Eyes wide open: a critical review of sphere-formation as an assay for stem cells

scientific article

Eyes wide open: a critical review of sphere-formation as an assay for stem cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.STEM.2011.04.007
P3181OpenCitations bibliographic resource ID833943
P932PMC publication ID3633588
P698PubMed publication ID21549325
P5875ResearchGate publication ID51104762

P50authorErika PastranaQ41931254
P2093author name stringFiona Doetsch
Violeta Silva-Vargas
P2860cites workNeural stem cells and neurospheres--re-evaluating the relationshipQ48919998
Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cellQ49011276
Continuous live imaging of adult neural stem cell division and lineage progression in vitro.Q50687418
Human corneal endothelial cell precursors isolated by sphere-forming assay.Q51491849
Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells.Q52165452
A specialized vascular niche for adult neural stem cells.Q54237261
Isolation of multipotent adult stem cells from the dermis of mammalian skinQ57042245
Prospectively isolated CD133/CD24-positive ependymal cells from the adult spinal cord and lateral ventricle wall differ in their long-term in vitro self-renewal and in vivo gene expressionQ64026826
bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cellsQ72608792
Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cellsQ72769766
Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelinationQ73265157
Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular zone cellsQ74793148
Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cellsQ81415175
Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arraysQ81724871
CD133 (Prominin) negative human neural stem cells are clonogenic and tripotentQ21562426
Phenotypic and functional characterization of adult brain neuropoiesisQ24529569
The glial nature of embryonic and adult neural stem cellsQ24602498
Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesisQ24647550
Niche-independent symmetrical self-renewal of a mammalian tissue stem cellQ24812526
Spinal cord injury reveals multilineage differentiation of ependymal cellsQ27333067
Subventricular zone astrocytes are neural stem cells in the adult mammalian brainQ28137965
Retinal stem cells in the adult mammalian eyeQ28138858
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cellsQ28218637
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitroQ28219465
Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brainQ28240882
Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulbQ28252251
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biologyQ28264879
Enumeration of neural stem and progenitor cells in the neural colony-forming cell assayQ28265795
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineagesQ28278091
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous systemQ28292445
Critical appraisal of the side population assay in stem cell and cancer stem cell researchQ28304721
Long-distance neuronal migration in the adult mammalian brainQ29616114
Paneth cells constitute the niche for Lgr5 stem cells in intestinal cryptsQ29616197
Generation of a functional mammary gland from a single stem cellQ29616496
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cellsQ29616498
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cellsQ29619410
Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zoneQ30453980
Network of tangential pathways for neuronal migration in adult mammalian brainQ30454288
Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactionsQ30490359
Separating stem cells by flow cytometry: reducing variability for solid tissuesQ30499550
The adult pituitary contains a cell population displaying stem/progenitor cell and early embryonic characteristicsQ33216396
Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.Q33224365
Distinct mammalian precursors are committed to generate neurons with defined dendritic projection patternsQ33305471
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreasQ33591500
Coexistence of quiescent and active adult stem cells in mammalsQ33926891
The road we travelled: discovery, choreography, and significance of brain replaceable neuronsQ34341498
Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heartQ34454071
Identification of a neural stem cell in the adult mammalian central nervous systemQ34492720
Origin of oligodendrocytes in the subventricular zone of the adult brain.Q34551388
Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24.Q34576711
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after strokeQ34949959
Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zoneQ35011868
Isolation and functional characterization of murine prostate stem cellsQ35250689
Regeneration of a germinal layer in the adult mammalian brainQ35659097
Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and gliaQ36150259
CD133+ neural stem cells in the ependyma of mammalian postnatal forebrainQ36458822
Neurosphere assays: growth factors and hormone differences in tumor and nontumor studiesQ36583138
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brainQ37036633
Limiting factors in murine hematopoietic stem cell assays.Q37121020
Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny.Q37159101
Basal cells as stem cells of the mouse trachea and human airway epitheliumQ37271261
Detection and analysis of mammary gland stem cellsQ37325635
Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signalsQ37347634
Cytokine control of adult neural stem cellsQ37399352
