ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells

scientific article published on 17 March 2011

ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1041937359
P356DOI10.1186/1742-4690-8-19
P932PMC publication ID3068935
P698PubMed publication ID21414204
P5875ResearchGate publication ID50418994

P50authorJun-ichirou YasunagaQ55270267
Masao MatsuokaQ38359671
Yorifumi SatouQ39704611
P2093author name stringKoichi Ohshima
Keita Hagiya
P2860cites workATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoformsQ24305500
Cell cycle, CDKs and cancer: a changing paradigmQ24314465
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationQ28257025
Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferationQ28572315
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaQ29615115
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cellsQ40584291
p53 stabilization and functional impairment in the absence of genetic mutation or the alteration of the p14(ARF)-MDM2 loop in ex vivo and cultured adult T-cell leukemia/lymphoma cellsQ40874341
Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding siteQ40937426
The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activityQ42446546
Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells.Q42508208
Human T-cell leukemia virus minus strand transcription in infected T-cellsQ42639581
Transcription factor ATF3 partially transforms chick embryo fibroblasts by promoting growth factor-independent proliferation.Q43583446
HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun proteinQ45183642
Cdc2-cyclin E complexes regulate the G1/S phase transitionQ46592665
A potential dichotomous role of ATF3, an adaptive-response gene, in cancer developmentQ53327858
ATF3 regulates the stability of p53: a link to cancerQ53626549
Structural and functional analysis of oncogenes and tumor suppressor genes in adult T-cell leukemia/lymphoma shows frequent p53 mutationsQ54376782
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathwayQ58211826
Mutations of the p53 gene in adult T-cell leukemiaQ67726300
p53 gene mutation and loss of heterozygosity are associated with increased risk of disease progression in adult T cell leukemiaQ72172265
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathwayQ81358751
HBZ interacts with JunD and stimulates its transcriptional activityQ33292275
ATF3 and stress responses.Q33706914
Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.Q33800021
The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasisQ34085639
Adult T-cell leukemia: clinical and hematologic features of 16 casesQ34162412
HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cellsQ34270849
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the diseaseQ34274473
Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human seraQ34276501
The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcriptionQ34350825
ATF3 gene. Genomic organization, promoter, and regulationQ34372871
Cyclin E2, the cycle continuesQ34537668
Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription.Q35635372
The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.Q36063657
Functional inactivation of p53 by human T-cell leukemia virus type 1 Tax protein: mechanisms and clinical implicationsQ36322573
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformationQ36769835
Human T-cell leukemia virus type I induces adult T-cell leukemia: from clinical aspects to molecular mechanismsQ36771229
Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferationQ36948607
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)Q37122656
Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitinationQ37142785
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.Q38313431
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3), which promotes viability of Hodgkin/Reed-Sternberg cellsQ38319231
Predominant recognition of human T cell leukemia virus type I (HTLV-I) pX gene products by human CD8+ cytotoxic T cells directed against HTLV-I-infected cellsQ39119695
APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivoQ39704609
Testican 3 expression in adult T-cell leukemiaQ39895306
Differential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cellsQ39896710
Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB.Q39907748
Transcriptional control of spliced and unspliced human T-cell leukemia virus type 1 bZIP factor (HBZ) geneQ39957576
A unique enhancer element for the trans activator (p40tax) of human T-cell leukemia virus type I that is distinct from cyclic AMP- and 12-O-tetradecanoylphorbol-13-acetate-responsive elements.Q40116375
The expression of transcription factor activating transcription factor 3 in the human prostate and its regulation by androgen in prostate cancerQ40309048
A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localizationQ40317377
Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitinationQ40413949
P921main subjectleukemiaQ29496
Human T-lymphotropic virus 1Q1280388
T-cell leukemiaQ7667895
P304page(s)19
P577publication date2011-03-17
P1433published inRetrovirologyQ15793508
P1476titleATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells
P478volume8

