Functional interaction between Foxd3 and Pax3 in cardiac neural crest development

scientific article published on December 22, 2010

Functional interaction between Foxd3 and Pax3 in cardiac neural crest development is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/DVG.20686
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fdvg.20686
https://doi.org/10.1002/dvg.20686
https://europepmc.org/articles/PMC3082627
https://europepmc.org/articles/pmc3082627?pdf=render
https://europepmc.org/articles/PMC3082627?pdf=render
https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvg.20686
P932PMC publication ID3082627
P698PubMed publication ID21254333
P5875ResearchGate publication ID49773806

P50authorPatricia LaboskyQ106396422
P2093author name stringBrian L. Nelms
Elise R. Pfaltzgraff
P2860cites workCre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locusQ24797230
Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
Fate of the mammalian cardiac neural crestQ28139176
Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tubeQ28504997
Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant miceQ28505985
Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryoQ28506803
Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in miceQ28506846
The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fateQ28509858
Pax3 functions at a nodal point in melanocyte stem cell differentiationQ28587774
Foxd3 is required in the trophoblast progenitor cell lineage of the mouse embryoQ28592381
Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the splotch (Sp(2H))/Pax3 mouse mutantQ28594842
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinaseQ29615040
Mesenchymal derivatives of the neural crest: analysis of chimaeric quail and chick embryosQ31039117
Chordin is a modifier of tbx1 for the craniofacial malformations of 22q11 deletion syndrome phenotypes in mouseQ33413046
Velo-cardio-facial syndrome: 30 Years of studyQ33585486
Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activityQ34368732
Molecular basis of splotch and Waardenburg Pax-3 mutationsQ35191281
Cooperation between the PDGF receptors in cardiac neural crest cell migrationQ36088538
Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of PediaQ36829213
Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart diseaseQ37077784
Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crestQ37124965
Alteration of cardiogenesis after neural crest ablationQ37934346
Neural crest function in thymus development.Q38216430
Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectodermQ38327715
Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3Q39957518
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.Q41080686
FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanismQ43130524
Requirement for Foxd3 in the maintenance of neural crest progenitorsQ43139378
Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryosQ43180159
Neural crest ontogeny during secondary neurulation: a gene expression pattern study in the chick embryoQ43926584
Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryosQ44120325
Pulmonary hypertension after operations for congenital heart disease: analysis of risk factors and managementQ45239967
Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant effectQ47265999
The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse developmentQ48017150
A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical regionQ48056033
Pax3 regulates Wnt1 expression via a conserved binding site in the 5' proximal promoterQ51576424
Cardiovascular development and the colonizing cardiac neural crest lineageQ51981254
Migration of cardiac neural crest cells in Splotch embryosQ52169435
Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporterQ52194454
Normal embryonic development and cardiac morphogenesis in mice with Wnt1-Cre-mediated deletion of connexin43Q58194340
The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 geneQ70497127
The Splotch (Sp1H) and Splotch-delayed (Spd) alleles: differential phenotypic effects on neural crest and limb musculatureQ70763083
Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutantQ73116619
NEW SPLOTCH ALLELES IN THE MOUSEQ76854243
Temporal-spatial ablation of neural crest in the mouse results in cardiovascular defectsQ80145773
Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivativesQ81729304
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)10-23
P577publication date2010-12-22
P1433published inGenesisQ5532784
P1476titleFunctional interaction between Foxd3 and Pax3 in cardiac neural crest development
P478volume49

Reverse relations

cites work (P2860)
Q35605185Cardiovascular defects in a mouse model of HOXA1 syndrome
Q27015114Connecting teratogen-induced congenital heart defects to neural crest cells and their effect on cardiac function
Q36807495Early development of the thymus in Xenopus laevis.
Q35782972Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors
Q58590875Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion
Q39485917Ground-State Transcriptional Requirements for Skin-Derived Precursors
Q50467900Hypoxia and hyperoxia differentially control proliferation of rat neural crest stem cells via distinct regulatory pathways of the HIF1α-CXCR4 and TP53-TPM1 proteins
Q58588198Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency
Q35590815Loss of Foxd3 results in decreased β-cell proliferation and glucose intolerance during pregnancy
Q36065213PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma
Q36178682Partitioning the heart: mechanisms of cardiac septation and valve development
Q35127152Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation
Q61453545Serum Fork-Head Box D3 (FOXD3) Expression Is Down-Regulated in and Associated with Diagnosis of Patients with Non-Small Cell Lung Cancer
Q39757672Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population
Q38215321The functional diversity of essential genes required for mammalian cardiac development.
Q39189740Thymus: Conservation in evolution
Q37602534Transcriptional targets of Foxd3 in murine ES cells

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