Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization

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Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.01102-06
P932PMC publication ID1642171
P698PubMed publication ID16956933

P50authorJoseph SodroskiQ64524473
P2093author name stringSimon Cocklin
Irwin Chaiken
Inna Lipchina
Xinzhen Yang
P2860cites workThe HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensQ22242262
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infectionQ24538985
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1Q28646812
Antibody neutralization and escape by HIV-1Q29547345
Rapid evolution of the neutralizing antibody response to HIV type 1 infectionQ29618603
Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.Q33737656
Neutralization profiles of primary human immunodeficiency virus type 1 isolates in the context of coreceptor usageQ33783714
Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1.Q33786382
Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivoQ33821658
Species-specific, postentry barriers to primate immunodeficiency virus infectionQ33824990
Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeysQ33839485
Antibody and virus: binding and neutralizationQ33895369
Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virusQ34364045
Multiple interactions across the surface of the gp120 core structure determine the global neutralization resistance phenotype of human immunodeficiency virus type 1Q35105006
HIV sequence databasesQ35182711
Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.Q35841780
HIV-1: the confounding variables of virus neutralizationQ36173037
Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation.Q36366296
Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementationQ36685254
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomesQ36796806
Stoichiometry of monoclonal antibody neutralization of T-cell line-adapted human immunodeficiency virus type 1Q39595900
Antibody binding and neutralization of primary and T-cell line-adapted isolates of human immunodeficiency virus type 1.Q39610187
Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodiesQ39698363
Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same siteQ39699375
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.Q39868309
Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complexQ39878965
Modulation of Env content in virions of simian immunodeficiency virus: correlation with cell surface expression and virion infectivityQ40546009
Passage of HIV-1 molecular clones into different cell lines confers differential sensitivity to neutralizationQ41076585
The ratio of defective HIV-1 particles to replication-competent infectious virionsQ41492441
Neutralizing Antibody Response During Human Immunodeficiency Virus Type 1 Infection: Type and Group Specificity and Viral EscapeQ41558189
Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virusQ41611077
Dissociation of gp120 from HIV-1 virions induced by soluble CD4.Q41714439
An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteinsQ42086489
Morphometric analysis of envelope glycoprotein gp120 distribution on HIV-1 virionsQ44285196
Neutralization escape in human immunodeficiency virus type 1-infected long-term nonprogressorsQ45750292
Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virusQ45848179
Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera.Q45849314
Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virusQ45859822
Distinct biological and serological properties of human immunodeficiency viruses from the brain.Q46038323
Native HIV type 1 virion surface structures: relationships between antibody binding and neutralization or lessons from the viral capture assayQ47444177
Retrieval and on-the-fly alignment of sequence fragments from the HIV databaseQ48679004
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.Q55487007
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P1104number of pages5
P304page(s)11404-11408
P577publication date2006-09-06
P1433published inJournal of VirologyQ1251128
P1476titleAntibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization
P478volume80

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cites work (P2860)
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