Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids.

scientific article published on 16 November 2016

Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.13413
P932PMC publication ID5349920
P698PubMed publication ID27863439

P50authorBruno Lopes-BastosQ88797399
Wen G. JiangQ37842916
P2093author name stringQi Zhou
Chen Wang
Jun Cai
Dong Wang
John Chester
Dongling Zou
Misi He
P2860cites workMolecular mechanisms of curcumin action: signal transductionQ38072888
New strategies in the treatment of ovarian cancer: current clinical perspectives and future potentialQ38073237
Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.Q38303251
Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cellsQ38819183
Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastomaQ38991883
Enrichment of ovarian cancer stem-like cells is associated with epithelial to mesenchymal transition through an miRNA-activated AKT pathwayQ39123447
Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.Q39813179
Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.Q39830064
Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cellsQ43213249
Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cellsQ44239025
Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype.Q46170126
In vitro three-dimensional modelling of human ovarian surface epithelial cells.Q47933101
An international assessment of ovarian cancer incidence and mortality.Q51211236
Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cellsQ56749698
Evolution of platinum resistance in high-grade serous ovarian cancerQ58613175
Eyes wide open: a critical review of sphere-formation as an assay for stem cellsQ24631827
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cellsQ24651034
Treatment options in recurrent ovarian cancer: latest evidence and clinical potentialQ27692699
Cancer statistics, 2013Q27860762
Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolismQ28538384
Tumor metastasis: mechanistic insights and clinical challengesQ29617676
β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsQ30370274
A New Bliss Independence Model to Analyze Drug Combination DataQ30747693
Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995-2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry dataQ33779753
Association between decreases in type V collagen and apoptosis in mouse lung chemical carcinogenesis: a preliminary model to study cancer cell behaviorQ33822890
Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growthQ33892483
Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.Q33980438
Ovarian cancer development and metastasisQ34086819
Curcumin: from ancient medicine to current clinical trials.Q34589151
Curcumin inhibits development and cell adhesion in Dictyostelium discoideum: Implications for YakA signaling and GST enzyme functionQ34673758
Curcumin induces apoptosis in human colorectal carcinoma (HCT-15) cells by regulating expression of Prp4 and p53Q34728269
Spherical cancer models in tumor biologyQ35023931
Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary noteQ35058046
Curcumin Inhibits Non-Small Cell Lung Cancer Cells Metastasis through the Adiponectin/NF-κb/MMPs Signaling PathwayQ35866196
A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancerQ35936614
Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties.Q36025944
Rethinking ovarian cancer: recommendations for improving outcomesQ36050883
Ovarian cancer metastasis: integrating insights from disparate model organismsQ36111930
Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research.Q36358324
Therapeutic roles of curcumin: lessons learned from clinical trialsQ36502400
Understanding and targeting cancer stem cells: therapeutic implications and challengesQ36907405
Novel strategies targeting cancer stem cells through phytochemicals and their analogsQ37198168
Curcumin: the multi-targeted therapy for cancer regressionQ37971755
P433issue52
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
curcuminQ312266
neoplastic stem cellsQ1638475
P304page(s)86374-86387
P577publication date2016-12-01
P1433published inOncotargetQ1573155
P1476titleRe-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids
P478volume7

Reverse relations

cites work (P2860)
Q94538477Ascites-derived ALDH+CD44+ tumour cell subsets endow stemness, metastasis and metabolic switch via PDK4-mediated STAT3/AKT/NF-κB/IL-8 signalling in ovarian cancer
Q92665351Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis
Q49423558Curcumin Inhibits Growth of Human NCI-H292 Lung Squamous Cell Carcinoma Cells by Increasing FOXA2 Expression
Q90191898Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review
Q47630151Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression.
Q57491545Differential Inhibitory Effects of Curcumin Between HPV+ve and HPV-ve Oral Cancer Stem Cells
Q41375618NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin
Q55049874Oxidative stress in female cancers.

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