Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival

scientific journal article

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.2083-05.2005
P8608Fatcat IDrelease_bznfregnpre2vhastqpanc6pja
P932PMC publication ID6724840
P698PubMed publication ID16049186

P2093author name stringMasato Okada
Shigeyuki Nada
Kazuaki Yoshikawa
Masashi Yamada
Isao Nishimura
Ken-ichiro Kuwako
Taichi Uetsuki
Akari Hosokawa
P2860cites workNecdin-related MAGE Proteins Differentially Interact with the E2F1 Transcription Factor and the p75 Neurotrophin ReceptorQ24298935
Sortilin is essential for proNGF-induced neuronal cell deathQ24312692
The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion regionQ24336557
Regulation of cell survival by secreted proneurotrophinsQ27919620
Trk receptors: roles in neuronal signal transductionQ27919636
NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosisQ28138611
Physical and functional interactions of neuronal growth suppressor necdin with p53Q28144785
Cellular and subcellular localization of necdin in fetal and adult mouse brainQ28144941
Requirement of nerve growth factor for development of substance P-containing sensory neuronesQ72621102
Neuronally-expressed necdin gene: an imprinted candidate gene in Prader-Willi syndromeQ73920284
Necdin is required for terminal differentiation and survival of primary dorsal root ganglion neuronsQ74361128
Expression of necdin, an embryonal carcinoma-derived nuclear protein, in developing mouse brainQ28189907
The p75 neurotrophin receptor interacts with multiple MAGE proteinsQ28213040
Ectopic expression of necdin induces differentiation of mouse neuroblastoma cellsQ28219184
The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouseQ28249408
The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal regionQ28253418
Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1Q28258359
Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cellsQ28505040
Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal miceQ28505055
Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowthQ28508700
Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiationQ28513619
Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin bindingQ28564163
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neuronsQ28584797
Disruption of the mouse necdin gene results in early post-natal lethalityQ28587922
NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expressionQ28591595
Neurotrophins and their receptors: a convergence point for many signalling pathwaysQ29616108
E2F: a link between the Rb tumor suppressor protein and viral oncoproteinsQ29618375
A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cellsQ33652807
Cell cycle regulators in neural stem cells and postmitotic neuronsQ33913344
Prader-Willi syndrome: consensus diagnostic criteria.Q34061685
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous systemQ34103744
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.Q34338664
Constitutive activation of Src family kinases in mouse embryos that lack Csk.Q34366689
BDNF regulates eating behavior and locomotor activity in miceQ34667950
Neurotrophin signaling through the p75 neurotrophin receptorQ34778209
The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous systemQ34982367
Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root gangliaQ35200638
Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalitiesQ36784651
Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoterQ36790661
Cell death during development of the nervous systemQ37716922
Arrest of Cell Growth by Necdin, a Nuclear-Protein Expressed in Postmitotic NeuronsQ42825285
Impaired peripheral somatosensory function in children with Prader-Willi syndromeQ47304792
Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursorQ48432892
Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer.Q48493406
Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome.Q49155367
Expression of the Prader-Willi gene Necdin during mouse nervous system development correlates with neuronal differentiation and p75NTR expression.Q52097061
Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia.Q52223036
Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein.Q53229787
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectNeurotrophic tyrosine kinase, receptor, type 1Q14901156
Necdin, MAGE family memberQ21984208
Tumor necrosis factor receptor superfamily member 16Q21988151
P304page(s)7090-7099
P577publication date2005-07-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleDisruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival
P478volume25

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cites work (P2860)
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Q98163300Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader-Willi syndrome
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Q41791587Functional consequences of necdin nucleocytoplasmic localization.
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Q48109362Loss of Necdin impairs myosin activation and delays cell polarization
Q51953730Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons.
Q34086646Lower brain-derived neurotrophic factor in patients with prader-willi syndrome compared to obese and lean control subjects
Q38152232Mechanism of pain generation for endometriosis-associated pelvic pain
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Q37456880Necdin and TrkA contribute to modulation by p75NTR of resistance to oxidant stress.
Q34911741Necdin and neurotrophin receptors: interactors of relevance for neuronal resistance to oxidant stress
Q39362556Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis.
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Q34146581Necdin controls proliferation of white adipocyte progenitor cells
Q48368860Necdin downregulates CDC2 expression to attenuate neuronal apoptosis.
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Q36690552Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults
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Q31138426Stochastic loss of silencing of the imprinted Ndn/NDN allele, in a mouse model and humans with prader-willi syndrome, has functional consequences
Q54292334Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury.
Q24321957The Prader-Willi syndrome protein necdin interacts with the E1A-like inhibitor of differentiation EID-1 and promotes myoblast differentiation
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