Prospects for a globally effective HIV-1 vaccine

scientific article published on 19 June 2015

Prospects for a globally effective HIV-1 vaccine is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2015.03.059
P698PubMed publication ID26100921
P5875ResearchGate publication ID279065640

P50authorMerlin L RobbQ56871310
Jerome H KimQ56871312
Jean-Louis ExclerQ59690019
P2860cites workDesign and pre-clinical evaluation of a universal HIV-1 vaccineQ21092234
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Which Antibody Functions are Important for an HIV Vaccine?Q33772637
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Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2Q34298408
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Immune clearance of highly pathogenic SIV infectionQ34370314
Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trialQ34374835
HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaquesQ34388606
Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infectionQ34402934
Challenges in the design of a T cell vaccine in the context of HIV-1 diversityQ34423446
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.Q34434854
Heterologous prime-boost regimens using rAd35 and rMVA vectors elicit stronger cellular immune responses to HIV proteins than homologous regimensQ34438489
Lessons from the RV144 Thai phase III HIV-1 vaccine trial and the search for correlates of protectionQ34444625
Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trialQ34562259
Accelerating HIV-1 Vaccine Efficacy TrialsQ34580725
Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c miceQ34592940
Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodiesQ34593647
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivoQ34593860
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibodyQ34630446
Neutralizing antibody responses in macaques induced by human immunodeficiency virus type 1 monovalent or trivalent envelope glycoproteinsQ34637968
Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trialQ34648825
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Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responsesQ34802680
HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.Q34915786
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individualsQ34962766
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccineQ35009558
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-LQ35012462
An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: results from a randomized placebo-controlled trial (the Step study)Q35057732
A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual componentQ35076748
A native-like SOSIP.664 trimer based on an HIV-1 subtype B env geneQ35110976
Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like propertiesQ35540033
Promising prevention approaches: tenofovir gel and prophylactic use of antiretroviral medicationsQ35619304
Antibody-based protection against HIV infection by vectored immunoprophylaxisQ35658856
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeysQ35729899
A critical question for HIV vaccine development: which antibodies to induce?Q35783015
Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaQ35826525
Nomenclature for immune correlates of protection after vaccinationQ35948780
A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challengeQ36024470
HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.Q36132728
Safety and efficacy of the HVTN 503/Phambili study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b studyQ36158727
Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene familyQ36363231
Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivoQ36414891
Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144.Q36489415
P407language of work or nameEnglishQ1860
P304page(s)D4-12
P577publication date2015-06-19
P1433published inVaccineQ7907941
P1476titleProspects for a globally effective HIV-1 vaccine
P478volume33 Suppl 4

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cites work (P2860)
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