Calpain and MARCKS protein regulation of airway mucin secretion

scientific article

Calpain and MARCKS protein regulation of airway mucin secretion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PUPT.2012.06.003
P932PMC publication ID3486950
P698PubMed publication ID22710197
P5875ResearchGate publication ID227341884

P2093author name stringKenneth B Adler
Shijing Fang
Joungjoa Park
Anne L Crews
W Randall Lampe
P2860cites workMARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitroQ28215052
MARCKS is a natively unfolded protein with an inaccessible actin-binding site: evidence for long-range intramolecular interactionsQ28910181
MARCKS-related peptide modulates in vivo the secretion of airway Muc5acQ34180777
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanismQ35221784
Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS proteinQ36202835
Regulation of airway mucin gene expressionQ36216587
Respiratory tract mucin genes and mucin glycoproteins in health and diseaseQ36350071
Phospholipase C is a key enzyme regulating intracellular calcium and modulating the phosphoinositide balanceQ37765689
Myoblast migration is prevented by a calpain-dependent accumulation of MARCKS.Q38346034
MARCKS and related chaperones bind to unconventional myosin V isoforms in airway epithelial cellsQ39732214
TRPC1 regulates skeletal myoblast migration and differentiationQ39918781
Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma proteinQ40180712
Myristoylated alanine-rich C kinase substrate (MARCKS) is involved in myoblast fusion through its regulation by protein kinase Calpha and calpain proteolytic cleavageQ40538423
Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization.Q40599716
Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factorsQ40624164
Myristoylated alanine-rich C-kinase substrate (MARCKS) protein regulation of human neutrophil migration.Q40684672
Myristoylation-dependent N-terminal cleavage of the myristoylated alanine-rich C kinase substrate (MARCKS) by cellular extractsQ40851260
Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotypeQ41553917
Phagocytic and macropinocytic activity in MARCKS-deficient macrophages and fibroblastsQ42474836
Mesenchymal stem cells require MARCKS protein for directed chemotaxis in vitroQ42872109
Actin filament cross-linking by MARCKS: characterization of two actin-binding sites within the phosphorylation site domain.Q43569558
An ELISA method for the quantitation of tracheal mucins from human and nonhuman primatesQ46129529
Biologically active milli-calpain associated with caveolae is involved in a spatially compartmentalised signalling involving protein kinase C alpha and myristoylated alanine-rich C-kinase substrate (MARCKS).Q46516310
A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthmaQ48033163
Development-associated myristoylated alanine-rich C kinase substrate phosphorylation in rat brainQ48361111
Specific proteolytic cleavage of the myristoylated alanine-rich C kinase substrate between Asn 147 and Glu 148 also occurs in brainQ48717301
Inhibition of mucin secretion with MARCKS-related peptide improves airway obstruction in a mouse model of asthmaQ62803258
P433issue6
P304page(s)427-431
P577publication date2012-06-16
P1433published inPulmonary Pharmacology & TherapeuticsQ7259517
P1476titleCalpain and MARCKS protein regulation of airway mucin secretion
P478volume25

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cites work (P2860)
Q28385209Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol
Q38704976ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins
Q40961367Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment.
Q34805664Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein.
Q38734458MARCKS is involved in methylmercury-induced decrease in cell viability and nitric oxide production in EA.hy926 cells
Q52336325MARCKS phosphorylation by PKC strongly impairs cell polarity in the chick neural plate.
Q90218690Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b
Q46280869Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD.
Q38217069Targeting mucus hypersecretion: new therapeutic opportunities for COPD?
Q47147564The MARCKS protein amount is differently regulated by calpain during toxic effects of methylmercury between SH-SY5Y and EA.hy926 cells.
Q40505147The nasal methylome and childhood atopic asthma

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