Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres

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Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres is …
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scholarly articleQ13442814

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P819ADS bibcode2012NatCo...3.1074C
P6179Dimensions Publication ID1017277456
P356DOI10.1038/NCOMMS2091
P8608Fatcat IDrelease_zmnnsedpcncbno6a2w4q6acniy
P698PubMed publication ID23011128

P2093author name stringLi Wu
Yong Chen
Jinsong Ren
Konggang Qu
Xiaogang Qu
Jiasi Wang
Chuanqi Zhao
P2860cites workInduction of aneuploidy by single-walled carbon nanotubesQ23916633
Highly prevalent putative quadruplex sequence motifs in human DNAQ24529050
Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNAQ24814949
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolutionQ27644404
TRF2 Protects Human Telomeres from End-to-End FusionsQ28111898
DNA damage foci at dysfunctional telomeresQ29614811
Regulation of telomerase by telomeric proteinsQ29616133
Inhibition of telomerase by G-quartet DNA structuresQ30450395
How telomeres solve the end-protection problemQ30959036
Structure-based carbon nanotube sorting by sequence-dependent DNA assemblyQ31029680
Functional human telomeres are recognized as DNA damage in G2 of the cell cycleQ33227804
Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.Q33260827
Knocking-down cyclin A(2) by siRNA suppresses apoptosis and switches differentiation pathways in K562 cells upon administration with doxorubicinQ33494037
A human nuclease specific for G4 DNAQ33947771
Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory rolesQ34002192
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhangQ34082359
Making sense of G‐quadruplex and i‐motif functions in oncogene promotersQ34271763
Extension of G-quadruplex DNA by ciliate telomeraseQ34468325
Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells.Q34546519
Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor geneQ34609291
Carbon nanotubes selective destabilization of duplex and triplex DNA and inducing B-A transition in solution.Q34977487
G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicaseQ35153446
The structure of telomeric DNA.Q35165218
Carboxyl-modified single-walled carbon nanotubes selectively induce human telomeric i-motif formationQ35544451
Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplexQ35562505
Indecent exposure: when telomeres become uncappedQ35632849
T-loops and the origin of telomeresQ35741027
Inhibition of human telomerase by 2'-O-methyl-RNAQ36312946
Stability and kinetics of G-quadruplex structuresQ36909305
Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA.Q36909314
The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expressionQ37375112
Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligandsQ37385440
DNA loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivityQ39775145
G-tail telomere HPA: simple measurement of human single-stranded telomeric overhangsQ40352922
Cytosine-block telomeric type DNA-binding activity of hnRNP proteins from human cell lines.Q40680488
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activityQ40737219
G-quadruplex nucleic acids as therapeutic targetsQ41786267
Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities.Q42126674
Optical detection of DNA conformational polymorphism on single-walled carbon nanotubesQ42805817
Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.Q44030336
Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathwaysQ44549002
Biological activity of the G-quadruplex ligand RHPS4 (3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) is associated with telomere capping alterationQ45013871
Self-assembly of single-stranded RNA on carbon nanotube: polyadenylic acid to form a duplex structureQ45877150
Processive utilization of the human telomerase template: lack of a requirement for template switchingQ46109951
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cellsQ46815329
Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhangQ47240761
Telomeric 3'-overhang length is associated with the size of telomeresQ47246659
Hydration regulates thermodynamics of G-quadruplex formation under molecular crowding conditions.Q51181744
Single-walled carbon nanotubes binding to human telomeric i-motif DNA under molecular-crowding conditions: more water molecules released.Q53477531
Single-walled carbon nanotubes binding to human telomeric i-motif DNA: significant acceleration of S1 nuclease cleavage rate.Q53512551
Direct imaging of single-walled carbon nanotubes in cells.Q54152431
siRNA Delivery into Human T Cells and Primary Cells with Carbon-Nanotube TransportersQ56785863
Reversible Accumulation of PEGylated Single-Walled Carbon Nanotubes in the Mammalian NucleusQ57166285
i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon NanotubesQ60698352
The i-motif in nucleic acidsQ73889028
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cellsQ78109179
Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell typeQ81697625
Label-free colorimetric detection of single nucleotide polymorphism by using single-walled carbon nanotube intrinsic peroxidase-like activityQ83075158
A DNA nanomachine induced by single-walled carbon nanotubes on gold surfaceQ83148802
P407language of work or nameEnglishQ1860
P921main subjectcarbon nanotubeQ1778729
single-walled carbon nanotubeQ115764330
P304page(s)1074
P577publication date2012-01-01
P1433published inNature CommunicationsQ573880
P1476titleInsights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres
P478volume3

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