| scholarly article | Q13442814 |
| P2093 | author name string | Laurence H Hurley | |
| Tracy A Brooks | |||
| Vijay Gokhale | |||
| Forest L Danford | |||
| Robert V Brown | |||
| P2860 | cites work | Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription | Q24535577 |
| Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression | Q24652408 | ||
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| Transcription of human c-myc in permeabilized nuclei is associated with formation of Z-DNA in three discrete regions of the gene | Q30792215 | ||
| c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations | Q31929763 | ||
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| A competition dialysis assay for the study of structure-selective ligand binding to nucleic acids | Q81131564 | ||
| Cellular nucleic-acid-binding protein, a transcriptional enhancer of c-Myc, promotes the formation of parallel G-quadruplexes | Q84068043 | ||
| Fluorescence-based melting assays for studying quadruplex ligands | Q33283370 | ||
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| Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression | Q33843587 | ||
| Making decisions through Myc. | Q34164607 | ||
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| The C-Terminus of Nucleolin Promotes the Formation of the c-MYC G-Quadruplex and Inhibits c-MYC Promoter Activity | Q34293129 | ||
| Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance | Q34314752 | ||
| Targeting MYC Expression through G-Quadruplexes | Q34352558 | ||
| Contributions of Myc to tumorigenesis | Q34605526 | ||
| Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene | Q34609291 | ||
| Modelling Myc inhibition as a cancer therapy | Q34811008 | ||
| Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. | Q35204486 | ||
| Supercoil-driven DNA structures regulate genetic transactions | Q36814027 | ||
| Cloning and sequencing of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region | Q36886353 | ||
| Stability and kinetics of G-quadruplex structures | Q36909305 | ||
| The c-myc promoter: still MysterY and challenge | Q37013896 | ||
| Oncogene addiction | Q37152445 | ||
| The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression | Q37375112 | ||
| Transcription is associated with Z-DNA formation in metabolically active permeabilized mammalian cell nuclei | Q37433277 | ||
| Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma | Q37606881 | ||
| The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics | Q37631442 | ||
| The c-MYC NHE III(1): function and regulation | Q37634542 | ||
| Activation of the c-myc oncogene by the immunoglobulin heavy-chain gene enhancer after multiple switch region-mediated chromosome rearrangements in a murine plasmacytoma | Q37690084 | ||
| Enigmatic MYC Conducts an Unfolding Systems Biology Symphony. | Q37827073 | ||
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| Novel molecular mechanism for actinomycin D activity as an oncogenic promoter G-quadruplex binder | Q38353496 | ||
| Small-molecule-mediated G-quadruplex isolation from human cells | Q39627688 | ||
| Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression | Q39800990 | ||
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| Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways. | Q40386886 | ||
| c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability. | Q40615463 | ||
| Skp2 regulates Myc protein stability and activity | Q40644685 | ||
| Identification of processes that influence negative supercoiling in the human c-myc gene | Q41108875 | ||
| In K562 leukemia cells treated with doxorubicin and hemin, a decrease in c-myc mRNA expression correlates with loss of self-renewal capability but not with erythroid differentiation | Q41292941 | ||
| Targeted melting and binding of a DNA regulatory element by a transactivator of c-myc | Q41351007 | ||
| Selective recognition of a DNA G-quadruplex by an engineered antibody | Q42559983 | ||
| Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1. | Q42819058 | ||
| Regulation of c-myc expression by PDGF through Rho GTPases. | Q42828450 | ||
| Expression of cellular oncogenes in human malignancies | Q43491818 | ||
| Identification of c-myc as a down-stream target for pituitary tumor-transforming gene | Q46290466 | ||
| P433 | issue | 47 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 41018-41027 | |
| P577 | publication date | 2011-09-28 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex | |
| P478 | volume | 286 |
| Q36092148 | Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c-MYC promoter |
| Q54204671 | Benzothiazole hydrazones of furylbenzamides preferentially stabilize c-MYC and c-KIT1 promoter G-quadruplex DNAs. |
| Q34194286 | Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines |
| Q57471938 | Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex |
| Q57472261 | Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene |
| Q37051064 | DNA secondary structures: stability and function of G-quadruplex structures |
| Q44585292 | DNA structure: Visualizing the quadruplex |
| Q38703728 | Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative |
| Q50191357 | Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex |
| Q47561729 | Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status |
| Q89880050 | From R-Loops to G-Quadruplexes: Emerging New Threats for the Replication Fork |
| Q92835757 | G-Quadruplex DNA and RNA |
| Q38151013 | G-quadruplex structures in the human genome as novel therapeutic targets. |
| Q37994254 | G-quadruplexes: targets and tools in anticancer drug design |
| Q34323620 | Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay |
| Q26744714 | Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles |
| Q41630512 | Identification of G-Quadruplex Inducers Usinga Simple, Inexpensiveand Rapid High Throughput Assay, and TheirInhibition of Human Telomerase |
| Q90333802 | In Silico Screening and Binding Characterization of Small Molecules toward a G-Quadruplex Structure Formed in the Promoter Region of c-MYC Oncogene |
| Q38302099 | In silico identification of novel ligands for G-quadruplex in the c-MYC promoter |
| Q92283167 | In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells |
| Q39271563 | Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres |
| Q57295564 | Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA |
| Q29619979 | MYC on the path to cancer |
| Q59072385 | Mammalian MYC Proteins and Cancer |
| Q92490663 | Mission Possible: Advances in MYC Therapeutic Targeting in Cancer |
| Q34377302 | Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia |
| Q35797583 | Molecular classification, pathway addiction, and therapeutic targeting in diffuse large B cell lymphoma |
| Q90477297 | New substituted quinoxalines inhibit triple-negative breast cancer by specifically downregulating the c-MYC transcription |
| Q41509732 | Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4 |
| Q64893017 | Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry. |
| Q37507524 | Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex |
| Q38084251 | Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization. |
| Q36620686 | Old drug, new target: ellipticines selectively inhibit RNA polymerase I transcription |
| Q58696695 | Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding |
| Q90859674 | Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics |
| Q64267793 | Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy |
| Q99614289 | Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases |
| Q35805318 | Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression |
| Q41677833 | Small molecule selectively suppresses MYC transcription in cancer cells |
| Q52593929 | Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint. |
| Q47384193 | Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X. |
| Q92773892 | Splice-switching small molecules: A new therapeutic approach to modulate gene expression |
| Q36303678 | Strategies to Inhibit Myc and Their Clinical Applicability |
| Q27681217 | Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter |
| Q41077413 | Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor |
| Q36762189 | Targeting MYC in cancer therapy: RNA processing offers new opportunities |
| Q38194418 | Targeting RNA polymerase I to treat MYC-driven cancer. |
| Q48195145 | Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule. |
| Q38119470 | Targeting non-B-form DNA in living cells |
| Q51038636 | Targeting promoter G-quadruplex DNAs by indenopyrimidine-based ligands. |
| Q38704867 | The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Target |
| Q34374607 | The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1. |
| Q33558251 | U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence |
| Q42351696 | c-Myc and cancer metabolism |
| Q58772561 | i-Motif DNA: structural features and significance to cell biology |
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