High levels of Id1 expression define B1 type adult neural stem cellsQ37417845
Regulation of self-renewal and differentiation in adult stem cell lineages: lessons from the Drosophila male germ lineQ37426157
The role of oxygen in regulating neural stem cells in development and diseaseQ37481081
Multicellular tumor spheroids: an underestimated tool is catching up again.Q37680413
Ultradian Oscillations in Notch Signaling Regulate Dynamic Biological EventsQ37785200
The stem cell potential of glia: lessons from reactive gliosisQ37830315
The cancer stem cell: premises, promises and challengesQ37851011
In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cellsQ39812717
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screensQ39842716
Brain-specific 1B promoter of FGF1 gene facilitates the isolation of neural stem/progenitor cells with self-renewal and multipotent capacitiesQ39929256
Rostro-caudal gradual loss of cellular diversity within the periventricular regions of the ventricular system.Q39989028
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb.Q40187444
Neuronal fate determinants of adult olfactory bulb neurogenesisQ40410529
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cellsQ40570664
Purification of a pluripotent neural stem cell from the adult mouse brainQ40785752
miR-124 regulates adult neurogenesis in the subventricular zone stem cell nicheQ42243673
FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brainQ42462822
Biomimetic platforms for human stem cell researchQ42650130
Computational prediction of neural progenitor cell fates.Q43169800
Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitroQ43420458
The predominant neural stem cell isolated from postnatal and adult forebrain but not early embryonic forebrain expresses GFAP.Q43483505
Astroglia induce neurogenesis from adult neural stem cellsQ43977940
Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres, and undergo multipotent differentiation in vivoQ44280502
The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cellsQ44511956
Intestinal stem cell replacement follows a pattern of neutral driftQ44951523
GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrainQ45115346
Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus.Q46175129
Mosaic organization of neural stem cells in the adult brainQ46817366
Effect of neurosphere size on the growth rate of human neural stem/progenitor cells.Q47317340
Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis.Q48139807
A novel classification of quiescent and transit amplifying adult neural stem cells by surface and metabolic markers permits a defined simultaneous isolationQ48170102
p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cellsQ48171858
A combined ex/in vivo assay to detect effects of exogenously added factors in neural stem cellsQ48181489
Isolation and characterization of murine neural stem/progenitor cells based on Prominin-1 expressionQ48184723
Dorsal radial glia generate olfactory bulb interneurons in the postnatal murine brain.Q48197846
The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells.Q48216999
Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain.Q48230999
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cellsQ48381413
Stem/progenitor cell-specific enhanced green fluorescent protein expression driven by the endogenous Mcm2 promoterQ48410422
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytesQ48413417
LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymalQ48472909
Cell surface N-glycans mediated isolation of mouse neural stem cells.Q48541180
Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortexQ48644064
Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity.Q48692258
The incredible elastic brain: how neural stem cells expand our mindsQ48835638
Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis.Q48857343
Don't look: growing clonal versus nonclonal neural stem cell coloniesQ48874371
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)486-98
P577publication date2011-05-06
P1433published inCell Stem CellQ2943975
P1476titleEyes wide open: a critical review of sphere-formation as an assay for stem cells
P478volume8

Reverse relations

cites work (P2860)
Q987716673D Cell Culture Models Demonstrate a Role for FGF and WNT Signaling in Regulation of Lung Epithelial Cell Fate and Morphogenesis
Q282623423D cultures of human neural progenitor cells: dopaminergic differentiation and genetic modification. [corrected]
Q42007848A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment.
Q91838839A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells
Q46243166A comparative study of the neural stem cell niche in the adult hypothalamus of human, mouse, rat and grey mouse lemur (Microcebus murinus).
Q38016117A detailed mammosphere assay protocol for the quantification of breast stem cell activity.
Q34545236A global transcriptome analysis reveals molecular hallmarks of neural stem cell death, survival, and differentiation in response to partial FGF-2 and EGF deprivation
Q39230008A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells
Q28076963A mosaic world: puzzles revealed by adult neural stem cell heterogeneity
Q58791069A non-canonical role for the proneural gene as a negative regulator of neocortical neurogenesis
Q64298190A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia
Q38716821A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
Q98387346A novel series of substituted 1,2,3-triazoles as cancer stem cell inhibitors: Synthesis and biological evaluation
Q38720963A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics.
