| scholarly article | Q13442814 |
| P50 | author | Jayne A. Wright | Q47164167 |
| Liam A Ridge | Q59935820 | ||
| P2093 | author name string | Christopher Clowes | |
| Kathryn E Hentges | |||
| Emma Barnes | |||
| Michael G S Boylan | |||
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| The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer | Q40609387 | ||
| CHAMP, a novel cardiac-specific helicase regulated by MEF2C. | Q40703404 | ||
| Nkx2-5 activity is essential for cardiomyogenesis | Q40783312 | ||
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| A heart segmental defect in the anterior-posterior axis of a transgenic mutant mouse | Q40893602 | ||
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| Requirement for neuregulin receptor erbB2 in neural and cardiac development | Q41269625 | ||
| Structural development of endocardial cushions | Q41514696 | ||
| Inactivation of erythropoietin leads to defects in cardiac morphogenesis | Q41679719 | ||
| N-cadherin is required for neural crest remodeling of the cardiac outflow tract | Q41834366 | ||
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| PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. | Q42491526 | ||
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| Arterial pole progenitors interpret opposing FGF/BMP signals to proliferate or differentiate. | Q42504346 | ||
| Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice. | Q42524186 | ||
| The FGF-BMP Signaling Axis Regulates Outflow Tract Valve Primordium Formation by Promoting Cushion Neural Crest Cell Differentiation | Q42671011 | ||
| Functional interaction between Foxd3 and Pax3 in cardiac neural crest development | Q42722333 | ||
| Analysis of the proepicardium-epicardium transition during the malformation of the RXRalpha-/- epicardium | Q42734016 | ||
| The G3 Domain of Versican Enhances Cell Proliferation via Epidermial Growth Factor-like Motifs | Q42827501 | ||
| Proteolytic cleavage of versican during cardiac cushion morphogenesis | Q42913840 | ||
| Mouse mutagenesis with the chemical supermutagen ENU. | Q42941345 | ||
| Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. | Q42945812 | ||
| Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor | Q43116436 | ||
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| RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. | Q46123728 | ||
| The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field | Q46196456 | ||
| Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development | Q46350581 | ||
| Right ventricular myocardium derives from the anterior heart field | Q47290410 | ||
| Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. | Q47623642 | ||
| Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. | Q47624561 | ||
| The clonal origin of myocardial cells in different regions of the embryonic mouse heart | Q47640178 | ||
| The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle. | Q47857818 | ||
| Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome | Q47955346 | ||
| Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis | Q48132703 | ||
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| Perlecan is critical for heart stability. | Q48975311 | ||
| Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse | Q28590252 | ||
| Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium | Q28590420 | ||
| Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis | Q28590588 | ||
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| MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field | Q28591512 | ||
| The bHLH Factors, dHAND and eHAND, Specify Pulmonary and Systemic Cardiac Ventricles Independent of Left–Right Sidedness | Q28591545 | ||
| Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract | Q28591930 | ||
| Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND | Q28592248 | ||
| Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis | Q28592331 | ||
| The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development | Q28592694 | ||
| Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation | Q28592747 | ||
| T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis | Q28592753 | ||
| The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene | Q28593105 | ||
| A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease | Q28594121 | ||
| Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart | Q28594286 | ||
| Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development | Q28594374 | ||
| GATA4 is essential for formation of the proepicardium and regulates cardiogenesis | Q28594766 | ||
| Building the mammalian heart from two sources of myocardial cells | Q29618590 | ||
| Gene regulatory networks in the evolution and development of the heart | Q29619086 | ||
| The effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on protein-protein interactions. | Q30352189 | ||
| Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression | Q30444477 | ||
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| New insights into behaviour using mouse ENU mutagenesis | Q30463349 | ||
| Cardiac fibroblast: the renaissance cell | Q30467800 | ||
| Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest | Q30478829 | ||
| Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice | Q30497991 | ||
| Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations | Q30502995 | ||
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| Regional variation in the density of essential genes in mice | Q33283731 | ||
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| Calreticulin: one protein, one gene, many functions. | Q33776572 | ||
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| Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation | Q34637818 | ||
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| Rapid identification of a disease allele in mouse through whole genome sequencing and bulk segregation analysis | Q34714895 | ||
