Pitx2c modulates cardiac-specific transcription factors networks in differentiating cardiomyocytes from murine embryonic stem cells.

scientific article published on 9 March 2011

Pitx2c modulates cardiac-specific transcription factors networks in differentiating cardiomyocytes from murine embryonic stem cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1159/000323533
P8608Fatcat IDrelease_uzmlq37qvne3nbyswayo2vwd7q
P698PubMed publication ID21389672

P50authorDiego FrancoQ41422930
Francisco NavarroQ64351544
Francisco Hernández-TorresQ80805808
P2093author name stringGary E Lyons
Ana Chinchilla
Estefanía Lozano-Velasco
Amelia E Aránega
Sergio Martínez-Fernández
P2860cites workGlobal transcriptome analysis of murine embryonic stem cell-derived cardiomyocytesQ21999567
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formationQ24675337
Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart fieldQ28512364
Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardiumQ28586689
Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programsQ28588668
Pitx2c overexpression promotes cell proliferation and arrests differentiation in myoblastsQ28590078
Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac graftsQ34387398
The anterior heart-forming field: voyage to the arterial pole of the heartQ34586950
Heart development: molecular insights into cardiac specification and early morphogenesisQ35143131
Expression and regulation of the atrial natriuretic factor encoding gene Nppa during development and disease.Q36185729
Developmental regulation of myosin gene expression in mouse cardiac muscleQ36224282
Transcriptional pathways in second heart field developmentQ36727615
Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.Q38293562
Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiationQ39761766
The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targetingQ39786564
Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment.Q40632630
PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5.Q40656003
Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currentsQ41451209
Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity.Q43162939
Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic developmentQ46350581
Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetryQ47904024
Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice.Q52140742
P433issue5
P304page(s)349-362
P577publication date2011-03-09
P1433published inCells Tissues OrgansQ2167221
P1476titlePitx2c modulates cardiac-specific transcription factors networks in differentiating cardiomyocytes from murine embryonic stem cells
P478volume194

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cites work (P2860)
Q85215749Association of growth/differentiation factor 1 gene polymorphisms with the risk of congenital heart disease in the Chinese Han population
Q47133065Hyperthyroidism, but not hypertension, impairs PITX2 expression leading to Wnt-microRNA-ion channel remodeling
Q88651515Interplay between cardiac transcription factors and non-coding RNAs in predisposing to atrial fibrillation
Q40397117Novel association of polymorphic genetic variants with predictors of outcome of catheter ablation in atrial fibrillation: new directions from a prospective study (DECAF).
Q30040543PITX2 Loss-of-Function Mutation Contributes to Congenital Endocardial Cushion Defect and Axenfeld-Rieger Syndrome
Q37121395PITX2c loss-of-function mutations responsible for congenital atrial septal defects
Q30439057Pitx2-mediated cardiac outflow tract remodeling
Q51861214Pitx2c modulates Pax3+/Pax7+ cell populations and regulates Pax3 expression by repressing miR27 expression during myogenesis.
Q34475283Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development
Q37395274Prevalence and spectrum of PITX2c mutations associated with congenital heart disease
Q50130661RHOA-ROCK signalling is necessary for lateralization and differentiation of the developing sinoatrial node
Q38215321The functional diversity of essential genes required for mammalian cardiac development.
Q36025564Transgenic insights linking pitx2 and atrial arrhythmias