Dexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity.

scientific article published on 21 July 2016

Dexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.3A0316-125R
P932PMC publication ID5109997
P698PubMed publication ID27443878

P50authorDaniel AbebayehuQ87091461
Carole A OskeritzianQ87091469
P2093author name stringJohn J Ryan
Bianca Baker
Brian O Barnstein
Alena P Chumanevich
Amina Abdul Qayum
Andrew J Spence
Anuya Paranjape
Jamie Josephine Avila McLeod
Marcela T Taruselli
Gurjas S Bajaj
Oksana Chernushevich
P2860cites workIL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokinesQ24294720
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.Q24537701
Development, migration, and survival of mast cellsQ24549674
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptorQ24561876
The role of IL-33 and mast cells in allergy and inflammationQ26783420
Inhibition by glucocorticoids of the mast cell-dependent weal and flare response in human skin in vivoQ28345893
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1Q28366337
Dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mast cellsQ28571913
Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathwayQ28587516
Molecular mechanisms of spontaneous and directed mast cell motilityQ30525710
IL-33 Is Produced by Mast Cells and Regulates IgE-Dependent InflammationQ33651095
Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT.Q33895733
IL-33/ST2 axis promotes mast cell survival via BCLXL.Q33925929
The IL-33/ST2 pathway: therapeutic target and novel biomarkerQ34776884
Amplification of cytokine production through synergistic activation of NFAT and AP-1 following stimulation of mast cells with antigen and IL-33Q34895161
IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis.Q35036030
IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalkQ35565295
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivoQ35575987
Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects.Q36553647
IL-33 exacerbates antigen-induced arthritis by activating mast cellsQ36800502
Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cellsQ36990456
Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticariaQ37273100
Role of IL-33 in inflammation and diseaseQ37922810
IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy.Q38256319
Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.Q39457701
Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoidQ39947300
Regulation of mouse mast cell surface Fc epsilon RI expression by dexamethasoneQ40795700
The thrombogenic hypothesis and its implicationsQ40831957
Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cellsQ41167760
Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.Q41468527
Dexamethasone inhibits maturation, cytokine production and Fc epsilon RI expression of human cord blood-derived mast cellsQ42522030
FcepsilonRI-mediated mast cell migration: signaling pathways and dependence on cytosolic free Ca2+ concentrationQ42569152
Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthmaQ42981972
IL-33 exacerbates autoantibody-induced arthritisQ43170043
Human skin-derived mast cells can proliferate while retaining their characteristic functional and protease phenotypesQ43551017
Sensitized mast cells migrate toward the antigen: a response regulated by p38 mitogen-activated protein kinase and Rho-associated coiled-coil-forming protein kinaseQ43699080
Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependentQ44427614
Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE.Q48240026
Interleukin-33 exacerbates allergic bronchoconstriction in the mice via activation of mast cells.Q51660722
Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.Q53085315
Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses.Q53579877
IL-33 induces skin inflammation with mast cell and neutrophil activationQ57231942
IL-33 can promote survival, adhesion and cytokine production in human mast cellsQ57273112
Regulation of mediator release from mouse bone marrow-derived mast cells by glucocorticoidsQ67918527
Dexamethasone or cyclosporin A suppress mast cell-leukocyte cytokine cascades. Multiple mechanisms of inhibition of IgE- and mast cell-dependent cutaneous inflammation in the mouseQ72412489
Inhibition by dexamethasone of antigen-induced c-Jun N-terminal kinase activation in rat basophilic leukemia cellsQ77484047
Studies on dexamethasone, a new synthetic steroid, in rheurheumatoid arthritis: a preliminary report; adrenal cortical, metabolic and early clinical effectsQ78266115
A decade of anti-inflammatory steroids, from cortisone to dexamethasone. SummaryQ79178610
P433issue6
P921main subjectmast cellQ191989
dexamethasoneQ422252
P304page(s)1395-1404
P577publication date2016-07-21
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleDexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity
P478volume100

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cites work (P2860)
Q61796660A Novel Synthetic Steroid of 2β,3α,5α-Trihydroxy-androst-6-one Alleviates the Loss of Rat Retinal Ganglion Cells Caused by Acute Intraocular Hypertension via Inhibiting the Inflammatory Activation of Microglia
Q54213225Controlling Mast Cell Activation and Homeostasis: Work Influenced by Bill Paul That Continues Today.
Q45064301Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IL-33-induced cytokine production in primary mouse mast cells.
Q45068864Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IgE-mediated mast cell activation through attenuation of NFκB and AP-1 transcription
Q88452579Efficacy of long-term intralesional triamcinolone in Morbihan's disease and its possible association with mast cell infiltration
Q50193724Involvement of the Negative Feedback of IL-33 Signaling in the Anti-Inflammatory Effect of Electro-acupuncture on Allergic Contact Dermatitis via Targeting MicroRNA-155 in Mast Cells
Q90884836Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps

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