MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.

scientific article published on 31 May 2017

MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/14728222.2017.1336227
P932PMC publication ID6130320
P698PubMed publication ID28562118

P50authorLin LengQ85637007
Pathricia V TilstamQ59663420
P2093author name stringRichard Bucala
Dake Qi
Lawrence Young
P2860cites workMacrophage migration inhibitory factor promoter polymorphisms and the clinical expression of sclerodermaQ79318135
Macrophage migration inhibitory factor: a probable link between inflammation and cancerQ80003629
Macrophage migration inhibitory factor (MIF) and oligoarticular juvenile idiopathic arthritis (o-JIA): association of MIF promoter polymorphisms with response to intra-articular glucocorticoidsQ80195889
Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaquesQ81202695
A single nucleotide polymorphism of macrophage migration inhibitory factor is related to inflammatory response in coronary bypass surgery using cardiopulmonary bypassQ82778825
Deletion of macrophage migration inhibitory factor protects the heart from severe ischemia-reperfusion injury: a predominant role of anti-inflammationQ83152715
Cardioprotection through S-nitros(yl)ation of macrophage migration inhibitory factorQ83638984
Macrophage migration inhibitory factor antagonizes pressure overload-induced cardiac hypertrophyQ85412079
Increased expression of macrophage migration inhibitory factor in aorta of patients with coronary atherosclerosisQ95515974
MIF signal transduction initiated by binding to CD74Q24303802
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complexQ24307384
Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studiesQ24816150
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasionQ27481089
Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolutionQ27617542
Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallographyQ27629426
The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agentsQ27638947
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilastQ27662149
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitmentQ27684665
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1Q28138425
Macrophage migration inhibitory factor: a regulator of innate immunityQ28204158
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health dataQ28242645
Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindoleQ28257604
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemiaQ28265011
The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunityQ28295198
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitmentQ28298072
Increased CD74 expression in human atherosclerotic plaques: contribution to inflammatory responses in vascular cellsQ47858881
Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductaseQ47885573
Phase I, multicentre, dose-escalation trial of monotherapy with milatuzumab (humanized anti-CD74 monoclonal antibody) in relapsed or refractory multiple myelomaQ50765392
Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activityQ51092500
Progress in interventional cardiology: challenges for the futureQ51152036
Targeted intracellular accumulation of macrophage migration inhibitory factor in the reperfused heart mediates cardioprotection.Q53371260
Serum macrophage migration inhibitory factor levels are associated with angiographically complex coronary lesions in patients with coronary artery diseaseQ53383286
Association of macrophage migration inhibitory factor -173C allele polymorphism with steroid resistance in children with nephrotic syndrome.Q53845656
Up-regulation and coexpression of MIF and matrix metalloproteinases in human abdominal aortic aneurysms.Q54647435
Macrophage migration inhibitory factor increases leukocyte-endothelial interactions in human endothelial cells via promotion of expression of adhesion molecules.Q54667217
Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: Results from the MONICA/KORA Augsburg case-cohort study, 1984–2002Q57303220
A polymorphism in the macrophage migration inhibitory factor gene is involved in the genetic predisposition of Crohn's disease and associated with cumulative steroid dosesQ60689149
Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF)Q63915224
Stabilization of Atherosclerotic Plaques by Blockade of Macrophage Migration Inhibitory Factor After Vascular Injury in Apolipoprotein E–Deficient MiceQ63915243
Protection from septic shock by neutralization of macrophage migration inhibitory factorQ64132865
Macrophage Migration Inhibitory Factor Provides Cardioprotection During Ischemia/Reperfusion by Reducing Oxidative StressQ64374815
Expression of Macrophage Migration Inhibitory Factor in Acute Ischemic Myocardial InjuryQ73293115
Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritisQ73316815
Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IkappaBalphaQ74217866
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritisQ74315912
Elevation of plasma level of macrophage migration inhibitory factor in patients with acute myocardial infarctionQ74598901
Expression of macrophage migration inhibitory factor in different stages of human atherosclerosisQ77857409
Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74.Q46669179
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activityQ46669596
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.Q46781819
Evidence for a role of macrophage migration inhibitory factor in vascular diseaseQ47232432
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complexQ28588442
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune responseQ28592426
Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid actionQ28594433
Macrophage Migration Inhibitory Factor Is Enhanced in Acute Coronary Syndromes and Is Associated with the Inflammatory ResponseQ28728841
Progress and challenges in translating the biology of atherosclerosisQ29619982
The changing face of cardiovascular disease 2000-2012: An analysis of the world health organisation global health estimates dataQ30244192
Chronic coronary artery disease: diagnosis and managementQ30492121
A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1Q30830656
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of actionQ33591955
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolitesQ33896841
Association between the -794 (CATT)5-8  MIF gene polymorphism and susceptibility to acute coronary syndrome in a western Mexican population.Q33930320
The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injuryQ33944140
Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heartQ34009213
Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF)Q34127116
