Clinical and regulatory considerations in pharmacogenetic testing.

scientific article published on December 2016

Clinical and regulatory considerations in pharmacogenetic testing. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2146/AJHP160476
P932PMC publication ID6462817
P698PubMed publication ID27864207

P2093author name stringRobert N Schuck
Michael Pacanowski
Elizabeth Marek
Hobart Rogers
P2860cites workClinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosingQ24632749
Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesQ24632927
Genetic variations in HLA-B region and hypersensitivity reactions to abacavirQ28214097
Medical genetics: a marker for Stevens-Johnson syndromeQ28254047
Individualized medicine from prewomb to tombQ29525070
Cancer statistics, 2016Q29547383
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprineQ33336860
Estimation of the warfarin dose with clinical and pharmacogenetic dataQ33410725
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locusQ33882066
Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavirQ33956146
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavirQ34117815
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in EuropeansQ34172669
2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and InterventiQ34231154
Severe adverse cutaneous reactions to drugsQ34314152
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysisQ34624862
HLA-B*5701 screening for hypersensitivity to abacavirQ34747145
Clinical pharmacology and pharmacogenetics of thiopurinesQ34782066
Genetic determinants of response to clopidogrel and cardiovascular eventsQ34910210
Cytochrome p-450 polymorphisms and response to clopidogrelQ34910228
American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapyQ34935716
Genomics and drug responseQ35252277
Anticonvulsant hypersensitivity syndrome. In vitro assessment of riskQ35594031
Personalizing medicine with clinical pharmacogeneticsQ35791989
Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosingQ36029478
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarinQ37196787
A pharmacogenetic versus a clinical algorithm for warfarin dosingQ37616712
Thiopurine S-methyltransferase (TPMT) assessment prior to starting thiopurine drug treatment; a pharmacogenomic test whose time has comeQ37721661
Systematic review: Anti-epidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancerQ37825721
Pharmacogenetic screening of carbamazepine-induced severe cutaneous allergic reactions.Q37908444
HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic reviewQ38058271
Carbamazepine-induced toxic effects and HLA-B*1502 screening in TaiwanQ39268755
Biomarkers to improve the benefit/risk balance for approved therapeutics: a US FDA perspective on personalized medicine.Q39822900
Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort studyQ43121603
Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancerQ43292375
Effects of a HLA-B*15:02 screening policy on antiepileptic drug use and severe skin reactionsQ45893637
A randomized trial of genotype-guided dosing of warfarin.Q51140132
Primary care guidelines for the management of persons infected with HIV: 2013 update by the HIV medicine association of the Infectious Diseases Society of America.Q51859231
Differential effects of targeted disruption of thiopurine methyltransferase on mercaptopurine and thioguanine pharmacodynamics.Q52579212
Enhanced proteasomal degradation of mutant human thiopurine S-methyltransferase (TPMT) in mammalian cells: mechanism for TPMT protein deficiency inherited by TPMT*2, TPMT*3A, TPMT*3B or TPMT*3CQ73257107
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)1999-2006
P577publication date2016-12-01
P1433published inAmerican Journal of Health-System PharmacyQ15754037
P1476titleClinical and regulatory considerations in pharmacogenetic testing
P478volume73

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cites work (P2860)
Q92102522Integrating pharmacogenetic testing into primary care
Q91582436Pharmacogenomic biomarker information differences between drug labels in the United States and Hungary: implementation from medical practitioner view

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