review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Gaelle Le Friec | Q60487788 |
Claudia Kemper | Q73090566 | ||
P2093 | author name string | Simon Freeley | |
P2860 | cites work | Antigen presentation and T cell stimulation by dendritic cells | Q22255632 |
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue | Q24292702 | ||
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype | Q24293121 | ||
The CD46-Jagged1 interaction is critical for human TH1 immunity | Q24301407 | ||
CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes | Q24338598 | ||
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice | Q24604235 | ||
Posttranscriptional control of T cell effector function by aerobic glycolysis | Q24606942 | ||
Four viruses, two bacteria, and one receptor: membrane cofactor protein (CD46) as pathogens' magnet | Q24623803 | ||
Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes | Q24680369 | ||
Structure of the poly-C9 component of the complement membrane attack complex | Q28115911 | ||
Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma | Q28142956 | ||
Signal transduction through decay-accelerating factor. Interaction of glycosyl-phosphatidylinositol anchor and protein tyrosine kinases p56lck and p59fyn 1 | Q28188748 | ||
Defensins: antimicrobial peptides of innate immunity | Q28204453 | ||
The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74) | Q28214372 | ||
Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement | Q28237531 | ||
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response | Q28242527 | ||
Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency | Q28268386 | ||
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. | Q37241002 | ||
A novel "complement-metabolism-inflammasome axis" as a key regulator of immune cell effector function | Q37260702 | ||
Interaction between the coagulation and complement system | Q37331658 | ||
Functions of C5a receptors | Q37369597 | ||
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation | Q37397572 | ||
Arachidonate metabolism by human polymorphonuclear leukocytes stimulated by N-formyl-Met-Leu-Phe or complement component C5a is independent of phospholipase activation | Q37509006 | ||
Structure and function of the leukocyte adhesion molecules CD11/CD18. | Q37580454 | ||
The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis. | Q37627550 | ||
Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2 | Q37652278 | ||
Identification of an additional class of C3-binding membrane proteins of human peripheral blood leukocytes and cell lines | Q37677073 | ||
Specialized roles for cysteine cathepsins in health and disease. | Q37797839 | ||
The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain | Q28285921 | ||
The internal thioester and the covalent binding properties of the complement proteins C3 and C4 | Q28304143 | ||
Complement and its receptors: new insights into human disease | Q28307316 | ||
The receptor NLRP3 is a transcriptional regulator of TH2 differentiation | Q28512758 | ||
Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection | Q28817811 | ||
Innate or adaptive immunity? The example of natural killer cells | Q29615106 | ||
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation | Q29615178 | ||
Complement: a key system for immune surveillance and homeostasis | Q29615484 | ||
Activation and regulation of the inflammasomes | Q29615664 | ||
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex | Q29617214 | ||
Physiological roles of mitochondrial reactive oxygen species | Q29620297 | ||
Generation of anaphylatoxins by human beta-tryptase from C3, C4, and C5 | Q30439751 | ||
Complement regulators and inhibitory proteins | Q33386110 | ||
Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses | Q33423703 | ||
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells | Q33570304 | ||
Variable morbidity in alagille syndrome: a review of 43 cases | Q33747368 | ||
The dynamic processing of CD46 intracellular domains provides a molecular rheostat for T cell activation | Q33809500 | ||
CR3: a general purpose adhesion-recognition receptor essential for innate immunity | Q33887451 | ||
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. | Q34000160 | ||
Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells. | Q34086998 | ||
A functional interaction between CD46 and DLG4: a role for DLG4 in epithelial polarization | Q34102432 | ||
Cellular response to oxidative stress: signaling for suicide and survival | Q34138566 | ||
Role of Complement in Induction of the Allergic Response | Q34212341 | ||
Intracellular sensing of complement C3 activates cell autonomous immunity. | Q34231523 | ||
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation | Q34242691 | ||
Complement regulatory protein CD46 protects against choroidal neovascularization in mice | Q34299745 | ||
IL-7 is essential for homeostatic control of T cell metabolism in vivo | Q34307992 | ||
Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. | Q34550742 | ||
C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells | Q34579613 | ||
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells | Q34760201 | ||
