| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M301648200 |
| P698 | PubMed publication ID | 14662776 |
| P2093 | author name string | Robert J Schwartz | |
| Xin-Hua Feng | |||
| Xuan Chi | |||
| Carl O Brown | |||
| Eduardo Garcia-Gras | |||
| Manabu Shirai | |||
| P2860 | cites work | OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways | Q22011195 |
| Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation | Q24291385 | ||
| Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes | Q24310852 | ||
| Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription | Q24315851 | ||
| Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4 | Q24554412 | ||
| Smads bind directly to the Jun family of AP-1 transcription factors | Q24685193 | ||
| Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter | Q28146024 | ||
| Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors | Q28203420 | ||
| Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B) | Q28216177 | ||
| The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3 | Q28276517 | ||
| NK-2 homeobox genes and heart development | Q28290183 | ||
| The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo | Q28512702 | ||
| Smad2 Signaling in Extraembryonic Tissues Determines Anterior-Posterior Polarity of the Early Mouse Embryo | Q28586864 | ||
| Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis | Q28592331 | ||
| GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression | Q33774042 | ||
| Cardiac and skeletal muscle development in P19 embryonal carcinoma cells | Q33819926 | ||
| The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. | Q34066369 | ||
| Signaling of transforming growth factor-beta family members through Smad proteins | Q34098846 | ||
| Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation | Q34675849 | ||
| Genetic analysis of the mammalian transforming growth factor-beta superfamily | Q35017076 | ||
| Tempting fate: BMP signals for cardiac morphogenesis | Q35027080 | ||
| The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation | Q35205960 | ||
| Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm | Q35206923 | ||
| The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice | Q36008239 | ||
| Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. | Q36258971 | ||
| Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5. | Q36709632 | ||
| Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain | Q38305512 | ||
| Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta | Q40370863 | ||
| Physical and Functional Interaction between GATA-3 and Smad3 Allows TGF-β Regulation of GATA Target Genes | Q40757292 | ||
| BMP signaling regulates Nkx2‐5 activity during cardiomyogenesis | Q40765157 | ||
| Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation. | Q40806167 | ||
| A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells | Q40862597 | ||
| Interaction of Smad complexes with tripartite DNA-binding sites | Q40942963 | ||
| Smad2 role in mesoderm formation, left–right patterning and craniofacial development | Q41027581 | ||
| Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo | Q47072261 | ||
| Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site | Q47616447 | ||
| Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer | Q47724219 | ||
| Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region | Q52121452 | ||
| Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes | Q52141297 | ||
| Lack of regulation in the heart forming region of avian embryos | Q52179106 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10659-10669 | |
| P577 | publication date | 2003-12-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer | |
| P478 | volume | 279 |
| Q125290111 | A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors |
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| Q34341781 | BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH. |
| Q28593688 | Baf60c is essential for function of BAF chromatin remodelling complexes in heart development |
| Q42025588 | Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes |
| Q29618590 | Building the mammalian heart from two sources of myocardial cells |
| Q37649103 | CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice |
| Q37002682 | Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis |
| Q48084646 | CisView: a browser and database of cis-regulatory modules predicted in the mouse genome. |
| Q34015900 | Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules |
| Q28483640 | Congenital Heart Disease–Causing Gata4 Mutation Displays Functional Deficits In Vivo |
| Q38756719 | Constitutive Expression of GATA4 Dramatically Increases the Cardiogenic Potential of D3 Mouse Embryonic Stem Cells. |
| Q51931039 | Coordinating the timing of cardiac precursor development during gastrulation: a new role for Notch signaling |
