Survivin inhibition by an interacting recombinant peptide, derived from the human ferritin heavy chain, impedes tumor cell growth

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Survivin inhibition by an interacting recombinant peptide, derived from the human ferritin heavy chain, impedes tumor cell growth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00432-012-1195-1
P698PubMed publication ID22426960
P5875ResearchGate publication ID221715383

P2093author name stringBernd Groner
Boris Brill
Natalia Delis
Corina Borghouts
Laura Mack
Astrid Weiss
P2860cites workSurvivin mediates targeting of the chromosomal passenger complex to the centromere and midbodyQ24338808
Direct inhibition of the NOTCH transcription factor complexQ24634015
Ferritin for the clinicianQ24642942
The mitotic regulator Survivin binds as a monomer to its functional interactor BorealinQ27648318
Current prospects for RNA interference-based therapiesQ28235733
Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeuticsQ28290655
Cancer gene therapy using a survivin mutant adenovirusQ28360690
Genome remodelling in a basal-like breast cancer metastasis and xenograftQ28395637
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vectorQ29547503
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivoQ29616612
Principles of cancer therapy: oncogene and non-oncogene addictionQ29616779
Balancing acts: molecular control of mammalian iron metabolismQ29620380
Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid proceduresQ33280955
Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry.Q33314548
Identification of a small-molecule inhibitor of the interaction between Survivin and Smac/DIABLO.Q33527675
Binding and uptake of H-ferritin are mediated by human transferrin receptor-1.Q33734849
Induction of apoptosis by survivin silencing through siRNA delivery in a human breast cancer cell lineQ33991776
Ferritin H induction by histone deacetylase inhibitorsQ34034477
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4FQ34508797
Drugs, their targets and the nature and number of drug targetsQ34571023
Cell signaling in space and time: where proteins come together and when they're apartQ34583620
The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family membersQ34727955
Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivinQ34871780
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemiaQ35182716
Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell deathQ35183027
Our changing view of the genomic landscape of cancerQ35368205
Survivin and IAP proteins in cell-death mechanismsQ35414780
Cellular regulation and molecular interactions of the ferritins.Q36390445
Survivin, a cancer target with an emerging role in normal adult tissuesQ36491426
X-linked inhibitor of apoptosis protein as a therapeutic targetQ37008849
Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunctionQ37149240
Cancer cells survive with survivinQ37185505
IAP-targeted therapies for cancerQ37302745
New wirings in the survivin networksQ37302750
Reversing cancer from inside and out: oncogene addiction, cellular senescence, and the angiogenic switchQ37354200
Survivin: a new target for anti-cancer therapyQ37533048
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.Q37574259
Dynamic interactions of proteins in complex networks: a more structured view.Q37588014
Exploiting the balance between life and death: targeted cancer therapy and "oncogenic shock".Q37704646
Promises and challenges in developing RNAi as a research tool and therapyQ37815111
Is survivin the potential Achilles' heel of cancer?Q37894400
Bio-inspired, bioengineered and biomimetic drug delivery carriersQ37896455
The intracellular delivery of a recombinant peptide derived from the acidic domain of PIAS3 inhibits STAT3 transactivation and induces tumor cell deathQ39718244
Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibitionQ40006737
Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cellsQ40016776
Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chainQ40216949
Induction of melanoma cell apoptosis and inhibition of tumor growth using a cell-permeable Survivin antagonistQ40279512
The druggable genome: an updateQ40362716
High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoterQ45732758
Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycinQ46656725
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivoQ48548442
Early embryonic lethality of H ferritin gene deletion in mice.Q52171353
Monitoring the interference of protein-protein interactions in vivo by bimolecular fluorescence complementation: the DnaK case.Q52693279
High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastomaQ63874527
Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesisQ64377539
N-Terminal Deletion Effects of Human Survivin on Dimerization and Binding to Smac/DIABLO in VitroQ82377205
P433issue7
P921main subjectcell growthQ189159
P304page(s)1205-1220
P577publication date2012-03-18
P1433published inJournal of Cancer Research and Clinical OncologyQ2081599
P1476titleSurvivin inhibition by an interacting recombinant peptide, derived from the human ferritin heavy chain, impedes tumor cell growth
P478volume138

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cites work (P2860)
Q34657717Association of survivin splice variants with prognosis and treatment of breast cancer
Q38239577Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration
Q42227148Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms.
Q33275528Examination of survivin expression in 50 chordoma specimens--A histological and in vitro study
Q38395896Hypoxic tumor microenvironment in advanced retinoblastoma.
Q38028795Increasing the range of drug targets: interacting peptides provide leads for the development of oncoprotein inhibitors
Q38212609Oncoapoptotic markers in oral cancer: prognostics and therapeutic perspective
Q49392235Survivin regulated by autophagy mediates hyperglycemia-induced vascular endothelial cell dysfunction
Q38040407Targeting malignant mitochondria with therapeutic peptides.
Q27022941Targeting oncogenic ALK and MET: a promising therapeutic strategy for glioblastoma
Q34954296Targeting survivin in cancer: novel drug development approaches

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