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy | Q34836376 | ||
C5a-induced gene expression in human umbilical vein endothelial cells | Q35094695 | ||
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells | Q35102340 | ||
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis | Q35127765 | ||
NLRP3 inflammasomes link inflammation and metabolic disease | Q35151726 | ||
Mice Deficient in Complement Receptors 1 and 2 Lack a Tissue Injury-Inducing Subset of the Natural Antibody Repertoire | Q57331400 | ||
Local synthesis of complement component C3 regulates acute renal transplant rejection | Q57369617 | ||
Generation of C5a in the absence of C3: a new complement activation pathway | Q58523865 | ||
Complement protein C1q induces maturation of human dendritic cells | Q60861601 | ||
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs | Q61441031 | ||
Brief Report: Complement C5a Promotes Human Embryonic Stem Cell Pluripotency in the Absence of FGF2 | Q63916944 | ||
Purification and partial characterization of human and porcine C3a anaphylatoxin | Q67506949 | ||
Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes | Q67701907 | ||
Chemotaxis by mouse macrophage cell lines | Q70765924 | ||
Increased expression of C3b receptors on polymorphonuclear leukocytes induced by chemotactic factors and by purification procedures | Q71726410 | ||
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines | Q71746654 | ||
Activation of human neutrophils by C3a and C5A. Comparison of the effects on shape changes, chemotaxis, secretion, and respiratory burst | Q72020363 | ||
C3a activates reactive oxygen radical species production and intracellular calcium transients in human eosinophils | Q72285861 | ||
C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins | Q72454839 | ||
Characterization of accessory molecules in murine lung dendritic cell function: roles for CD80, CD86, CD54, and CD40L | Q73155746 | ||
Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells | Q73709052 | ||
Complement c3a and c5a induce different signal transduction cascades in endothelial cells | Q74583305 | ||
A critical role for complement in maintenance of self-tolerance | Q77658426 | ||
Alterations in C3 activation and binding caused by phosphorylation by a casein kinase released from activated human platelets | Q77841687 | ||
A role for mammalian target of rapamycin in regulating T cell activation versus anergy | Q79717975 | ||
Local production and activation of complement up-regulates the allostimulatory function of dendritic cells through C3a-C3aR interaction | Q80140686 | ||
Complement--tapping into new sites and effector systems | Q85959086 | ||
The role of complement in the diagnosis and management of allergic rhinitis and allergic asthma | Q37822299 | ||
Sensing disease and danger: a survey of vertebrate PRRs and their origins | Q37829490 | ||
Granzyme B: a new crossroad of complement and apoptosis | Q37938946 | ||
IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis | Q38007051 | ||
Biochemical regulation of the inflammasome | Q38017287 | ||
Regulation of humoral immunity by complement | Q38037801 | ||
Metabolism of inflammation limited by AMPK and pseudo-starvation | Q38074586 | ||
The role of complement in CD4⁺ T cell homeostasis and effector functions | Q38110968 | ||
Primary complement C5 deficiencies - molecular characterization and clinical review of two families | Q38112539 | ||
Training innate immunity: the changing concept of immunological memory in innate host defence | Q38122699 | ||
Mechanisms of NOD-like receptor-associated inflammasome activation | Q38140207 | ||
CD46: the 'multitasker' of complement proteins. | Q38152144 | ||
NLRP3 at the interface of metabolism and inflammation. | Q38423371 | ||
Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor. | Q39032467 | ||
Cytokines in inflammatory bowel disease | Q39206254 | ||
Release of histamine from rat mast cells by the complement peptides C3a and C5a. | Q39327002 | ||
The gut microbiota modulates host energy and lipid metabolism in mice | Q39993460 | ||
Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form | Q40526230 | ||
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development | Q40760682 | ||
Functional modulation of human macrophages through CD46 (measles virus receptor): production of IL-12 p40 and nitric oxide in association with recruitment of protein-tyrosine phosphatase SHP-1 to CD46. | Q40846624 | ||
Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation | Q40875377 | ||
Membrane cofactor protein (MCP; CD46): isoform-specific tyrosine phosphorylation | Q40902413 | ||
Complement drives Th17 cell differentiation and triggers autoimmune arthritis. | Q40952250 | ||
C3a and C5a stimulate chemotaxis of human mast cells | Q41115852 | ||
Extrahepatic complement biosynthesis: where, when and why? | Q41331539 | ||
Inherited complement C3 deficiency: a defect in C3 secretion | Q41456840 | ||
Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21). | Q41780931 | ||
Role of complement in induction of antibody production in vivo. Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses | Q41921458 | ||
Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation. | Q41957299 | ||
Functional analysis of C5a effector responses in vitro and in vivo | Q42241097 | ||
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma | Q42423633 | ||
Autophagy induction by the pathogen receptor CD46. | Q42461485 | ||
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment | Q42593305 | ||
Human complement C3 deficiency: Th1 induction requires T cell-derived complement C3a and CD46 activation. | Q43630649 | ||
Histamine-induced inhibition of normal human basophil chemotaxis to C5a | Q43966141 | ||
Renal expression of the C3a receptor and functional responses of primary human proximal tubular epithelial cells | Q45050747 | ||
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection | Q45733086 | ||
Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro. | Q46010319 | ||
ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy | Q46577083 | ||
C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. | Q47954758 | ||
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. | Q50959906 | ||
Human C3 deficiency associated with impairments in dendritic cell differentiation, memory B cells, and regulatory T cells. | Q51961907 | ||
Factor VII-activating protease is activated in multiple trauma patients and generates anaphylatoxin C5a. | Q53669943 | ||
Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS. | Q54615593 | ||
Dendritic cell function in allostimulation is modulated by C5aR signaling. | Q54712683 | ||
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies | Q57089602 | ||
Organ-specific contribution to circulating C7 levels by the bone marrow and liver in humans | Q57089607 | ||
Extrahepatic secreted complement C3 contributes to circulating C3 levels in humans | Q57089621 | ||
Tissue-specific expression of CD46 isoforms | Q57272519 | ||
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation | Q35242438 | ||
The evolution of mouse and human complement C3-binding proteins: divergence of form but conservation of function | Q35326510 | ||
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. | Q35350543 | ||
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. | Q35404457 | ||
Membrane cofactor protein | Q35483434 | ||
Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. | Q35603188 | ||
Regulation of JAK-STAT signalling in the immune system | Q35605437 | ||
Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo | Q35642856 | ||
The complement system in B cell regulation | Q35781836 | ||
Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18) | Q35868877 | ||
C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity | Q35884221 | ||
The complement system in regulation of adaptive immunity | Q35904390 | ||
A novel role for CD46 in wound repair | Q35928410 | ||
T-cell stimulation and regulation: with complements from CD46. | Q36232659 | ||
The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement | Q36268987 | ||
Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes | Q36269256 | ||
Receptors for complement of leukocytes | Q36269375 | ||
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death | Q36365164 | ||
Decay-accelerating factor modulates induction of T cell immunity | Q36403001 | ||
The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo | Q36403243 | ||
IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival | Q36445850 | ||
Complement regulatory protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis. | Q36471905 | ||
The role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow. | Q36558411 | ||
Self, non-self, and danger: a complementary view | Q36558427 | ||
Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells | Q36603536 | ||
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. | Q36639793 | ||
T-cell regulation: with complements from innate immunity | Q36684909 | ||
Metabolic regulation of T lymphocytes | Q36711431 | ||
Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy | Q36723728 | ||
Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis | Q36843709 | ||
The role of the complement anaphylatoxins in the recruitment of eosinophils | Q37015015 | ||
CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulation | Q37088454 | ||
Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production | Q37106187 | ||
Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection | Q37106399 | ||
P433 | issue | 1 | |
P304 | page(s) | 16-32 | |
P577 | publication date | 2016-11-01 | |
P1433 | published in | Immunological Reviews | Q15724582 |
P1476 | title | The "ins and outs" of complement-driven immune responses | |
P478 | volume | 274 |
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Q39246952 | Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery. |
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Q50049007 | Complement in cancer: untangling an intricate relationship. |
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Q39135367 | Complement's hidden arsenal: New insights and novel functions inside the cell. |
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