Q41623505A reliable method for the sorting and identification of ALDHhigh cancer stem cells by flow cytometry
Q35631496A reliable parameter to standardize the scoring of stem cell spheres
Q28486414A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept
Q28543036A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer
Q90352375ALDH-Dependent Glycolytic Activation Mediates Stemness and Paclitaxel Resistance in Patient-Derived Spheroid Models of Uterine Endometrial Cancer
Q45807888Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma
Q28080068Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening
Q90442508Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype
Q34737502Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures
Q35545627Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression
Q35781395Adipose-derived stem cells promote tumor initiation and accelerate tumor growth by interleukin-6 production
Q64256871Adipose‑derived mesenchymal stem cells exhibit tumor tropism and promote tumorsphere formation of breast cancer cells
Q53823551Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.
Q90139035Adult neurogenesis following ischaemic stroke and implications for cell-based therapeutic approaches
Q34106631Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages
Q38114939Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here
Q41987540Aldehyde dehydrogenase activity enriches for proximal airway basal stem cells and promotes their proliferation.
Q27342050Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations.
Q64258313An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
Q57498202An Updated Review of Oral Cancer Stem Cells and Their Stemness Regulation
Q48687253Analysis of Neural Stem Cells from Human Cortical Brain Structures In Vitro.
Q48111489Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells.
Q35870677Ascl3 marks adult progenitor cells of the mouse salivary gland
Q27301371Assembling neurospheres: dynamics of neural progenitor/stem cell aggregation probed using an optical trap
Q55223907Autophagy and Adult Neurogenesis: Discoveries Made Half a Century Ago Yet in their Infancy of being Connected.
Q57482782BORIS: a key regulator of cancer stemness
Q28066409Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity
Q35354646Biological characteristics of a new human glioma cell line transformed into A2B5(+) stem cells
Q50049701Biomarker discovery for renal cancer stem cells.
Q36957246Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo
Q37244717C-kit(+) cells isolated from developing kidneys are a novel population of stem cells with regenerative potential
Q38683858CANCER STEM CELLS IN OSTEOSARCOMA
Q57452829CD24 regulates cancer stem cell (CSC)-like traits and a panel of CSC-related molecules serves as a non-invasive urinary biomarker for the detection of bladder cancer
Q39040951CD44 and CD24 cannot act as cancer stem cell markers in human lung adenocarcinoma cell line A549.
Q34533871CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.
Q63561064CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells
Q37129032CD49f(high) cells retain sphere-forming and tumor-initiating activities in human gastric tumors
Q37406443CHD7 and retinoic acid signaling cooperate to regulate neural stem cell and inner ear development in mouse models of CHARGE syndrome
Q39158412CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.
Q45048442Cancer Cell Plasticity: Rapid Reversal of Chemosensitivity and Expression of Stemness Markers in Lung and Breast Cancer Tumorspheres
Q38234251Cancer stem cell detection and isolation
Q41777345Cancer stem cell marker phenotypes are reversible and functionally homogeneous in a preclinical model of pancreatic cancer
Q92767250Cancer stem cell self-renewal as a therapeutic target in human oral cancer
Q64066368Cancer stem cell-associated miRNAs serve as prognostic biomarkers in colorectal cancer
Q89743971Cancer stem cell-specific expression profiles reveal emerging bladder cancer biomarkers and identify circRNA_103809 as an important regulator in bladder cancer
Q91840508Cancer stem cells and oral cancer: insights into molecular mechanisms and therapeutic approaches
Q35829972Cancer stem cells in glioblastoma
Q37709551Cancer stem cells in lung cancer: Evidence and controversies.
Q38118769Cancer stem cells in pediatric sarcomas
Q38713728Cancer stem cells in prostate cancer
Q47825118Cancer stem cells: An insight.
Q26771651Cancer stem cells: a metastasizing menace!
Q33569712Cancer stem cells: a systems biology view of their role in prognosis and therapy
Q35586803Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells
Q92340171Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase
Q43114966Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics.
Q42375962Cell density-dependent differential proliferation of neural stem cells on omnidirectional nanopore-arrayed surface
Q39814561Cell division patterns and chromosomal segregation defects in oral cancer stem cells
Q50465582Cells from the adult corneal stroma can be reprogrammed to a neuron-like cell using exogenous growth factors.
