Lessons from babies: inducing HIV-1 broadly neutralizing antibodies

scientific article published on June 2014

Lessons from babies: inducing HIV-1 broadly neutralizing antibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM.3598
P932PMC publication ID4793272
P698PubMed publication ID24901564

P50authorBarton HaynesQ4865631
Georgia D. TomarasQ63663866
P2860cites workPolyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individualsQ24635002
HIV‐1 neutralizing antibodies: understanding nature's pathwaysQ27000480
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virusQ27644501
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodiesQ27644515
Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 NeutralizationQ27677117
Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope SpikeQ27683540
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimersQ27683553
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralizationQ27684578
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine targetQ29547347
Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infectionQ33702217
Early development of broadly neutralizing antibodies in HIV-1-infected infantsQ33764917
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individualsQ34962766
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infectionQ35076717
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestorsQ35382871
Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escapeQ36388754
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infectionQ37033294
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimersQ39001126
Opening Fronts in HIV Vaccine Development: Tracking the development of broadly neutralizing antibodiesQ50617948
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)583-585
P577publication date2014-06-01
P1433published inNature medicineQ1633234
P1476titleLessons from babies: inducing HIV-1 broadly neutralizing antibodies
P478volume20

Reverse relations

cites work (P2860)
Q35728947HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
Q38534943Prospects for a globally effective HIV-1 vaccine

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