Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase

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Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...999503G
P356DOI10.1371/JOURNAL.PONE.0099503
P932PMC publication ID4049815
P698PubMed publication ID24911587
P5875ResearchGate publication ID262940210

P2093author name stringKazuaki Yoshikawa
Koichi Hasegawa
Kazushiro Fujiwara
Ibrahim Gur
P2860cites workIdentification of a new, unorthodox member of the MAGE gene familyQ28139872
Physical and functional interactions of neuronal growth suppressor necdin with p53Q28144785
Cellular and subcellular localization of necdin in fetal and adult mouse brainQ28144941
The ‘PINIT’ motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3LQ28181614
Expression of necdin, an embryonal carcinoma-derived nuclear protein, in developing mouse brainQ28189907
Induction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activationQ28206174
An overview of the MAGE gene family with the identification of all human members of the familyQ28206480
Necdin interacts with the ribonucleoprotein hnRNP U in the nuclear matrixQ28216773
Ectopic expression of necdin induces differentiation of mouse neuroblastoma cellsQ28219184
PIAS proteins: pleiotropic interactors associated with SUMOQ28248545
The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouseQ28249408
The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal regionQ28253418
Concepts in sumoylation: a decade onQ28257220
Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1Q28258359
Regulation of gene-activation pathways by PIAS proteins in the immune systemQ28264801
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?Q28280175
Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cellsQ28505040
Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survivalQ28508839
Disruption of the mouse necdin gene results in early post-natal lethalityQ28587922
Differential evolution of MAGE genes based on expression pattern and selection pressureQ28714314
A SIM-ultaneous role for SUMO and ubiquitinQ33327630
A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cellsQ33652807
Development of a self-inactivating lentivirus vector.Q33784841
Evolutionary history of the cancer immunity antigen MAGE gene family.Q33939709
Necdin protects embryonic motoneurons from programmed cell deathQ34017758
SP-RING for SUMO: new functions bloom for a ubiquitin-like proteinQ34094595
Necdin controls proliferation of white adipocyte progenitor cellsQ34146581
Necdin enhances myoblasts survival by facilitating the degradation of the mediator of apoptosis CCAR1/CARP1Q34385015
The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic diseaseQ34561533
Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortexQ35083411
Core filaments of the nuclear matrixQ36222649
The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated fociQ36619481
Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoterQ36790661
Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.Q37594860
SUMO and ubiquitin paths converge.Q37674654
The Smc5/6 complex: more than repair?Q37861962
Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins.Q38303507
PIAS1-modulated Smad2/4 complex activation is involved in zinc-induced cancer cell apoptosisQ39093908
Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.Q39362556
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathwayQ39992451
MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell linesQ40066322
A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activationQ40126919
Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppressionQ40485094
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damageQ40729232
The tumor suppressor Pml regulates cell fate in the developing neocortexQ42447614
Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neuronsQ46407035
Drosophila MAGE controls neural precursor proliferation in postembryonic neurogenesisQ47070317
Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotypeQ47841909
Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.Q47930961
A MAGE/NDN-like gene in zebrafishQ48162186
Necdin downregulates CDC2 expression to attenuate neuronal apoptosis.Q48368860
Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome.Q49155367
Necdin controls proliferation and apoptosis of embryonic neural stem cells in an oxygen tension-dependent manner.Q50892653
The imprinted gene Magel2 regulates normal circadian output.Q51976832
Necdin is required for terminal differentiation and survival of primary dorsal root ganglion neuronsQ74361128
Expression of Drosophila MAGE gene encoding a necdin homologous protein in postembryonic neurogenesisQ79329412
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID FamiliesQ24294572
Necdin-related MAGE Proteins Differentially Interact with the E2F1 Transcription Factor and the p75 Neurotrophin ReceptorQ24298935
MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin LigasesQ24300816
Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complexQ24304051
The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARAQ24307375
Inhibition of Stat1-mediated gene activation by PIAS1Q24310082
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human MelanomaQ24319940
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradationQ24320385
Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complexQ24322634
The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion regionQ24336557
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodiesQ24599898
A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologuesQ24797302
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organizationQ27930326
The nucleoporin RanBP2 has SUMO1 E3 ligase activityQ28115025
The polycomb protein Pc2 is a SUMO E3Q28115324
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e99503
P577publication date2014-06-09
P1433published inPLOS OneQ564954
P1476titleNecdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase
P478volume9

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cites work (P2860)
Q47137780B Cell Receptor Activation and Chemical Induction Trigger Caspase-Mediated Cleavage of PIAS1 to Facilitate Epstein-Barr Virus Reactivation.
Q47105992Characterization of MAGEG2 with testis-specific expression in mice
Q36369146Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer.
Q59127320PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation
Q38246971Regulation of the metastasis suppressor Nm23-H1 by tumor viruses
Q39311609Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system
Q38581531The MAGE protein family and cancer.

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