Expression and clinical relevance of MET and ALK in Ewing sarcomas.

scientific article

Expression and clinical relevance of MET and ALK in Ewing sarcomas. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/IJC.28047
P698PubMed publication ID23335077

P50authorEmmy FleurenQ57231770
William LeendersQ60537446
Yvonne M H Versleijen-JonkersQ83069386
P2093author name stringOtto C Boerman
Winette T A van der Graaf
Myrella Vlenterie
Melissa H S Roeffen
Uta E Flucke
Hendrik W Schreuder
P2860cites workAnaplastic lymphoma kinase inhibition in non-small-cell lung cancerQ27851588
c-Met: structure, functions and potential for therapeutic inhibitionQ28190143
Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell linesQ28214508
Targeting the c-Met signaling pathway in cancerQ28246393
Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous systemQ28304840
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinomaQ30494514
Angiogenesis and vascular targeting in Ewing sarcoma: a review of preclinical and clinical dataQ33520467
Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptorQ34172489
The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcomaQ34414730
An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanismsQ34625881
Initial testing (stage 1) of the IGF-1 receptor inhibitor BMS-754807 by the pediatric preclinical testing program.Q34683782
Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinomaQ35108386
VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancerQ35112894
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinibQ35666332
Anaplastic lymphoma kinase proteins in growth control and cancerQ35750450
Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology GroupQ36389207
Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancerQ36822111
The anaplastic lymphoma kinase in the pathogenesis of cancerQ37039605
Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the futureQ37182432
Inhibition of ALK signaling for cancer therapyQ37593792
Targets for cancer therapy in childhood sarcomasQ37707632
Anaplastic lymphoma kinase aberrations in rhabdomyosarcoma: clinical and prognostic implications.Q39673956
Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patientsQ39805159
ALK (Anaplastic Lymphoma Kinase) expression in DRG neurons and its involvement in neuron-Schwann cells interaction.Q39886471
Initial testing (stage 1) of sunitinib by the pediatric preclinical testing programQ40009993
Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing programQ40015224
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing programQ40141410
MET overexpression turns human primary osteoblasts into osteosarcomas.Q40285015
Prognostic significance of c-Met expression in glioblastomasQ46170165
Expression of anaplastic lymphoma kinase in soft tissue tumors: an immunohistochemical and molecular study of 249 casesQ47369102
Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1.Q48029331
Expression of c-Met correlates with grade of malignancy in human astrocytic tumours: an immunohistochemical studyQ48571377
Coexpression of HGF and c-Met/HGF receptor in human bone and soft tissue tumors.Q54158447
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcabozantinibQ795057
P304page(s)427-436
P577publication date2013-02-25
P1433published inInternational Journal of CancerQ332492
P1476titleExpression and clinical relevance of MET and ALK in Ewing sarcomas
P478volume133

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cites work (P2860)
Q50587004A preliminary study on a new model system to evaluate tumour-detection and tumour-purging protocols in ovarian cortex tissue intended for fertility preservation.
Q27310990ALK kinase domain mutations in primary anaplastic large cell lymphoma: consequences on NPM-ALK activity and sensitivity to tyrosine kinase inhibitors
Q34414378ALK-driven tumors and targeted therapy: focus on crizotinib
Q39780992Aminopyridyl/Pyrazinyl Spiro[indoline-3,4'-piperidine]-2-ones As Highly Selective and Efficacious c-Met/ALK Inhibitors
Q89803105Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial
Q89803112Cabozantinib: a new perspective for advanced bone sarcoma
Q91948077EWSR1/FUS-NFATc2 rearranged round cell sarcoma: clinicopathological series of 4 cases and literature review
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Q64114432Management of recurrent Ewing sarcoma: challenges and approaches
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Q47333317Pediatric Development of Molecularly Targeted Oncology Drugs
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Q52795602miR-152 down-regulation is associated with MET up-regulation in leiomyosarcoma and undifferentiated pleomorphic sarcoma.

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