Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells

scientific article published on August 1991

Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/INTIMM/3.8.761
P698PubMed publication ID1911545

P2093author name stringHarada S
Sato S
Morita M
Inoko H
Igarashi H
Sugimoto M
Maruyama I
Kannagi M
Kidokoro M
Kuwashima G
P433issue8
P921main subjectleukemiaQ29496
cytotoxicityQ246181
Human T-lymphotropic virus 1Q1280388
P304page(s)761-767
P577publication date1991-08-01
P1433published inInternational ImmunologyQ15710043
P1476titlePredominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cells
P478volume3

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cites work (P2860)
Q404758356 Human T-cell leukaemia virus
Q40116023A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax301-309-Specific Cytotoxic T Cells in HLA-A24:02-Positive Asymptomatic Carriers and Adult T-Cell Leukemia/Lymphoma Patients
Q41397919A rat model of HTLV-I infection: development of chronic progressive myeloneuropathy in seropositive WKAH rats and related apoptosis
Q39704609APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo
Q39574730ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells
Q45362124Advantage of higher-avidity CTL specific for Tax against human T-lymphotropic virus-1 infected cells and tumors
Q39875392Among all human T-cell leukemia virus type 1 proteins, tax, polymerase, and envelope proteins are predicted as preferential targets for the HLA-A2-restricted cytotoxic T-cell response.
Q36967203Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Q33245942Antibody responses associated with the graft-versus-leukemia effect in adult T-cell leukemia.
Q64912641Association Between HTLV-1 Genotypes and Risk of HAM/TSP.
Q36548660Astrocyte-specific expression of human T-cell lymphotropic virus type 1 (HTLV-1) Tax: induction of tumor necrosis factor alpha and susceptibility to lysis by CD8+ HTLV-1-specific cytotoxic T cells
Q36448106Atomic Coordination Reflects Peptide Immunogenicity.
Q37945242Cell Surface Markers in HTLV-1 Pathogenesis
Q37069833Cellular Immune Responses against Simian T-Lymphotropic Virus Type 1 Target Tax in Infected Baboons
Q36254893Cellular immune response to HTLV-1.
Q33733750Chronic dacryosialadenitis in HTLV I associated myelopathy
Q36633226Circulating anti-Tax cytotoxic T lymphocytes from human T-cell leukemia virus type I-infected people, with and without tropical spastic paraparesis, recognize multiple epitopes simultaneously.
Q34156338Clonal expansion of CD8+ cytotoxic T lymphocytes against human T cell lymphotropic virus type I (HTLV-I) genome products in HTLV-I-associated myelopathy/tropical spastic paraparesis patients
Q35120139Clonality of HTLV-2 in natural infection
Q36641900Complete nucleotide sequence of a highly divergent human T-cell leukemia (lymphotropic) virus type I (HTLV-I) variant from melanesia: genetic and phylogenetic relationship to HTLV-I strains from other geographical regions
Q40287235DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells
Q39292402De novo human T-cell leukemia virus type 1 infection of human lymphocytes in NOD-SCID, common gamma-chain knockout mice
Q44718738Defective human T-lymphotropic virus type 1 provirus in asymptomatic carriers
Q42219339Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice
Q33795171Development of human T-cell leukemia virus type 1-transformed tumors in rats following suppression of T-cell immunity by CD80 and CD86 blockade
Q37827194Double control systems for human T‐cell leukemia virus type 1 by innate and acquired immunity
Q41129466Dual infection of rabbits with human T cell lymphotropic virus types I and II.
Q47598074Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.
Q45755372Epitope Mapping of Bovine Leukemia Virus Transactivator Protein Tax
Q33816840Establishment of a seronegative human T-cell leukemia virus type 1 (HTLV-1) carrier state in rats inoculated with a syngeneic HTLV-1-immortalized T-cell line preferentially expressing Tax.
Q35891748Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide
Q34756170Expansion of human T-cell leukemia virus type 1 (HTLV-1) reservoir in orally infected rats: inverse correlation with HTLV-1-specific cellular immune response
Q34649734Genome-wide determinants of proviral targeting, clonal abundance and expression in natural HTLV-1 infection
Q42228781HBZ and its roles in HTLV-1 oncogenesis
