Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani

scientific article published on 13 December 2012

Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00436-012-3212-3
P698PubMed publication ID23239091

P50authorPoonam SalotraQ28869475
Shyam SundarQ58941021
P2093author name stringLouis Maes
Jean Claude Dujardin
Rupkatha Mukhopadhyay
Syamal Roy
V Ramesh
Vasundhra Bhandari
Arpita Kulshrestha
P2860cites workAdvances in leishmaniasisQ29617229
Visceral leishmaniasis control: a public health perspectiveQ34115722
Advances in the treatment of leishmaniasisQ35160721
In vitro susceptibility of field isolates of Leishmania donovani to Miltefosine and amphotericin B: correlation with sodium antimony gluconate susceptibility and implications for treatment in areas of endemicityQ37072017
Relapse of visceral leishmaniasis after miltefosine treatment in a Nepalese patient.Q39335886
In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependentQ39444290
Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine).Q39444314
In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differencesQ41844113
Miltefosine affects lipid metabolism in Leishmania donovani promastigotesQ42067834
Treatment of Visceral Leishmaniasis in 2010: Direction From Bihar State, IndiaQ42879827
Evaluation of hydrogen peroxide-based disinfectants in a new resazurin microplate method for rapid efficacy testing of biocidesQ46080622
A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue.Q50506555
Characterisation of antimony-resistant Leishmania donovani isolates: biochemical and biophysical studies and interaction with host cells.Q51765295
Visceral leishmaniasis, or kala azar (KA): high incidence of refractoriness to antimony is contributed by anthroponotic transmission via post-KA dermal leishmaniasis.Q52669939
Evidence that the High Incidence of Treatment Failures in Indian Kala‐Azar Is Due to the Emergence of Antimony‐Resistant Strains ofLeishmania donovaniQ56781882
Miltefosine as an effective choice in the treatment of post-kala-azar dermal leishmaniasisQ59003574
Post-kala-azar dermal leishmaniasisQ72210953
P433issue2
P921main subjectmiltefosineQ411787
Leishmania donovaniQ1950752
promastigoteQ106395109
P304page(s)825-828
P577publication date2012-12-13
P1433published inParasitology ResearchQ15755242
P1476titleValidation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani
P478volume112

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Q38088424(Post-) Genomic approaches to tackle drug resistance in Leishmania.
Q41874952Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro
Q36237748Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.
Q28550454Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India
Q39014583Evaluating drug resistance in visceral leishmaniasis: the challenges
Q93167639Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani
Q46921246Experimental selection of paromomycin and miltefosine resistance in intracellular amastigotes of Leishmania donovani and L. infantum
Q37225817In vitro susceptibility of Leishmania donovani to miltefosine in Indian visceral leishmaniasis
Q33797614Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress
Q28285948Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance
Q39063747Lack of correlation between the promastigote back-transformation assay and miltefosine treatment outcome
Q39462738Leishmanicidal Activity and Structure-Activity Relationships of Essential Oil Constituents
Q57293286Lipase precursor like protein promotes miltefosine tolerance in by enhancing parasite infectivity and eliciting anti-inflammatory responses in host macrophages
Q91975125Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches
Q24611966Relapse after treatment with miltefosine for visceral leishmaniasis is associated with increased infectivity of the infecting Leishmania donovani strain
Q59801068Second-generation pterocarpanquinones: synthesis and antileishmanial activity
Q39020376Susceptibility Testing of Medically Important Parasites
Q88574829Susceptibility of promastigotes and intracellular amastigotes from distinct Leishmania species to the calpain inhibitor MDL28170

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