An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling

scientific article published on August 2011

An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/IJC.26124
P698PubMed publication ID21480224
P5875ResearchGate publication ID51039140

P50authorBeate K StraubQ45373493
P2093author name stringJudith Lehmann-Koch
Michael Boutros
Wilfried Roth
Christina Falschlehner
Dorothee Nickles
Marie Metzig
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Is NF-kappaB a good target for cancer therapy? Hopes and pitfallsQ24570128
CellProfiler: image analysis software for identifying and quantifying cell phenotypesQ24676898
Immunity, Inflammation, and CancerQ27861048
Tumor necrosis factor receptor-associated factors (TRAFs)Q28199382
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaBQ28201706
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancerQ28253300
Regulation and function of IKK and IKK-related kinasesQ28268930
A genomic and functional inventory of deubiquitinating enzymesQ28284911
Good cop, bad cop: the different faces of NF-kappaBQ28291669
Shared principles in NF-kappaB signalingQ29547234
Activators and target genes of Rel/NF-kappaB transcription factorsQ29547882
An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.Q33223553
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Signal transduction by tumor necrosis factor and its relativesQ34341941
NF-kappaB and breast cancerQ34995649
NF-kappaB: tumor promoter or suppressor?Q35753163
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NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosisQ35971557
A20 inhibits NF-kappaB activation by dual ubiquitin-editing functionsQ36011021
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathwaysQ36089051
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NF-kappaB and cancer: mechanisms and targetsQ36468005
TNFalpha blockade in human diseases: mechanisms and future directionsQ36536886
Deubiquitinating enzymes as novel anticancer targetsQ36536984
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Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activationQ37028019
Ubiquitin-mediated regulation of TNFR1 signalingQ37178522
Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancerQ37376029
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survivalQ39761203
The isopeptidase USP2a protects human prostate cancer from apoptosisQ40236434
Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.Q40400391
Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteasesQ40573595
Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signalingQ42920131
Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2.Q45092993
Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survivalQ46253089
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastomaQ46866555
Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular CarcinomaQ58619568
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
TNFQ18032037
P304page(s)607-618
P577publication date2011-08-01
P1433published inInternational Journal of CancerQ332492
P1476titleAn RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling
P478volume129

Reverse relations

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