Q36452983HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy
Q33707746HLA class I binding of HBZ determines outcome in HTLV-1 infection
Q54242431HTLV-1 Alters T Cells for Viral Persistence and Transmission.
Q90733114HTLV-1 as a Model for Virus and Host Coordinated Immunoediting
Q37430368HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling
Q38169485HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection
Q36112549HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals
Q34316662HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP.
Q45096240HTLV-1-associated myelopathy/tropical spastic paraparesis
Q34270849HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells
Q54699187HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy.
Q39149923HTLV-I specific IFN-gamma+ CD8+ lymphocytes correlate with the proviral load in peripheral blood of infected individuals
Q37014310High frequency of CD4+FoxP3+ cells in HTLV-1 infection: inverse correlation with HTLV-1-specific CTL response
Q36361794High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease
Q47548079How Does HTLV-1 Undergo Oncogene-Dependent Replication Despite a Strong Immune Response?
Q34683956Human T cell leukemia virus type 1 (HTLV-1) and oncogene or oncomiR addiction?
Q91967437Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Upregulates the Expression of ICAM-1 To Facilitate HTLV-1 Infection
Q40046615Human T-cell leukaemia virus type 1: parasitism and pathogenesis
Q37142785Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination
Q24805664Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)
Q99711033Human T-cell lymphotropic virus HBZ and tax mRNA expression are associated with specific clinicopathological features in adult T-cell leukemia/lymphoma
Q100311468Human T-cell lymphotropic virus type-1: a lifelong persistent infection, yet never truly silent
Q35611766Human T-lymphotropic virus type 1 (HTLV-1): persistence and immune control
Q45443442Human T-lymphotropic virus, type 1, tax protein triggers microtubule reorientation in the virological synapse
Q38906679IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian population.
Q40041190IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways.
Q90639358IL-2/IL-2 Receptor Pathway Plays a Crucial Role in the Growth and Malignant Transformation of HTLV-1-Infected T Cells to Develop Adult T-Cell Leukemia
Q33908704Identification of two new HLA-A*1101-restricted tax epitopes recognized by cytotoxic T lymphocytes in an adult T-cell leukemia patient after hematopoietic stem cell transplantation
Q33651831Immunogenetics and the Pathological Mechanisms of Human T-Cell Leukemia VirusType 1- (HTLV-1-)Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
Q36944303Immunologic control of human T-cell leukemia virus type I and adult T-cell leukemia
Q38056376Immunological homeostasis of the eye
Q36422111Immunopathogenesis of human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: recent perspectives
Q34203309Immunopathological mechanisms of human T cell lymphotropic virus type 1 (HTLV-I) uveitis. Detection of HTLV-I-infected T cells in the eye and their constitutive cytokine production
Q92787350Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL
Q36944299Implication of the HTLV-I bZIP factor gene in the leukemogenesis of adult T-cell leukemia
Q41403895In vitro induction of cytotoxic T lymphocytes against HTLV-I-infected T-cells from adult T-cell leukemia patients, asymptomatic HTLV-I carriers and seronegative healthy donors
Q40267146In vitro peptide immunization of target tax protein human T-cell leukemia virus type 1-specific CD4+ helper T lymphocytes
Q39200260In vitro virus propagation and high cellular responsiveness to the infected cells in patients with HTLV-I-associated myelopathy (HAM/TSP).
Q39422572Increased levels of soluble Fas ligand in CSF of rapidly progressive HTLV-1-associated myelopathy/tropical spastic paraparesis patients
Q35909704Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax.
Q35892641Induction of tumor necrosis factor alpha in human neuronal cells by extracellular human T-cell lymphotropic virus type 1 Tax
Q38264568Integration site and clonal expansion in human chronic retroviral infection and gene therapy.
Q39815291Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-1.
Q55240180Involvement of granulocyte colony-stimulating factor in proliferation of adult T-cell leukemia cells.