Q47920853Cervical cancer stem-like cells: systematic review and identification of reference genes for gene expression
Q28546911Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents
Q94503245Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal
Q41908705Characterization of myelomonocytoid progenitor cells with mesenchymal differentiation potential obtained by outgrowth from pancreas explants
Q38673687Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes.
Q34206687Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor
Q44490396Clonogenic cell subpopulations maintain congenital melanocytic nevi
Q104471839Combined PI3Kα-mTOR Targeting of Glioma Stem Cells
Q35589738Compaction, fusion, and functional activation of three-dimensional human mesenchymal stem cell aggregate
Q92514377Comparison of neural stem/progenitor cells from adult Gecko japonicus and mouse spinal cords
Q39252478Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures
Q33894314DDB2 suppresses tumorigenicity by limiting the cancer stem cell population in ovarian cancer
Q42473230Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin
Q36192058Determining mammosphere-forming potential: application of the limiting dilution analysis
Q38808180Development of a cell line from the American eel brain expressing endothelial cell properties
Q58695296Development of a novel and economical agar-based non-adherent three-dimensional culture method for enrichment of cancer stem-like cells
Q90648273Differential regulation of the sphere formation and maintenance of cancer-initiating cells of malignant mesothelioma via CD44 and ALK4 signaling pathways
Q28533608Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells
Q30557479Dynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1).
Q34421001EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
Q26750598EMT Involved in Migration of Stem/Progenitor Cells for Pituitary Development and Regeneration
Q38652053EMT/MET at the Crossroad of Stemness, Regeneration and Oncogenesis: The Ying-Yang Equilibrium Recapitulated in Cell Spheroids
Q43818984Enabling autologous human liver regeneration with differentiated adipocyte stem cells
Q53474268Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture.
Q33722366EpCAM+ Liver Cancer Stem-Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients
Q34238517Epcam, CD44, and CD49f distinguish sphere-forming human prostate basal cells from a subpopulation with predominant tubule initiation capability
Q90966679Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI
Q52715285Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine.
Q38944343Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
Q50482018Evidence for embryonic stem-like signature and epithelial-mesenchymal transition features in the spheroid cells derived from lung adenocarcinoma.
Q90099858Experimental models and tools to tackle glioblastoma
Q27014292Extracellular matrix and the neural stem cell niche
Q52667943FACS-based Isolation of Neural and Glioma Stem Cell Populations from Fresh Human Tissues Utilizing EGF Ligand.
Q37046814FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway
Q34619436FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells
Q37337795FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.
Q38756540Factors Released from Endothelial Cells Exposed to Flow Impact Adhesion, Proliferation, and Fate Choice in the Adult Neural Stem Cell Lineage
Q89707159Fetal Alcohol Exposure Alters Mammary Epithelial Cell Subpopulations and Promotes Tumorigenesis
Q39098768Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling
Q28385645Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model
Q41959136Functional Characteristics of Multipotent Mesenchymal Stromal Cells from Pituitary Adenomas.
Q36105469G-protein-coupled receptors in adult neurogenesis
Q41571715Gefitinib-loaded DSPE-PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells
Q38094638Generating new neurons to circumvent your fears: the role of IGF signaling.
Q57048305Genetic Abnormalities, Clonal Evolution, and Cancer Stem Cells of Brain Tumors
Q42108815Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions.
Q33579350Genetic profiling of putative breast cancer stem cells from malignant pleural effusions
Q36990814Genetic reconstitution of tumorigenesis in primary intestinal cells
Q39362601Genotype analysis of tumor-initiating cells expressing CD133 in neuroblastoma
Q38225513Glial cells as progenitors and stem cells: new roles in the healthy and diseased brain
Q92500797Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer
Q36898699Glioma stem cells and immunotherapy for the treatment of malignant gliomas
Q37702007Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma
Q31112063Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis
Q102075456HDAC6 promotes growth, migration/invasion, and self-renewal of rhabdomyosarcoma
Q101136375HPV+ve/-ve oral-tongue cancer stem cells: A potential target for relapse-free therapy
Q37936020Head and neck cancer stem cells
Q64234124Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum
Q35823178Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.
