PKCδ-induced PU.1 phosphorylation promotes hematopoietic stem cell differentiation to dendritic cells

scientific article published on February 2011

PKCδ-induced PU.1 phosphorylation promotes hematopoietic stem cell differentiation to dendritic cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/STEM.564
P698PubMed publication ID21732487
P5875ResearchGate publication ID51470499

P2093author name stringAndré Berger
Egbert Flory
Matthias Hamdorf
Jens Reinhardt
Silke Schüle
P2860cites workNegative cross-talk between hematopoietic regulators: GATA proteins repress PU.1Q24671782
Physical and functional interactions between the transcription factor PU.1 and the coactivator CBPQ28137946
CRD-BP/IMP1 expression characterizes cord blood CD34+ stem cells and affects c-myc and IGF-II expression in MCF-7 cancer cellsQ28239956
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaQ28251443
Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fateQ28298291
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitorsQ28594083
Activation and repression of interleukin-12 p40 transcription by erythroid Kruppel-like factor in macrophagesQ34246568
Ex vivo expansion of hematopoietic stem cells by cytokinesQ34991834
Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cellsQ35121751
Differential recruitment of PKC isoforms in HeLa cells during redox stressQ36259332
Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complexQ36351968
Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiationQ36402468
The protein kinase C (PKC) family of proteins in cytokine signaling in hematopoiesisQ36929019
MAPK signaling pathways in the regulation of hematopoiesisQ37508518
Differential roles of PI3-Kinase, MAPKs and NF-kappaB on the manipulation of dendritic cell T(h)1/T(h)2 cytokine/chemokine polarizing profileQ39839173
Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genesQ40099900
Cytokine-induced myeloid differentiation is dependent on activation of the MEK/ERK pathwayQ40373169
PKCdelta and zeta mediate IL-4/IL-13-induced germline epsilon transcription in human B cells: a putative regulation via PU.1 phosphorylationQ40775721
Induction of erythroid differentiation by inhibition of Ras/ERK pathway in a friend murine leukemia cell lineQ40891246
Signal transduction pathways induced by GM-CSF in microglia: significance in the control of proliferationQ40945904
The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytesQ41135284
Role of PU.1 in hematopoiesisQ41706344
Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cellsQ41965708
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.Q42194328
Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signalingQ43058016
IL-2 induction by simian immunodeficiency virus involves MAP kinase signaling but is independent of calcineurin/NF-AT activityQ43455133
Ontogeny-associated changes in the cytokine responses of primitive human haemopoietic cellsQ47801551
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.Q52214235
Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells.Q52537914
Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.Q53654630
P433issue2
P921main subjectcell differentiationQ210861
phosphorylationQ242736
stem cell differentiationQ14864672
dendritic cellQ506253
P304page(s)297-306
P577publication date2011-02-01
P1433published inStem CellsQ15724411
P1476titlePKCδ-induced PU.1 phosphorylation promotes hematopoietic stem cell differentiation to dendritic cells
P478volume29

Reverse relations

cites work (P2860)
Q30524109A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes
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Q37044058Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche
Q40671991Analyses of basal media and serum for in vitro expansion of suspension peripheral blood mononucleated stem cell
Q36648624Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.
Q37246466Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer.
Q49571851HER2 overexpression triggers an IL-1α pro-inflammatory circuit to drive tumorigenesis and promote chemotherapy resistance
Q37527686Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies
Q24300286IL-32θ negatively regulates IL-1β production through its interaction with PKCδ and the inhibition of PU.1 phosphorylation
Q49320015IL-32θ: a recently identified anti-inflammatory variant of IL-32 and its preventive role in various disorders and tumor suppressor activity
Q90147177Inhibitory mechanism of ginsenoside Rh3 on granulocyte-macrophage colony-stimulating factor expression in UV-B-irradiated murine SP-1 keratinocytes
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Q36083704Macrophage dectin-1 expression is controlled by leukotriene B4 via a GM-CSF/PU.1 axis
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