Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity

scientific article published on 13 February 2013

Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP01254
P932PMC publication ID3570778
P698PubMed publication ID23409245
P5875ResearchGate publication ID235622257

P50authorMichal SchwartzQ21264411
Alon ChenQ54963670
Anat LondonQ120600405
Ayal RonenQ125288774
Ravid ShechterQ125288906
Yael KupermanQ125290227
Asya RollsQ37834540
P2860cites workCrystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptideQ24294695
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in miceQ24523697
Toll-like receptor signallingQ24570126
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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in miceQ27307172
Pattern recognition receptors and inflammationQ27861115
Regulation of lipid metabolism via angiopoietin-like proteinsQ28278721
Central nervous system control of food intakeQ29547439
Crosstalk in NF-κB signaling pathwaysQ29617418
TLR4 links innate immunity and fatty acid-induced insulin resistanceQ29617577
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertionQ29618089
Toll, a muscle cell surface molecule, locally inhibits synaptic initiation of the RP3 motoneuron growth cone in Drosophila.Q52195575
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistanceQ56742768
Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patientsQ74284605
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubesQ79785476
Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesityQ80264331
Neural stem cells: guardians of the brainQ80972857
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammationQ83782039
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistanceQ83864443
Tlr2 is critical for diet-induced metabolic syndrome in a murine model.Q33694600
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout miceQ34097751
Hypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body WeightQ34237623
Toll-like receptor 7 mediates pruritusQ34348756
Regulation of lung injury and repair by Toll-like receptors and hyaluronanQ34462186
Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potentialQ34510368
Overview of toll-like receptors in the CNS.Q34527491
Toll-like receptors modulate adult hippocampal neurogenesisQ34664161
Toll-like receptor 3 is a potent negative regulator of axonal growth in mammalsQ35037100
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficitsQ35963056
Hypothalamic sensing of fatty acidsQ36108719
Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosisQ36119099
The toll-like receptor-nuclear factor kappaB pathway in rheumatoid arthritisQ36170278
Toll-like receptors in central nervous system glial inflammation and homeostasisQ36422953
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesityQ36981204
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferationQ37088433
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesityQ37502701
Toll-like receptors: linking inflammation to metabolismQ37796144
Adipokine gene expression in a novel hypothalamic neuronal cell line: resistin-dependent regulation of fasting-induced adipose factor and SOCS-3.Q40117711
Coordinate regulation of neuropeptide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER) alpha to ERbeta in clonal hypothalamic neuronsQ40283628
Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.Q40589626
Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responsesQ40634487
Elevated expression of the toll like receptors 2 and 4 in obese individuals: its significance for obesity-induced inflammation.Q41907493
Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.Q42058427
Toll-like receptor 4 restricts retinal progenitor cell proliferationQ42124882
Retroviral vectors induce epigenetic chromatin modifications and IL-10 production in transduced B cells via activation of toll-like receptor 2Q42178313
High fat intake induces a population of adipocytes to co-express TLR2 and TNFalpha in mice with insulin resistanceQ42831483
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.Q43091069
Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet.Q43439880
Interleukin-6-deficient mice develop mature-onset obesityQ43851625
Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat.Q45223782
Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's diseaseQ45877904
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.Q46588693
Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene productQ47072878
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
toll-like receptorQ408004
P304page(s)1254
P577publication date2013-02-13
P1433published inScientific ReportsQ2261792
P1476titleHypothalamic neuronal toll-like receptor 2 protects against age-induced obesity
P478volume3

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