Q93120644Heterogeneity of Stem Cells in the Ovary
Q28364998High-Throughput Method for Automated Colony and Cell Counting by Digital Image Analysis Based on Edge Detection
Q50503073High-throughput clonal analysis of neural stem cells in microarrayed artificial niches.
Q38950033How stemlike are sphere cultures from long-term cancer cell lines? Lessons from mouse glioma models
Q33722318Human Lung Spheroids as In Vitro Niches of Lung Progenitor Cells with Distinctive Paracrine and Plasticity Properties.
Q48102996Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease
Q35856865Human Stromal Cells in the Peripheral Zone of the Prostate Promote Tumorigenesis of Prostatic Cancer Stem Cells through Up-regulation of C-Kit Expression
Q36882814Human cardiospheres as a source of multipotent stem and progenitor cells
Q42275873Human foreskin fibroblast-like stromal cells can differentiate into functional hepatocytic cells
Q37619308Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients.
Q47337253Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
Q36916472IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer
Q57169161Identification and differentiation therapy strategy of pterygium in vitro
Q92700673Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells
Q92763940Identification of stemness in primary retinoblastoma cells by analysis of stem-cell phenotypes and tumorigenicity with culture and xenograft models
Q38746734Identification, expansion and characterization of cancer cells with stem cell properties from head and neck squamous cell carcinomas
Q38709641Identifying drug resistant cancer cells using microbubble well arrays
Q36330255Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells.
Q50057434In Vitro Assays of Breast Cancer Stem Cells
Q50430146In Vitro and Ex Ovo Culture of Reptilian and Avian Neural Progenitor Cells
Q34764103In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity.
Q48548827In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity
Q38746669In vitro assays for determining the metastatic potential of melanoma cell lines with characterized in vivo invasiveness
Q28076101In vitro models of cancer stem cells and clinical applications
Q38764733Induced differentiation inhibits sphere formation in neuroblastoma
Q36413827Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2α/androgen receptor signals
Q41017478Inhibition of EGFR induces a c-MET-driven stem cell population in glioblastoma
Q52646506Inhibition of neurosphere formation in neural stem/progenitor cells by acrylamide.
Q39030443Inhibitory activities of trichostatin a in U87 glioblastoma cells and tumorsphere-derived cells.
Q37596299Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion
Q90321120Investigation of multicellular tumor spheroids enriched for a cancer stem cell phenotype
Q35785987Isolated Rat Epididymal Basal Cells Share Common Properties with Adult Stem Cells
Q36335416Isolating single cells in a neurosphere assay using inertial microfluidics
Q36788446Isolation and Culture of Adult Zebrafish Brain-derived Neurospheres
Q52143916Isolation and characterization of neural stem cells from dystrophic mdx mouse.
Q91350131Isolation of Neural Stem Cells from Whole Brain Tissues of Adult Mice
Q38726639Isolation, Characterization, and Establishment of Spontaneously Immortalized Cell Line HRPE-2S With Stem Cell Properties.
Q39055537Isolation, identification, and characterization of cancer stem cells: A review
Q36599973Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population.
Q38609968Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss
Q94550116LGR5+ epithelial tumor stem-like cells generate a 3D-organoid model for ameloblastoma
Q27346608Label-retaining cells in the adult murine salivary glands possess characteristics of adult progenitor cells
Q36245101Large-scale live imaging of adult neural stem cells in their endogenous niche
Q27334201Left atrial appendages from adult hearts contain a reservoir of diverse cardiac progenitor cells
Q26751216Live Imaging of Adult Neural Stem Cells in Rodents
Q45073105LncAPC drives Wnt/β-catenin activation and liver TIC self-renewal through EZH2 mediated APC transcriptional inhibition
Q52356912LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation.
Q55428978LncGPR107 drives the self-renewal of liver tumor initiating cells and liver tumorigenesis through GPR107-dependent manner.
Q60045078LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation
Q54419963LncMAPK6 drives MAPK6 expression and liver TIC self-renewal.
Q37267797MEF promotes stemness in the pathogenesis of gliomas
Q61796855MEK5/ERK5 activation regulates colon cancer stem-like cell properties
Q35460919Mammosphere formation assay from human breast cancer tissues and cell lines.
