KRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers

scientific article published on 13 December 2016

KRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4137/JCM.S40549
P932PMC publication ID5156551
P698PubMed publication ID28008299

P2093author name stringToshiyuki Mori
Masanori Sugiyama
Takashi Watanabe
Satsuki Matsushima
Junji Furuse
Yasuo Ohkura
Masaaki Yokoyama
Hiroaki Ohnishi
Kouki Ohtsuka
P2860cites workPredictive and prognostic value of KRAS mutations in metastatic colorectal cancer patients treated with cetuximab: a meta-analysis of 22 studiesQ37767871
Chemotherapy for the biliary tract cancers: moving toward improved survival timeQ37983498
Toward personalized treatment of advanced biliary tract cancersQ38030656
A comparison of trends in the incidence of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in the United StatesQ38467833
KRAS and PIK3CA but not BRAF genes are frequently mutated in Chinese cholangiocarcinoma patientsQ39820471
Report of the 17th Nationwide Follow-up Survey of Primary Liver Cancer in JapanQ40196680
A simple and sensitive method for detecting major mutations within the tyrosine kinase domain of the epidermal growth factor receptor gene in non-small-cell lung carcinomaQ40266820
Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinomaQ43005729
FBXW7/hCDC4 is a general tumor suppressor in human cancer.Q45345209
Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancersQ46488823
Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?Q54361260
Genetic alterations in gallbladder adenoma, dysplasia and carcinomaQ74033242
Histological and genetic changes in malignant transformation of gallbladder adenomaQ78096954
K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in ChinaQ78358414
Biliary tract cancer treatment: 5,584 results from the Biliary Tract Cancer Statistics Registry from 1998 to 2004 in JapanQ83097384
PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysisQ26992267
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodiesQ27851465
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysisQ27851573
TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patientsQ33179641
Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomasQ33750719
Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in ≥ 2 line cetuximab-based therapy of colorectal cancer patientsQ33809458
Mutational profiling reveals PIK3CA mutations in gallbladder carcinomaQ33814916
Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancerQ34094717
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.Q34554584
PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitorsQ34769343
Best Practice No 176: Updated recommendations for HER2 testing in the UKQ35587451
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutationsQ35808438
Gallbladder cancer worldwide: geographical distribution and risk factorsQ36362499
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancerQ37274280
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancerQ37287501
EGFR and HER2 expression in advanced biliary tract cancerQ37362858
Genetics of biliary tract cancers and emerging targeted therapiesQ37765099
P921main subjectbiomarkerQ864574
P304page(s)33-39
P577publication date2016-12-13
P1433published inJapanese clinical medicineQ27724884
P1476titleKRAS Mutation as a Potential Prognostic Biomarker of Biliary Tract Cancers
P478volume7

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