Edaravone injection reverses learning and memory deficits in a rat model of vascular dementia

scientific article published on 17 November 2016

Edaravone injection reverses learning and memory deficits in a rat model of vascular dementia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/ABBS/GMW116
P698PubMed publication ID27864280

P2093author name stringWei Li
Xu Li
Xiaohong Li
Yong Yao
Dongmei Zhao
Jiewen Zhang
Fen Lu
Qingkai Yu
Lingzhi Qin
Xinliang Liang
Xuerong Ge
P2860cites workBalance and stability of synaptic structures during synaptic plasticityQ28238403
White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusionQ31119362
Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury.Q33997543
Oxidative stress: oxidants and antioxidantsQ34064540
Vascular cognitive disorder. A biological and clinical overviewQ34153175
CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsQ34166530
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.Q34562025
Edaravone alleviates Alzheimer's disease-type pathologies and cognitive deficitsQ35549137
Molecular abnormalities of the glutamate synapse in the thalamus in schizophreniaQ35610988
Synaptic protein levels altered in vascular dementiaQ35753821
Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function ImpairmentQ35999736
Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseasesQ36734195
Phospholipase A(2), reactive oxygen species, and lipid peroxidation in CNS pathologiesQ37255394
Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990-2010: a systematic review and analysisQ38112886
A modified bilateral carotid artery stenosis procedure to develop a chronic cerebral hypoperfusion rat model with an increased survival rate.Q41479438
Edaravone, a free radical scavenger, protects components of the neurovascular unit against oxidative stress in vitroQ41837296
Vascular dementia in Spatz-Lindenberg's disease (SLD): cortical synaptophysin immunoreactivity as compared with dementia of Alzheimer type and non-demented controlsQ42501828
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicentersQ44418044
Quantitative assessment of cortical synaptic density in Alzheimer's disease.Q44558369
Neurohistological and behavioral changes following the four-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion: comparison between normotensive and spontaneously hypertensive ratsQ45182951
The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia.Q45253597
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brainQ46706351
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementiaQ46987364
Chronic mild reduction of cerebral perfusion pressure induces ischemic tolerance in focal cerebral ischemiaQ48788287
Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities.Q48858670
Acetyl-L-carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C.Q49150263
Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis.Q50730228
Progressive cognitive impairment following chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries in rats.Q52215049
A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.Q53193790
Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias.Q53388305
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectedaravoneQ335099
P304page(s)83-89
P577publication date2016-11-17
P1433published inActa Biochimica et Biophysica SinicaQ2183997
P1476titleEdaravone injection reverses learning and memory deficits in a rat model of vascular dementia
P478volume49

Reverse relations

Q91774684Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Ratscites workP2860

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