Q41723007Is There a Role for HTLV-1-Specific CTL in Adult T-Cell Leukemia/Lymphoma?
Q35611774Leukemogenesis of adult T-cell leukemia
Q45710708Loss of the ex vivo but not the reinducible CD8+ T-cell response to Tax in human T-cell leukemia virus type 1-infected patients with adult T-cell leukemia/lymphoma
Q26801294Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence
Q37266106Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1
Q34332433Mouse model for the equilibration interaction between the host immune system and human T-cell leukemia virus type 1 gene expression
Q38128799Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis
Q38032236New insight into the oncogenic mechanism of the retroviral oncoprotein Tax
Q35836191Novel CD8(+) cytotoxic T cell epitopes in bovine leukemia virus with cattle.
Q92381563Novel Interactions between the Human T-Cell Leukemia Virus Type 1 Antisense Protein HBZ and the SWI/SNF Chromatin Remodeling Family: Implications for Viral Life Cycle
Q47578584Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development
Q33783833Oral Administration of Human T-Cell Leukemia Virus Type 1 Induces Immune Unresponsiveness with Persistent Infection in Adult Rats
Q39182964Potential Contribution of a Novel Tax Epitope–Specific CD4+ T Cells to Graft-versus-Tax Effect in Adult T Cell Leukemia Patients after Allogeneic Hematopoietic Stem Cell Transplantation
Q39124766Predominant expression of Fas ligand mRNA in CD8+ T lymphocytes in patients with HTLV-1 associated myelopathy
Q33811681Prevention of adult T-cell leukemia-like lymphoproliferative disease in rats by adoptively transferred T cells from a donor immunized with human T-cell leukemia virus type 1 Tax-coding DNA vaccine
Q35067468Quantum chemical calculations predict biological function: the case of T cell receptor interaction with a peptide/MHC class I.
Q35023802Reduction of human T-cell leukemia virus type 1 (HTLV-1) proviral loads in rats orally infected with HTLV-1 by reimmunization with HTLV-1-infected cells
Q33956264Regression of human T-cell leukemia virus type I (HTLV-I)-associated lymphomas in a rat model: peptide-induced T-cell immunity.
Q38262353Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway
Q37093004Repression of tax expression is associated both with resistance of human T-cell leukemia virus type 1-infected T cells to killing by tax-specific cytotoxic T lymphocytes and with impaired tumorigenicity in a rat model
Q26774352Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases
Q47550200Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells
Q37583516Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding
Q39138338Stromal cell-mediated suppression of human T-cell leukemia virus type 1 expression in vitro and in vivo by type I interferon
Q39119691Target epitope in the Tax protein of human T-cell leukemia virus type I recognized by class I major histocompatibility complex-restricted cytotoxic T cells
Q39147176Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders.
Q53160634Tax is a potential molecular target for immunotherapy of adult T-cell leukemia/lymphoma
Q37317982The HBZ gene, a key player in HTLV-1 pathogenesis
Q42267172The HTLV-1 HBZ protein inhibits cyclin D1 expression through interacting with the cellular transcription factor CREB.
Q39377294The Impact of Immune Response on HTLV-I in HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)
Q26768630The Role of HBZ in HTLV-1-Induced Oncogenesis
Q39218366The combination of IκB kinase β inhibitor and everolimus modulates expression of interleukin‐10 in human T‐cell lymphotropic virus type‐1‐infected T cells
Q36150424The coordination of unprotonated peptide tertiary structure as a metric of pMHC-TCR functional avidity.
Q33971004The immune response to HTLV-I.
Q39119670The roles of acquired and innate immunity in human T-cell leukemia virus type 1-mediated diseases
Q26744327Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 Provirus
Q35214398Tumor-associated antigens: from discovery to immunity
Q42488942Up-regulation of human T lymphotropic virus type 1 (HTLV-1) tax/rex mRNA in infected lung tissues
Q38100771Virological and immunological mechanisms in the pathogenesis of human T‐cell leukemia virus type 1
Q39879902cis-Acting inhibitory elements within the pol-env region of human T-cell leukemia virus type 1 possibly involved in viral persistence

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