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| Transcriptional control of the calreticulin gene in health and disease | Q34819505 | ||
| Early signals in cardiac development. | Q34872418 | ||
| What cardiovascular defect does my prenatal mouse mutant have, and why? | Q35025207 | ||
| Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation | Q35095178 | ||
| Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling | Q35162957 | ||
| Tbx20 Transcription Factor Is a Downstream Mediator for Bone Morphogenetic Protein-10 in Regulating Cardiac Ventricular Wall Development and Function | Q35378201 | ||
| Essential roles of Her2/erbB2 in cardiac development and function | Q35641803 | ||
| FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart | Q35792899 | ||
| Architectural plan for the heart: early patterning and delineation of the chambers and the nodes. | Q35982225 | ||
| Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development | Q36064260 | ||
| Cell biology of cardiac cushion development. | Q36083465 | ||
| Calreticulin is essential for cardiac development | Q36288304 | ||
| Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse | Q28296363 | ||
| Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system | Q28304868 | ||
| Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus | Q28504737 | ||
| Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition | Q28505095 | ||
| Transforming growth factor beta-SMAD2 signaling regulates aortic arch innervation and development | Q28505326 | ||
| Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function | Q28505330 | ||
| Serum response factor is essential for mesoderm formation during mouse embryogenesis | Q28505560 | ||
| The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner | Q28505600 | ||
| TheCspg2Gene, Disrupted in thehdfMutant, Is Required for Right Cardiac Chamber and Endocardial Cushion Formation | Q28505731 | ||
| BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart | Q28505957 | ||
| Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects | Q28506220 | ||
| Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development | Q28507437 | ||
| p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium | Q28507727 | ||
| Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development | Q28508308 | ||
| CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway | Q28508312 | ||
| Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice | Q28508475 | ||
| Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum | Q28508556 | ||
| The transcription factor NF-ATc is essential for cardiac valve formation | Q28508583 | ||
| Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor | Q28509287 | ||
| The transcriptional control of trunk neural crest induction, survival, and delamination | Q28511755 | ||
| The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism | Q28511780 | ||
| MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube | Q28511812 | ||
| Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis | Q28511878 | ||
| Foxh1 is essential for development of the anterior heart field | Q28511957 | ||
| A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development | Q28512323 | ||
| Restricted inactivation of serum response factor to the cardiovascular system | Q28512435 | ||
| MesP1 and MesP2 are essential for the development of cardiac mesoderm | Q28512582 | ||
| The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo | Q28512702 | ||
| Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin | Q28512937 | ||
| The Combinatorial Activities of Nkx2.5 and dHAND Are Essential for Cardiac Ventricle Formation | Q28513199 | ||
| Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development | Q28513337 | ||
| Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets | Q28513648 | ||
| Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation. | Q28565149 | ||
| Structure and function of myosin filaments | Q36431052 | ||
| Cardiac titin: structure, functions and role in disease | Q36563688 | ||
| Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects | Q36618064 | ||
| Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice | Q36638658 | ||
| Role of bone morphogenetic proteins in cardiac differentiation | Q36691904 | ||
| Combinatorial signaling in the heart orchestrates cardiac induction, lineage specification and chamber formation. | Q36712630 | ||
| Structural basis for the regulation of muscle contraction by troponin and tropomyosin | Q36791585 | ||
| Sense and stretchability: the role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction | Q36809320 | ||
| GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. | Q36846038 | ||
| Signal transduction in early heart development (I): cardiogenic induction and heart tube formation | Q36869627 | ||
| Signal transduction in early heart development (II): ventricular chamber specification, trabeculation, and heart valve formation. | Q36869632 | ||
| Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. | Q36952843 | ||
| Assembly and maintenance of the sarcomere night and day. | Q37002256 | ||
| Sarcomeric proteins and inherited cardiomyopathies. | Q37023249 | ||
| Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation | Q37046062 | ||
| Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. | Q37070593 | ||
| Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal | Q37080793 | ||
| Structural basis for the activation of muscle contraction by troponin and tropomyosin | Q37218670 | ||
| Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay | Q37257847 | ||
| Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene | Q37296387 | ||
| Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development | Q37348318 | ||
| Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice | Q37386882 | ||
| An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart | Q37407385 | ||
| Epicardial control of myocardial proliferation and morphogenesis | Q37412452 | ||
| Heart valve development: regulatory networks in development and disease | Q37421779 | ||
| Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis | Q37597645 | ||
| Transcriptional regulation of heart valve progenitor cells. | Q37663819 | ||
| Sarcomere control mechanisms and the dynamics of the cardiac cycle | Q37751888 | ||
| Vascularizing the heart | Q37833832 | ||
| BMP signaling in congenital heart disease: New developments and future directions | Q37850773 | ||
| Extracellular matrix and heart development | Q37880711 | ||
| Metabolic network reconstruction: advances in in silico interpretation of analytical information | Q37961354 | ||
| Chamber formation and morphogenesis in the developing mammalian heart | Q28566310 | ||
| Cooperative interaction between the basic helix-loop-helix transcription factor dHAND and myocyte enhancer factor 2C regulates myocardial gene expression | Q28581318 | ||
| Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo | Q28584770 | ||
| BMP type II receptor is required for gastrulation and early development of mouse embryos | Q28586233 | ||
| GATA4 transcription factor is required for ventral morphogenesis and heart tube formation | Q28586495 | ||
| BMP10 is essential for maintaining cardiac growth during murine cardiogenesis | Q28586844 | ||
| Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment | Q28587029 | ||
| Altered apoptosis pattern during pharyngeal arch artery remodelling is associated with aortic arch malformations in Tgfbeta2 knock-out mice | Q28587471 | ||
| Cardiac neural crest and outflow tract defects in Lrp6 mutant mice | Q28587527 | ||
| The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo | Q28587737 | ||
| Multiple essential functions of neuregulin in development | Q28587914 | ||
| Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development | Q28587943 | ||
| Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis | Q28587987 | ||
| M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere | Q28588265 | ||
| Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo | Q28588360 | ||
| Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality | Q28589037 | ||
| Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation | Q28589469 | ||
| The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis | Q28590046 | ||
| ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level | Q50502388 | ||
| Staging of the commitment of murine cardiac cell progenitors | Q51076071 | ||
| Murine cardiac progenitor cells require visceral embryonic endoderm and primitive streak for terminal differentiation | Q51100426 | ||
| Proteins and domains vary in their tolerance of non-synonymous single nucleotide polymorphisms (nsSNPs). | Q51273303 | ||
| Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H). | Q51829029 | ||
| Developmental origin, growth, and three-dimensional architecture of the atrioventricular conduction axis of the mouse heart. | Q51903075 | ||
| Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo | Q51951634 | ||
| The expanding role for retinoid signaling in heart development | Q51951890 | ||
| Cardiovascular development and the colonizing cardiac neural crest lineage | Q51981254 | ||
| Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart. | Q52004210 | ||
| Epicardial development in the rat: a new perspective | Q52006616 | ||
| Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4. | Q52178778 | ||
| Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement | Q52184549 | ||
| Cardiac and Extracardiac Expression of Csx/Nkx2.5 Homeodomain Protein | Q52187531 | ||
| Expression Pattern of Connexin Gene Products at the Early Developmental Stages of the Mouse Cardiovascular System | Q52192878 | ||
| Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis | Q52204129 | ||
| Chapter 9. Development of coronary vessels. | Q54506625 | ||
| Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development. | Q55282875 | ||
| Formation of the ventricles. | Q55416364 | ||
| The development of the myocardium and endocardium in mouse embryos. Fusion of two heart tubes? | Q68098904 | ||
| Murine FGFR-1 is required for early postimplantation growth and axial organization | Q71989885 | ||
| Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development | Q72093904 | ||
| Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants | Q72678188 | ||
| The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation | Q73370325 | ||
| Chemotactic migration of mesencephalic neural crest cells in the mouse | Q73519299 | ||
| The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm | Q77153201 | ||
| Differential growth and multicellular villi direct proepicardial translocation to the developing mouse heart | Q80145787 | ||
| Wnt5a is required for cardiac outflow tract septation in mice | Q80362379 | ||
| Essential role of Smad4 in maintaining cardiomyocyte proliferation during murine embryonic heart development | Q81297429 | ||
| Epicardium-derived cells enhance proliferation, cellular maturation and alignment of cardiomyocytes | Q84591100 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 8 | |
| P921 | main subject | mammal | Q7377 |
| circulatory system | Q11068 | ||
| regulation of gene expression | Q411391 | ||
| eukaryote | Q19088 | ||
| biodiversity | Q47041 | ||
| P304 | page(s) | 713-737 | |
| P577 | publication date | 2014-06-24 | |
| 2014-08-01 | |||
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Genesis | Q5532784 |
| P1476 | title | The functional diversity of essential genes required for mammalian cardiac development | |
| P478 | volume | 52 |
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