and development of Coot | Q27861079 | ||
| UBP43 (USP18) specifically removes ISG15 from conjugated proteins | Q27863712 | ||
| Proteomic identification of proteins conjugated to ISG15 in mouse and human cells | Q27863897 | ||
| Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells | Q27863910 | ||
| HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets | Q27863927 | ||
| ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation. | Q27863932 | ||
| Breaking the chains: structure and function of the deubiquitinases | Q28131738 | ||
| Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8) | Q28268036 | ||
| A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14 | Q28359750 | ||
| Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15 | Q28505547 | ||
| Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome | Q30090228 | ||
| Screen for ISG15-crossreactive deubiquitinases | Q33291767 | ||
| Immunoregulatory properties of ISG15, an interferon-induced cytokine | Q33610088 | ||
| The ISG15 conjugation system broadly targets newly synthesized proteins: implications for the antiviral function of ISG15. | Q33919690 | ||
| ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus | Q33925311 | ||
| HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells | Q34137392 | ||
| ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis. | Q34148155 | ||
| Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 | Q34165581 | ||
| Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin | Q34396930 | ||
| Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance | Q34458906 | ||
| Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins | Q34551647 | ||
| Tricine-SDS-PAGE. | Q34615345 | ||
| Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation | Q35002436 | ||
| USP18 lack in microglia causes destructive interferonopathy of the mouse brain | Q35762623 | ||
| USP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms | Q35913320 | ||
| Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease | Q36923194 | ||
| USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex | Q37055514 | ||
| Emerging role of ISG15 in antiviral immunity | Q37800220 | ||
| P433 | issue | 3 | |
| P304 | page(s) | 270-278 | |
| P577 | publication date | 2017-02-06 | |
| P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
| P1476 | title | Structural basis of the specificity of USP18 toward ISG15. | |
| P478 | volume | 24 |
| Q40207077 | A Naturally Occurring Recombinant Enterovirus Expresses a Torovirus Deubiquitinase |
| Q59327241 | A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25 |
| Q100693199 | Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design |
| Q64888108 | An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes. |
| Q92233271 | Approaches for investigating the extracellular signaling function of ISG15 |
| Q50045539 | CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages. |
| Q64121205 | Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X |
| Q102211119 | Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity |
| Q92205463 | Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases |
| Q91576425 | Deubiquitinating enzymes (DUBs): DoUBle-edged swords in CNS autoimmunity |
| Q99591319 | Emerging Roles of USP18: From Biology to Pathophysiology |
| Q49990366 | Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target. |
| Q47444950 | Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor |
| Q47841496 | How USP18 deals with ISG15-modified proteins: structural basis for the specificity of the protease |
| Q88701533 | ISG15 in antiviral immunity and beyond |
| Q64127167 | ISG15: It's Complicated |
| Q40079195 | ISGylation - a key to lock the cell gates for preventing the spread of threats |
| Q49790187 | Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. |
| Q64103530 | MultiBac: Baculovirus-Mediated Multigene DNA Cargo Delivery in Insect and Mammalian Cells |
| Q47413440 | Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein |
| Q98162461 | Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity |
| Q92233313 | Profiling DUBs and Ubl-specific proteases with activity-based probes |
| Q90485218 | Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming |
| Q47171904 | Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades |
| Q59136645 | Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1 |
| Q89623181 | Strategies to Target ISG15 and USP18 Toward Therapeutic Applications |
| Q40101162 | The Role of Interferons in Inflammation and Inflammasome Activation |
| Q106996591 | The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery |
| Q58690927 | The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel |
| Q59329027 | USP18 - a multifunctional component in the interferon response |
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