Q35017138Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin
Q34744495Medullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modifications
Q38942314Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status
Q61449179Metformin selectively targets 4T1 tumorspheres and enhances the antitumor effects of doxorubicin by downregulating the AKT and STAT3 signaling pathways
Q36727107MiRNA Transcriptome Profiling of Spheroid-Enriched Cells with Cancer Stem Cell Properties in Human Breast MCF-7 Cell Line
Q36094121MicroRNA expression profiles of cancer stem cells in head and neck squamous cell carcinoma
Q34354587MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer
Q39021636MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
Q39069525MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β-catenin and ATP-binding cassette, subfamily G, member 2.
Q33631708Minireview: prolactin regulation of adult stem cells
Q91810988Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation
Q94600244Mitochondrial DNA alterations may influence the cisplatin responsiveness of oral squamous cell carcinoma
Q46900782Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
Q33599243Modeling nasopharyngeal carcinoma in three dimensions
Q36842030Modeling pancreatic cancer with organoids
Q36507586Mucin 1-mediated chemo-resistance in lung cancer cells
Q91622156Mutations in SMARCB1 and in other Coffin-Siris syndrome genes lead to various brain midline defects
Q35116675Nardosinone improves the proliferation, migration and selective differentiation of mouse embryonic neural stem cells
Q35569170Nestin depletion induces melanoma matrix metalloproteinases and invasion
Q38110960Neural stem cells as tools for drug discovery: novel platforms and approaches
Q37266566Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery
Q37727816Neural stem cells: are they the hope of a better life for patients with fetal-onset hydrocephalus?
Q24631889Neural stem cells: brain building blocks and beyond
Q34378306Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1alpha expression
Q33861405Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.
Q61804710Non-Invasive Quantification of the Growth of Cancer Cell Colonies by a Portable Optical Coherence Tomography
Q26825948Normal and neoplastic urothelial stem cells: getting to the root of the problem
Q88660924Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B
Q38194550Notching up neural stem cell homogeneity in homeostasis and disease
Q38060099Oncogenic Wnt/β-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research
Q42789167One mouse, two cultures: isolation and culture of adult neural stem cells from the two neurogenic zones of individual mice
Q49270407Opiate Drugs with Abuse Liability Hijack the Endogenous Opioid System to Disrupt Neuronal and Glial Maturation in the Central Nervous System
Q39315396Orosphere assay: a method for propagation of head and neck cancer stem cells
Q38838570Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.
Q37589137Ovarian cancer stem-like cells show induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor
Q50557387PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke.
Q64066083PIP4K2A as a negative regulator of PI3K in PTENdeficient glioblastoma
Q91106528PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation
Q37952082Pancreatic cancer stem cell biology and its therapeutic implications
Q35612391Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells
Q37120436Pbx1 is required for adult subventricular zone neurogenesis
Q38015689Perspectives on cancer stem cells in osteosarcoma
Q28240138Phage display discovery of novel molecular targets in glioblastoma-initiating cells
Q93162823Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma
Q34749993Phenotypic characterization of metastatic anaplastic thyroid cancer stem cells
Q24293124Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells
Q36752069Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts
Q36020891Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity
Q35540959Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Q39223541Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.
Q55519871Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model.
Q98154720Potential role of cancer stem cells as biomarkers and therapeutic targets in cervical cancer
Q57285523Predicting Nanotube Fibrogenicity through Stem Cell-Mediated Fibroblast Focus and Spheroid Formation
Q41883659Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ.
Q34775969Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source
Q35180108Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche
Q33687252Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain
Q38321512Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression.
Q35094509Protein kinase C-δ inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo
Q36480916Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization
Q44112249Purines regulate adult brain subventricular zone cell functions: contribution of reactive astrocytes
Q99594561Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts
Q48001574RNAi screen identifies essential regulators of human brain metastasis-initiating cells.
Q35587475Radiosensitization of Primary Human Glioblastoma Stem-like Cells with Low-Dose AKT Inhibition.
Q38822762Rapamycin inhibited the function of lung CSCs via SOX2.
Q89518810Rational design of small molecule RHOA inhibitors for gastric cancer
Q39174042Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: in vitro model using cancer stem cell enriched ovarian cancer spheroids.
