| scholarly article | Q13442814 |
| P50 | author | Matteo Villa | Q86630839 |
| Diego Bonetti | Q37373095 | ||
| P2093 | author name string | Elisa Gobbini | |
| Corinne Cassani | |||
| Maria P Longhese | |||
| P2860 | cites work | The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling | Q41916090 |
| Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. | Q41952238 | ||
| Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA. | Q41954516 | ||
| Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks | Q42021074 | ||
| A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres | Q42152601 | ||
| The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle | Q42390204 | ||
| Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks | Q42408271 | ||
| Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions | Q42702038 | ||
| Activation of protein kinase Tel1 through recognition of protein-bound DNA ends | Q42793585 | ||
| The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break | Q43025601 | ||
| TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene | Q48070727 | ||
| Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. | Q53626941 | ||
| The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. | Q53657324 | ||
| FAT: a novel domain in PIK-related kinases | Q57444244 | ||
| Chromosome Fragmentation after Induction of a Double-Strand Break Is an Active Process Prevented by the RMX Repair Complex | Q58486690 | ||
| Tel1p Preferentially Associates with Short Telomeres to Stimulate Their Elongation | Q61314294 | ||
| The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements | Q64387924 | ||
| A DNA damage response pathway controlled by Tel1 and the Mre11 complex | Q64388109 | ||
| The Rad50 hook domain is a critical determinant of Mre11 complex functions | Q64388759 | ||
| TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1 | Q71709839 | ||
| The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities | Q22010967 | ||
| BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair | Q24293244 | ||
| ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex | Q24298863 | ||
| The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair | Q24303369 | ||
| The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks | Q24311761 | ||
| A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage | Q24321669 | ||
| Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95 | Q24323459 | ||
| CDK targets Sae2 to control DNA-end resection and homologous recombination | Q24328867 | ||
| Recombinational repair of gaps in DNA is asymmetric in Ustilago maydis and can be explained by a migrating D-loop model | Q24605056 | ||
| Emerging common themes in regulation of PIKKs and PI3Ks | Q24647293 | ||
| Sources of DNA double-strand breaks and models of recombinational DNA repair | Q27005814 | ||
| Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily | Q27625340 | ||
| Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase | Q27631960 | ||
| The rad50 signature motif: essential to ATP binding and biological function | Q27642866 | ||
| Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair | Q27652502 | ||
| ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. | Q27667335 | ||
| The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair | Q27667404 | ||
| ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex | Q27674381 | ||
| ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling | Q27681577 | ||
| Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
| Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing | Q27929897 | ||
| Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination | Q27930233 | ||
| Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1 | Q27930407 | ||
| A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae | Q27930541 | ||
| Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination | Q27930776 | ||
| Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks | Q27931988 | ||
| A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. | Q27932204 | ||
| The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast | Q27934134 | ||
| Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae | Q27934255 | ||
| Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. | Q27934956 | ||
| Complex formation and functional versatility of Mre11 of budding yeast in recombination | Q27935743 | ||
| Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo | Q27937212 | ||
| The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance | Q27937328 | ||
| Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation | Q27937625 | ||
| DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 | Q27938100 | ||
| Identification of yeast mutants with altered telomere structure | Q27939152 | ||
| DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex | Q27939762 | ||
| The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder | Q28115238 | ||
| Human Rad50/Mre11 is a flexible complex that can tether DNA ends | Q28210390 | ||
| Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA | Q28272303 | ||
| Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks | Q28550291 | ||
| Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks | Q29346869 | ||
| Mechanism of eukaryotic homologous recombination | Q29547709 | ||
| Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
| Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends | Q29615269 | ||
| Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins | Q29615270 | ||
| Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination | Q29615272 | ||
| Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage. | Q33222946 | ||
| Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. | Q33681974 | ||
| DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2 | Q33681983 | ||
| Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast | Q33770453 | ||
| A mechanism of palindromic gene amplification in Saccharomyces cerevisiae | Q33841787 | ||
| ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. | Q33863002 | ||
| End resection at double-strand breaks: mechanism and regulation | Q33938581 | ||
| The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae | Q33960277 | ||
| Expansions and contractions in a tandem repeat induced by double-strand break repair | Q33994800 | ||
| Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes | Q34104835 | ||
| ATM and ataxia telangiectasia | Q34166198 | ||
| Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaks | Q34257112 | ||
| Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex | Q34311086 | ||
| Efficient copying of nonhomologous sequences from ectopic sites via P-element-induced gap repair | Q34336201 | ||
| Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11. | Q34605521 | ||
| The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast | Q34609347 | ||
| Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism | Q34613942 | ||
| Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection | Q34670029 | ||
| Mechanism and regulation of meiotic recombination initiation | Q34931212 | ||
| Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50 | Q34976674 | ||
| The Rad50 coiled-coil domain is indispensable for Mre11 complex functions | Q35300475 | ||
| ATP hydrolysis by RAD50 protein switches MRE11 enzyme from endonuclease to exonuclease | Q35709752 | ||
| Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis | Q35848561 | ||
| Interdependence of the rad50 hook and globular domain functions | Q35922888 | ||
| Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. | Q36154367 | ||
| Requirement of the MRN complex for ATM activation by DNA damage | Q36267304 | ||
| Multiple pathways inhibit NHEJ at telomeres. | Q36585488 | ||
| ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex | Q36759520 | ||
| Rif1 and rif2 inhibit localization of tel1 to DNA ends. | Q37143974 | ||
| mre11S--a yeast mutation that blocks double-strand-break processing and permits nonhomologous synapsis in meiosis | Q37367245 | ||
| Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes | Q37410406 | ||
| The MRE11 complex: starting from the ends. | Q37526483 | ||
| Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length | Q37684164 | ||
| Mechanisms and regulation of DNA end resection | Q37774547 | ||
| The ATM protein kinase: regulating the cellular response to genotoxic stress, and more | Q38088935 | ||
| Repair of double-strand breaks by end joining | Q38103528 | ||
| Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks | Q38129612 | ||
| Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae | Q38308503 | ||
| Mechanisms of ATM Activation | Q38314959 | ||
| Endonucleolytic processing of covalent protein-linked DNA double-strand breaks | Q38322004 | ||
| Mec1 and Tel1: an arresting dance of resection | Q38797453 | ||
| Break dosage, cell cycle stage and DNA replication influence DNA double strand break response | Q38847818 | ||
| A role for the MRN complex in ATR activation via TOPBP1 recruitment | Q39167332 | ||
| A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis | Q39631261 | ||
| Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50. | Q39814819 | ||
| ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism | Q39896119 | ||
| Identification of mammalian proteins cross-linked to DNA by ionizing radiation | Q40386659 | ||
| Microhomology-dependent end joining and repair of transposon-induced DNA hairpins by host factors in Saccharomyces cerevisiae. | Q40468984 | ||
| The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle | Q40619582 | ||
| Ataxia-telangiectasia and cellular responses to DNA damage. | Q40922688 | ||
| The genetic defect in ataxia-telangiectasia | Q41464274 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 329-337 | |
| P577 | publication date | 2016-07-27 | |
| P1433 | published in | Microbial cell (Graz, Austria) | Q56298176 |
| P1476 | title | Functions and regulation of the MRX complex at DNA double-strand breaks | |
| P478 | volume | 3 |
| Q92268657 | DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends |
| Q64387367 | Elimination of Double-Strand Break End Resection Switches Recombination to the Non-homologous End Joining Pathway During Meiosis in Saccharomyces cerevisiae |
| Q93051883 | FgRad50 Regulates Fungal Development, Pathogenicity, Cell Wall Integrity and the DNA Damage Response in Fusarium graminearum |
| Q58696735 | HO Endonuclease-Initiated Recombination in Yeast Meiosis Fails To Promote Homologous Centromere Pairing and Is Not Constrained To Utilize the Dmc1 Recombinase |
| Q52676508 | Ku DNA End-Binding Activity Promotes Repair Fidelity and Influences End-Processing During Nonhomologous End-Joining in Saccharomyces cerevisiae. |
| Q64389072 | Mre11 complex links sister chromatids to promote repair of a collapsed replication fork |
| Q90212650 | PP4 phosphatase cooperates in recombinational DNA repair by enhancing double-strand break end resection |
| Q52723083 | Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment. |
| Q50113705 | Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance. |
| Q60603435 | Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing |
| Q64230105 | The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation |
| Q60932044 | The Emerging Role of Cohesin in the DNA Damage Response |
| Q63965529 | Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability |
| Q52727631 | Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes. |
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