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cites work (P2860)
Q39162894A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation
Q34359754Ascorbic acid has superior ex vivo antiproliferative, cell death-inducing and immunomodulatory effects over IFN-α in HTLV-1-associated myelopathy
Q36890570CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.
Q56979456Cardiac Fibroblast-Specific Activating Transcription Factor 3 Promotes Myocardial Repair after Myocardial Infarction
Q92480985Comparative virology of HTLV-1 and HTLV-2
Q39792197Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy
Q42219339Development of T cell lymphoma in HTLV-1 bZIP factor and Tax double transgenic mice
Q42660338Diversity matters in scientific publishing
Q38947647Expression patterns of the activator protein-1 (AP-1) family members in lymphoid neoplasms.
Q26774369From Immunodeficiency to Humanization: The Contribution of Mouse Models to Explore HTLV-1 Leukemogenesis
Q36694078Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis
Q37076685Functional comparison of antisense proteins of HTLV-1 and HTLV-2 in viral pathogenesis
Q34749285Gene Expression Changes under Cyclic Mechanical Stretching in Rat Retinal Glial (Müller) Cells
Q42228781HBZ and its roles in HTLV-1 oncogenesis
Q40307719HBZ-mediated shift of JunD from growth suppressor to tumor promoter in leukemic cells by inhibition of ribosomal protein S25 expression.
Q52728051HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role
Q47221371HTLV-1 HBZ Viral Protein: A Key Player in HTLV-1 Mediated Diseases
Q42818886HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm
Q90733114HTLV-1 as a Model for Virus and Host Coordinated Immunoediting
Q36238411HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors
Q39263944HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells
Q37430368HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling
Q41921241HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia.
Q92501478HTLV-1 bZIP factor: the key viral gene for pathogenesis
Q33647780High-Amylose Resistant Starch Increases Hormones and Improves Structure and Function of the Gastrointestinal Tract: A Microarray Study
Q36548179Host restriction factors in retroviral infection: promises in virus-host interaction
Q36738940Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.
Q38732770Human T-cell lymphotropic virus type 1 and its oncogenesis
Q35412479Identification and characterization of HTLV-1 HBZ post-translational modifications
Q35070759Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation
Q36491815Interplay between the HTLV-2 Tax and APH-2 proteins in the regulation of the AP-1 pathway
Q35816954Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL
Q26801294Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence
Q26772930Molecular Studies of HTLV-1 Replication: An Update
Q41724491Molecular and Cellular Mechanism of Leukemogenesis of ATL: Emergent Evidence of a Significant Role for HBZ in HTLV-1-Induced Pathogenesis
Q37939686Molecular mechanisms of HTLV-1 infection and pathogenesis
Q26765424Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis
Q28397941Novel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecycles
Q50056162Regulation of the ATF3 gene by a single promoter in response to amino acid availability and endoplasmic reticulum stress in human primary hepatocytes and hepatoma cells
Q37741026Regulatory role of G9a and LSD1 in the Transcription of Olfactory Receptors during Leukaemia Cell Differentiation
Q38941815Runx2, a target gene for activating transcription factor-3 in human breast cancer cells.
Q39275947SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene
Q36033266Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells
Q43062627The 2011 Retrovirology Prize winner Masao Matsuoka: forward looking and antisense. Interview by Kuan-Teh Jeang
Q42267172The HTLV-1 HBZ protein inhibits cyclin D1 expression through interacting with the cellular transcription factor CREB.
Q52337767The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas
Q26768630The Role of HBZ in HTLV-1-Induced Oncogenesis
Q34494671The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes
Q98721475The splice 1 variant of HTLV-1 bZIP factor stabilizes c-Jun
Q30316429Varying levels of complexity in transcription factor binding motifs
Q36524314WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL?
Q96586662p300 Promotes Cell Proliferation through Suppressing Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Reactivation in the Infected B-Lymphoma Cells

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