Q52721126Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression.
Q47368468Regulation of RNA polymerase III transcription during transformation of human IMR90 fibroblasts with defined genetic elements.
Q34571352Regulation of progenitor cell proliferation and neuronal differentiation in enteric nervous system neurospheres
Q26772135Regulatory System for Stem/Progenitor Cell Niches in the Adult Rodent Pituitary
Q34138270Ribosomal S6 kinase regulates ischemia-induced progenitor cell proliferation in the adult mouse hippocampus
Q47137381Road to stemness in hepatocellular carcinoma
Q55293322S100A16 up-regulates Oct4 and Nanog expression in cancer stem-like cells of Yumoto human cervical carcinoma cells.
Q47141366SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation
Q34980872SOX2 and OCT4 mRNA-expressing cells, detected by molecular beacons, localize to the center of neurospheres during differentiation
Q41048622SOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells
Q93016744SOX9 expression decreases survival of patients with intrahepatic cholangiocarcinoma by conferring chemoresistance
Q57052668STK899704 inhibits stemness of cancer stem cells and migration via the FAK-MEK-ERK pathway in HT29 cells
Q54961074STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.
Q58120117Salivary gland cell aggregates are derived from self-organization of acinar lineage cells
Q38015339Sarcoma stem cells: do we know what we are looking for?
Q38115251Searching for prostate cancer stem cells: markers and methods
Q98386419Selection of a malignant subpopulation from a colorectal cancer cell line
Q47155023Selective and Irreversible Induction of Necroptotic Cell Death in Lung Tumorspheres by Short-Term Exposure to Verapamil in Combination with Sorafenib.
Q38204950Self-organization of neural tissue architectures from pluripotent stem cells.
Q34714664Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation
Q37287419Side population cells from long-term passage non-small cell lung cancer cells display loss of cancer stem cell-like properties and chemoradioresistance
Q96640475Signaling Inhibitors Accelerate the Conversion of mouse iPS Cells into Cancer Stem Cells in the Tumor Microenvironment
Q38689740Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells
Q28481728Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer
Q34499770Sorting live stem cells based on Sox2 mRNA expression
Q39425169Sphere formation from corneal keratocytes and phenotype specific markers
Q34707863Sphere formation permits Oct4 reprogramming of ciliary body epithelial cells into induced pluripotent stem cells
Q36440751Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells
Q48960317Sphere-forming cells from peripheral cornea demonstrate polarity and directed cell migration.
Q89940616Sphere-forming corneal cells repopulate dystrophic keratoconic stroma: Implications for potential therapy
Q92348105Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target
Q37497377Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma
Q61796403Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells
Q35023931Spherical cancer models in tumor biology
Q36024608Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer
Q39177046Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up.
Q92702089Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS
Q38041726Stem-like cells and therapy resistance in squamous cell carcinomas
Q33832147Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells
Q37061915Strategies for isolating and enriching cancer stem cells: well begun is half done
Q91682606Substituted chloroacetamides as potential cancer stem cell inhibitors: Synthesis and biological evaluation
Q38310095Subventricular zone progenitors in time and space: generating neuronal diversity
Q38438861TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme
Q37730943Targeted Nanotechnology in Glioblastoma Multiforme.
Q48110212Targeting Histone Deacetylase Activity to Arrest Cell Growth and Promote Neural Differentiation in Ewing Sarcoma.
Q92394719Targeting Purinergic Signaling and Cell Therapy in Cardiovascular and Neurodegenerative Diseases
Q49544368Targeting Stemness: Implications for Precision Medicine in Breast Cancer
Q89362026Targeting cancer stem cells with dietary phytochemical - Repositioned drug combinations
Q35894349Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells
Q49425250Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations
Q37290636The Culture-Repopulating Ability assays and incubation in low oxygen: a simple way to test drugs on leukaemia stem or progenitor cells.
Q53281892The Human Embryoid Body Cystic Core Exhibits Architectural Complexity Revealed by use of High Throughput Polymer Microarrays.
Q100381910The Neurosphere Simulator: An educational online tool for modeling neural stem cell behavior and tissue growth
Q53106095The Recent Advances on Liver Cancer Stem Cells: Biomarkers, Separation, and Therapy.
