Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: effect of nutrient supplementation

scientific article published on 7 May 2011

Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: effect of nutrient supplementation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/BIT.23165
P698PubMed publication ID21495016
P5875ResearchGate publication ID51053059

P50authorGyun Min LeeQ88339254
P2093author name stringSo Jeong Lee
Jae Seong Lee
Young Kue Han
Tae Kwang Ha
P2860cites workInhibition of macroautophagy triggers apoptosisQ24338482
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Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cellsQ39833907
Effect of Bcl-xL overexpression on apoptosis and autophagy in recombinant Chinese hamster ovary cells under nutrient-deprived conditionQ39876149
Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cellsQ40209217
Down-regulation of lactate dehydrogenase-A by siRNAs for reduced lactic acid formation of Chinese hamster ovary cells producing thrombopoietinQ40211655
RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cellsQ40252560
Metabolism of PER.C6 cells cultivated under fed-batch conditions at low glucose and glutamine levelsQ40307631
Nuclear caspase-3 and caspase-7 activation, and poly(ADP-ribose) polymerase cleavage are early events in camptothecin-induced apoptosisQ40336726
Impact of dynamic online fed-batch strategies on metabolism, productivity and N-glycosylation quality in CHO cell cultures.Q40461540
Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.Q40896291
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In hybridoma cultures, deprivation of any single amino acid leads to apoptotic death, which is suppressed by the expression of the bcl-2 geneQ40963466
The importance of ammonia in mammalian cell cultureQ41009633
Effects of ammonia on CHO cell growth, erythropoietin production, and glycosylationQ41921972
Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidaseQ42486241
Analysis of CHO cells metabolic redistribution in a glutamate-based defined medium in continuous culture.Q43817062
Role of vitamins in determining apoptosis and extent of suppression by bcl-2 during hybridoma cell cultureQ43984651
Effect of culture pH on erythropoietin production by Chinese hamster ovary cells grown in suspension at 32.5 and 37.0 degrees C.Q45206706
Rapamycin pre-treatment protects against apoptosisQ45300160
Life and death partners: apoptosis, autophagy and the cross-talk between themQ46072576
Effect of Akt overexpression on programmed cell death in antibody-producing Chinese hamster ovary cellsQ47254100
Acute hydrodynamic forces and apoptosis: a complex question.Q51006184
Optimization of fed-batch parameters and harvest time of CHO cell cultures for a glycosylated product with multiple mechanisms of inactivation.Q51038672
Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture.Q51795547
Cell death in bioreactors: a role for apoptosis.Q52692588
Effects of ammonia and lactate on growth, metabolism, and productivity of BHK cellsQ58754717
P433issue9
P921main subjectautophagyQ288322
P304page(s)2182-2192
P577publication date2011-05-07
P1433published inBiotechnology and BioengineeringQ4915339
P1476titleAutophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: effect of nutrient supplementation
P478volume108

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cites work (P2860)
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