Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.

scientific article published on 12 May 2011

Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/ME.2010-0517
P932PMC publication ID5417251
P698PubMed publication ID21566083

P50authorJohn ChallisQ105069900
P2093author name stringMartin Gleave
Ning Xie
Stephen J Lye
Xuesen Dong
Liangliang Liu
Paul Rennie
P2860cites workThe snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factorQ22008524
PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptorsQ24290950
Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactionsQ24291592
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosisQ24298775
hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structuresQ24312215
Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6Q24313187
Cloning and characterization of PSF, a novel pre-mRNA splicing factorQ24322621
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factorQ24338249
Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasionQ24522742
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1Q24530659
Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTDQ24540125
A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionQ24594778
The pathobiology of splicingQ24634680
Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-2 3'-UTRQ24670536
The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription terminationQ24671920
Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response elementQ28137944
PSF/p54(nrb) stimulates "jumping" of DNA topoisomerase I between separate DNA helicesQ28138562
An RNA recognition motif (RRM) is required for the localization of PTB-associated splicing factor (PSF) to subnuclear specklesQ28143133
Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcriptionQ28207701
PSF and p54(nrb)/NonO--multi-functional nuclear proteinsQ28213410
The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrbQ28278347
The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interactionQ28284025
Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1Q28295145
Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbetaQ28305986
Alternative pre-mRNA splicing and proteome expansion in metazoansQ29618540
Transcriptional activity of androgen receptor is modulated by two RNA splicing factors, PSF and p54nrb.Q30444291
NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphomaQ30831857
Identification of tyrosine-phosphorylated proteins associated with the nuclear envelopeQ31896700
p54nrb is a transcriptional corepressor of the progesterone receptor that modulates transcription of the labor-associated gene, connexin 43 (Gja1).Q33642227
Splicing potentiation by growth factor signals via estrogen receptor phosphorylationQ33852237
Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivoQ33925205
ParaspecklesQ33931966
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes.Q34310192
p54nrb is a component of the snRNP-free U1A (SF-A) complex that promotes pre-mRNA cleavage during polyadenylationQ34366770
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Coupling transcription, splicing and mRNA exportQ35145838
Phosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tractQ35741673
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathwayQ36299920
Interaction of protein phosphatase type 1 with a splicing factor.Q36814895
Functional integration of transcriptional and RNA processing machineriesQ37147522
Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing.Q38297672
PTB-associated splicing factor regulates growth factor-stimulated gene expression in mammalian cellsQ38363210
NH2 terminus of PTB-associated splicing factor binds to the porcine P450scc IGF-I response elementQ39611175
Combinatorial control of signal-induced exon repression by hnRNP L and PSF.Q40100408
CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicingQ40376847
Identification and characterization of the protein-associated splicing factor as a negative co-regulator of the progesterone receptor.Q40466349
Intramolecular interactions between the AF3 domain and the C-terminus of the human progesterone receptor are mediated through two LXXLL motifsQ40550430
Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activityQ43961222
Identification of PSF as a protein kinase Calpha-binding protein in the cell nucleusQ44060004
Coordinate regulation of transcription and splicing by steroid receptor coregulatorsQ44177314
Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription.Q52544550
A Mammalian Activity Required for the Second Step of Pre-messenger RNA SplicingQ58673175
Myotonic dystrophy: the role of the CUG triplet repeats in splicing of a novel DMPK exon and altered cytoplasmic DMPK mRNA isoform ratiosQ74057903
Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factorsQ77702159
The splicing factor PSF is part of a large complex that assembles in the absence of pre-mRNA and contains all five snRNPsQ79370507
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partnersQ83968708
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)1197-1210
P577publication date2011-05-12
P1433published inMolecular EndocrinologyQ3319475
P1476titleConsensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.
P478volume25

Reverse relations

cites work (P2860)
Q35955993C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1.
Q33590301Modulation the alternative splicing of GLA (IVS4+919G>A) in Fabry disease
Q90304553NONO and tumorigenesis: More than splicing
Q35758656New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription
Q35772782PSF: nuclear busy-body or nuclear facilitator?
Q37661658Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells
Q93176831RNF8 mediates NONO degradation following UV-induced DNA damage to properly terminate ATR-CHK1 checkpoint signaling
Q36637610Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia
Q34522376The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold
Q52865368The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.
Q36197666The adipogenic transcriptional cofactor ZNF638 interacts with splicing regulators and influences alternative splicing
Q37649097The transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression
Q38757337Tyrosine Residues Regulate Multiple Nuclear Functions of P54nrb.

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