The Action of D-Dopachrome Tautomerase as an Adipokine in Adipocyte Lipid MetabolismQ34200909
Receptor agonists of macrophage migration inhibitory factorQ34340164
RTL therapy for multiple sclerosis: a Phase I clinical study.Q34520672
Myocardial reperfusion injury.Q34687124
Macrophage migration inhibitory factor in cardiovascular diseaseQ34764306
Differential roles of cardiac and leukocyte derived macrophage migration inhibitory factor in inflammatory responses and cardiac remodelling post myocardial infarctionQ35049835
A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.Q35071632
The D -dopachrome tautomerase ( DDT ) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)Q35180790
Macrophage migration inhibitory factor polymorphism is associated with susceptibility to inflammatory coronary heart diseaseQ35189344
Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factorQ35391070
Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosusQ35585133
The macrophage migration inhibitory factor protein superfamily in obesity and wound repairQ35681520
Regulation of macrophage migration inhibitory factor expression by glucocorticoids in vivoQ35748894
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progressionQ35760817
An Analysis of MIF Structural Features that Control Functional Activation of CD74.Q36075317
Interaction of MIF Family Proteins in Myocardial Ischemia/Reperfusion Damage and Their Influence on Clinical Outcome of Cardiac Surgery PatientsQ36191684
New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosusQ36245929
Macrophage migration inhibitory factor: gene polymorphisms and susceptibility to inflammatory diseasesQ36291764
Myocardial ischemia-reperfusion injury: a neglected therapeutic targetQ36497176
Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus.Q36515036
Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy RegulationQ36650905
Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasiaQ36797421
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitmentQ36935739
Relationship between elevated soluble CD74 and severity of experimental and clinical ALI/ARDSQ37117393
Chemokine-like functions of MIF in atherosclerosisQ37127327
Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screeningQ37187080
Limiting Cardiac Ischemic Injury by Pharmacological Augmentation of Macrophage Migration Inhibitory Factor–AMP-Activated Protein Kinase Signal TransductionQ37193766
Pro-inflammatory action of MIF in acute myocardial infarction via activation of peripheral blood mononuclear cellsQ37209979
Plasma Macrophage Migration Inhibitor Factor Is Elevated in Response to Myocardial IschemiaQ37240620
The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumoniaQ37280809
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic diseaseQ37280881
Exogenous Administration of Recombinant MIF at Physiological Concentrations Failed to Attenuate Infarct Size in a Langendorff Perfused Isolated Mouse Heart ModelQ37321912
Inflammation and plaque vulnerabilityQ37370224
The role of macrophage migration inhibitory factor in autoimmune liver diseaseQ37423459
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.Q37493256
D-dopachrome tautomerase in adipose tissue inflammation and wound repairQ37539870
Predicted structure of MIF/CD74 and RTL1000/CD74 complexesQ37595880
Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early LifeQ37604131
MIF Gene Polymorphism rs755622 Is Associated With Coronary Artery Disease and Severity of Coronary Lesions in a Chinese Kazakh Population: A Case-Control StudyQ37624131
D-dopachrome tautomerase (D-DT or MIF-2): Doubling the MIF cytokine familyQ38002982
Macrophage migration inhibitory factor in myocardial ischaemia/reperfusion injuryQ38199944
Role of MIF in myocardial ischaemia and infarction: insight from recent clinical and experimental findingsQ38201763
Systemic inflammatory response following acute myocardial infarctionQ38531965
AMPK: energy sensor and survival mechanism in the ischemic heartQ38544724
Platelet-derived MIF: a novel platelet chemokine with distinct recruitment properties.Q38922918
d-Dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytesQ39285040
The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burnQ39746527
Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusionQ39773528
The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor.Q39849398
Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activityQ40169158
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1.Q40362124
Impact of counterbalance between macrophage migration inhibitory factor and its inhibitor Gremlin-1 in patients with coronary artery diseaseQ41739542
Molecular Pathways Underlying Cardiac Remodeling During Pathophysiological StimulationQ41855920
Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagyQ41967343
Macrophage migration inhibitory factor exhibits a pronounced circadian rhythm relevant to its role as a glucocorticoid counter-regulatorQ42438155
Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.Q42661328
Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusionQ43159405
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulationQ43163083
Macrophage migration inhibitory factor as a redox-sensitive cytokine in cardiac myocytesQ43818599
The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosisQ44355422
Association between MIF gene polymorphisms and carotid artery atherosclerosisQ44492214
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsisQ46663769
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectcardiovascular diseaseQ389735
P304page(s)671-683
P577publication date2017-07-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inExpert Opinion on Therapeutic TargetsQ5421214
P1476titleMIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics
P478volume21

Reverse relations

cites work (P2860)
Q64122506Correlation between Plasma Macrophage Migration Inhibitory Factor Levels and Long-Term Prognosis in Patients with Acute Myocardial Infarction Complicated with Diabetes
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Q100526128Genetic regulation of gene expression of MIF family members in lung tissue
Q51734324Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.
Q64245639Macrophage Migration Inhibitory Factor (MIF) Expression Increases during Myocardial Infarction and Supports Pro-Inflammatory Signaling in Cardiac Fibroblasts
Q91026071Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling
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Q92637631The Role of Macrophage Migration Inhibitory Factor in Alzheimer's Disease: Conventionally Pathogenetic or Unconventionally Protective?

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