Q26765852The Rise of CRISPR/Cas for Genome Editing in Stem Cells
Q64951606The Role of MicroRNAs in the Regulation of Gastric Cancer Stem Cells: A Meta-Analysis of the Current Status.
Q37993422The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond
Q38899857The chemokine receptor CCR7 promotes mammary tumorigenesis through amplification of stem-like cells
Q35035001The effects of ROCK inhibitor Y-27632 on injectable spheroids of bovine corneal endothelial cells
Q38443193The extracellular matrix compartment of neural stem and glial progenitor cells
Q92287159The feasibility of using dielectrophoresis for isolation of glioblastoma subpopulations with increased stemness
Q48117089The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells.
Q34770376The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale
Q52610051The issue of the multipotency of the neural crest cells.
Q37196447The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche.
Q52431077The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1.
Q33697116The multiple facets of drug resistance: one history, different approaches
Q58794361The neurofilament derived-peptide NFL-TBS.40-63 enters in-vitro in human neural stem cells and increases their differentiation
Q37565410The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer
Q41827406The path from the choroid plexus to the subventricular zone: go with the flow!
Q38125426The role of cancer stem cells in the anti-carcinogenicity of curcumin
Q39031410The role of cancer stem cells in tumor heterogeneity and resistance to therapy
Q38835815The β-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5.
Q93088465Theaflavin-3, 3'-digallate inhibits ovarian cancer stem cells via suppressing Wnt/β-Catenin signaling pathway
Q38942907Therapeutic resistance and cancer recurrence mechanisms: Unfolding the story of tumour coming back
Q35505126Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin
Q26777880Therapies targeting cancer stem cells: Current trends and future challenges
Q38636780Three-Dimensional Models of the Human Brain Development and Diseases
Q34290984Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications.
Q27015644Thyroid tumor-initiating cells: increasing evidence and opportunities for anticancer therapy (review)
Q42286926Towards Organs on Demand: Breakthroughs and Challenges in Models of Organogenesis
Q92761229Towards an advanced cell-based in vitro glioma model system
Q40553571Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells
Q34712867Transcriptional profiling of adult neural stem-like cells from the human brain
Q58719182Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells
Q38476083Translational potential of cancer stem cells: A review of the detection of cancer stem cells and their roles in cancer recurrence and cancer treatment
Q39264794Trending Speculations of Tumor-Initiating Cells in Squamous Cell Cancers of Head and Neck
Q38824383Tumor-Initiating Cells: Emerging Biophysical Methods of Isolation
Q58699122Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
Q37735627Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications
Q41618207Tumor-initiating cells contribute to radiation resistance in primary human renal clear cell carcinomas by activating the DNA damage checkpoint response
Q26777335Tumorsphere as an effective in vitro platform for screening anti-cancer stem cell drugs
Q37666120Tumorsphere assay provides more accurate prediction of in vivo responses to chemotherapeutics
Q26849613Twisted tango: brain tumor neurovascular interactions
Q88561623USP11 Enhances TGFβ-Induced Epithelial-Mesenchymal Plasticity and Human Breast Cancer Metastasis
Q64082557Ultra-multiplexed analysis of single-cell dynamics reveals logic rules in differentiation
Q36438947Ultrastructural evidence of exosome secretion by progenitor cells in adult mouse myocardium and adult human cardiospheres
Q35796886Understanding cancer stem cell heterogeneity and plasticity.
Q53089167Unravelling cancer stem cell potential.
Q41470758Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells
Q41953606Using Primary Neurosphere Cultures to Study Primary Cilia.
Q50670273Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level.
Q53025494VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.
Q26750556White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies
Q38874181Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment.
Q34463427YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissues
Q36090869Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons
Q50766716[Thyroid hormone signalling favors neural stem cell commitment].
Q89611790lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer
Q91745097mEAK-7 Forms an Alternative mTOR Complex with DNA-PKcs in Human Cancer
Q91610564miR-340-5p Suppresses Aggressiveness in Glioblastoma Multiforme by Targeting Bcl-w and Sox2
Q35756885p38α controls self-renewal and fate decision of neurosphere-forming cells in adult hippocampus
Q34589698βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer

Search more.