Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system

scientific article

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/GTC.12434
P698PubMed publication ID27717094

P50authorYoshihiro YonedaQ87114508
P2093author name stringMasahiro Oka
Kazuaki Yoshikawa
Koichi Hasegawa
Kazushiro Fujiwara
P2860cites workRanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolismQ21145250
Association of the human SUMO-1 protease SENP2 with the nuclear poreQ24292472
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.Q24305181
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complexQ24310068
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2Q24317523
NTF2 mediates nuclear import of Ran.Q24533395
Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2Q24548973
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1Q24600785
Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2Q27676384
Detecting endogenous SUMO targets in mammalian cells and tissuesQ27865266
In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodiesQ28115445
The Ki-67 protein: from the known and the unknownQ28143714
CDC6: from DNA replication to cell cycle checkpoints and oncogenesisQ28259261
Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiationQ28505942
Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3Q28509725
Regulation of neuron survival and death by p130 and associated chromatin modifiersQ28567953
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complexQ29617624
Nuclear import of Ran is mediated by the transport factor NTF2.Q30473025
Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligaseQ33727985
Cell cycle regulators in neural stem cells and postmitotic neuronsQ33913344
Multiple mechanisms regulate subcellular localization of human CDC6.Q33946248
Nucleocytoplasmic protein traffic and its significance to cell functionQ34058859
Necdin controls proliferation of white adipocyte progenitor cellsQ34146581
SUMO2 is essential while SUMO3 is dispensable for mouse embryonic developmentQ34338850
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysisQ34449803
p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortexQ34666832
The Ran GTPase: theme and variationsQ34784733
Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphomaQ35040346
Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortexQ35083411
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viabilityQ35178128
The Ran GTPase-activating protein (RanGAP1) is critically involved in smooth muscle cell differentiation, proliferation and migration following vascular injury: implications for neointima formation and restenosisQ35200173
The E3 ligase APC/C-Cdh1 regulates MEF2A-dependent transcription by targeting SUMO-specific protease 2 for ubiquitination and degradationQ36182197
Cellular stresses induce the nuclear accumulation of importin alpha and cause a conventional nuclear import blockQ36322431
From radial glia to pyramidal-projection neuron: transcription factor cascades in cerebral cortex developmentQ36358077
The direction of transport through the nuclear pore can be invertedQ36428044
The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear importQ36631203
Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insultsQ36690552
Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoterQ36790661
Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1.Q37158107
Spatial and temporal coordination of mitosis by Ran GTPaseQ37163028
Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryoQ37178230
Neocortical neurogenesis: morphogenetic gradients and beyondQ37301122
SUMOylation and De-SUMOylation: wrestling with life's processesQ37325310
Shuttling of SOX proteinsQ37609628
Necdin acts as a transcriptional repressor that interacts with multiple guanosine clustersQ38298538
Downregulation of the small GTPase ras-related nuclear protein accelerates cellular ageingQ39243279
Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.Q39612422
Neural stem cell‐like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirusQ39632461
Triggering neural differentiation of ES cells by subtype switching of importin-alphaQ40198151
A murine homolog of the yeast RNA1 gene is required for postimplantation development.Q44651022
Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neuronsQ46407035
Mechanism of the stress-induced collapse of the Ran distributionQ46861497
Necdin downregulates CDC2 expression to attenuate neuronal apoptosis.Q48368860
Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.Q50892653
Necdin controls EGFR signaling linked to astrocyte differentiation in primary cortical progenitor cells.Q53248620
Senescence-related functional nuclear barrier by down-regulation of nucleo-cytoplasmic trafficking gene expression.Q53490953
Control of the Cdc6 replication licensing factor in metazoa: the role of nuclear export and the CUL4 ubiquitin ligase.Q53499769
P433issue11
P304page(s)1176-1194
P577publication date2016-09-22
P1433published inGenes to CellsQ1524078
P1476titleTerminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system
P478volume21

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Q64896079RanGAP-mediated nucleocytoplasmic transport of Prospero regulates neural stem cell lifespan in Drosophila larval central brain.cites workP2860

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