| Q39948025 | Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene |
| Q51944236 | Developmental signaling in myocardial progenitor cells: a comprehensive view of Bmp- and Wnt/beta-catenin signaling |
| Q36225114 | Differentiation pathways in human embryonic stem cell-derived cardiomyocytes |
| Q36404968 | Early cardiac development: a view from stem cells to embryos |
| Q39862975 | Enhanced expression of transcription factor GATA-4 in inflammatory bowel disease and its possible regulation by TGF-beta1. |
| Q81297429 | Essential role of Smad4 in maintaining cardiomyocyte proliferation during murine embryonic heart development |
| Q36545329 | Evolutionary conservation of Nkx2.5 autoregulation in the second heart field |
| Q34308498 | Examining the cardiac NK-2 genes in early heart development. |
| Q80826901 | Expression of Id1 in adult, regenerating and developing pancreas |
| Q37481055 | Finding partners: how BMPs select their targets |
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| Q45875521 | HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus |
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| Q37497678 | Heart genetics in a small package, exploiting the condensed genome of Ciona intestinalis |
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| Q34274633 | Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5 |
| Q99238339 | Integrative Analysis Revealing Human Heart-Specific Genes and Consolidating Heart-Related Phenotypes |
| Q39645500 | LYRM1, a Gene that Promotes Proliferation and Inhibits Apoptosis during Heart Development |
| Q37613372 | Lrrc10 is a novel cardiac-specific target gene of Nkx2-5 and GATA4. |
| Q37976513 | Mechanisms of Cardiogenesis in Cardiovascular Progenitor Cells |
| Q39635390 | Mitogen‐activated protein kinase in endothelin‐1‐induced cardiac differentiation of mouse embryonic stem cells |
| Q49998541 | Molecular Basis for Dysregulated Activation of NKX2-5 in the Vascular Remodeling of Systemic Sclerosis |
| Q28509654 | Morphogenesis of the right ventricle requires myocardial expression of Gata4 |
| Q30481126 | Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes |
| Q33596324 | Mulan: multiple-sequence local alignment and visualization for studying function and evolution |
| Q55671555 | Mutations of the GATA4 and NKX2.5 genes in Chinese pediatric patients with non-familial congenital heart disease |
| Q30525396 | Myocardin regulates BMP10 expression and is required for heart development |
| Q36890625 | NADPH oxidase 4 regulates cardiomyocyte differentiation via redox activation of c-Jun protein and the cis-regulation of GATA-4 gene transcription |
| Q39933728 | NFAT directly regulates Nkx2-5 transcription during cardiac cell differentiation |
| Q24315020 | NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes |
| Q24656564 | Notch1 regulates the fate of cardiac progenitor cells |
| Q35862534 | Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5. |
| Q31060298 | PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation |
| Q34501443 | Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells |
| Q35021865 | Phosphorylation of Shox2 is required for its function to control sinoatrial node formation. |
| Q31133691 | Prediction and validation of protein-protein interactors from genome-wide DNA-binding data using a knowledge-based machine-learning approach |
| Q30435396 | RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression |
| Q35757916 | Re-employment of developmental transcription factors in adult heart disease |
| Q52038711 | Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling |
| Q36512426 | Role of the GATA family of transcription factors in endocrine development, function, and disease |
| Q28594857 | Sertad1 encodes a novel transcriptional co-activator of SMAD1 in mouse embryonic hearts |
| Q28087290 | Signaling Pathways and Gene Regulatory Networks in Cardiomyocyte Differentiation |
| Q37413451 | T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. |
| Q43071534 | TGF-beta1 enhances cardiomyogenic differentiation of skeletal muscle-derived adult primitive cells |
| Q38215321 | The functional diversity of essential genes required for mammalian cardiac development. |
| Q38023555 | Transcription Factors in Heart: Promising Therapeutic Targets in Cardiac Hypertrophy |
| Q24293493 | Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development |
| Q47878462 | Transcription factors-Intricate players of the bone morphogenetic protein signaling pathway |
| Q37124595 | Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development |
| Q38548499 | Unique functions of Gata4 in mouse liver induction and heart development |
| Q30481617 | Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression |
| Q58603355 | smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish |
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