GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.

scientific article

GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKH727
P932PMC publication ID514362
P698PubMed publication ID15302915
P5875ResearchGate publication ID8408078

P50authorSteven GoossensQ38545837
P2093author name stringFrans van Roy
Geert Berx
Bram De Craene
Griet Vanpoucke
Barbara Gilbert
P2860cites workMyocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cellsQ22008552
OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathwaysQ22011195
alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesionQ24291766
GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1Q24313004
GATA-dependent recruitment of MEF2 proteins to target promotersQ24599616
Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain geneQ24611410
Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skinQ28203751
Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heartQ28214586
The failing heartQ28216352
Poorly differentiated colon carcinoma cell lines deficient in alpha-catenin expression express high levels of surface E-cadherin but lack Ca(2+)-dependent cell-cell adhesionQ28247836
A Mutation in α-Catenin Disrupts Adhesion in Clone A Cells Without Perturbing its Actin and β-Catenin Binding ActivityQ28284597
Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteinsQ28294155
The Cardiac Tissue-Restricted Homeobox Protein Csx/Nkx2.5 Physically Associates with the Zinc Finger Protein GATA4 and Cooperatively Activates Atrial Natriuretic Factor Gene ExpressionQ28504813
Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testisQ28512519
Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expressionQ28570255
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesisQ28592331
MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence dataQ29547902
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyteQ29620367
Fine mapping of the -T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigreesQ33719301
Abnormalities of the genitourinary tract in female mice lacking GATA5.Q33964653
The "final common pathway" hypothesis and inherited cardiovascular disease. The role of cytoskeletal proteins in dilated cardiomyopathyQ33974762
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.Q34066369
Genomic structures of the human and murine corin genes and functional GATA elements in their promotersQ34142432
Sequence and chromosomal context effects on variegated expression of keratin 5/lacZ constructs in stratified epithelia of transgenic mice.Q34612585
Unravelling heterochromatin: competition between positive and negative factors regulates accessibilityQ34669695
Heart development: molecular insights into cardiac specification and early morphogenesisQ35143131
Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma lineQ36234689
Protein kinase C activation upregulates intercellular adhesion of alpha-catenin-negative human colon cancer cell variants via induction of desmosomesQ36262030
Expression of Wild-Type α-Catenin Protein in Cells with a Mutant α-Catenin Gene Restores Both Growth Regulation and Tumor Suppressor ActivitiesQ36570113
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's diseaseQ40568200
A fluorescent reporter gene as a marker for ventricular specification in ES-derived cardiac cellsQ40865173
Chromosome 5 suppresses tumorigenicity of PC3 prostate cancer cells: correlation with re-expression of alpha-catenin and restoration of E-cadherin functionQ41278483
Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells.Q41536930
Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesivenessQ41598631
Cardiac expression of the Na(+)/Ca(2+) exchanger NCX1 is GATA factor dependentQ41679635
Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatusQ44364076
Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathyQ48258705
GATA factors differentially activate multiple gonadal promoters through conserved GATA regulatory elementsQ49023691
The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cellsQ49171197
GATA-4 regulates cardiac morphogenesis through transactivation of the N-cadherin geneQ52096891
Myocyte-specific enhancer binding factor 2C expression in human brain developmentQ72119328
Identification of cis-acting DNA elements required for expression of the human cardiac troponin I gene promoterQ73396257
P433issue14
P1104number of pages11
P304page(s)4155-4165
P577publication date2004-08-09
P1433published inNucleic Acids ResearchQ135122
P1476titleGATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.
P478volume32

Reverse relations

cites work (P2860)
Q37877619Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest.
Q38221499Alterations in cell adhesion proteins and cardiomyopathy
Q28587943Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development
Q40370696Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.
Q38928722EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner
Q84766369Functional Gene Expression Analysis of Tissue-Specific Isoforms of Mef2c
Q36977728GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
Q37625006Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome
Q35851556Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
Q40125967MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells
Q37976513Mechanisms of Cardiogenesis in Cardiovascular Progenitor Cells
Q37296387Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene
Q38152548Microenvironmental regulation of cancer metastasis by miRNAs.
Q21245767Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
Q28395671New functions for alpha-catenins in health and disease: from cancer to heart regeneration
Q42736171Revealing global regulatory perturbations across human cancers
Q24814569SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
Q27341940TMEM43 mutation p.S358L alters intercalated disc protein expression and reduces conduction velocity in arrhythmogenic right ventricular cardiomyopathy
Q26746972Targeting microRNAs as key modulators of tumor immune response
Q49593660The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets
Q54680284The STOX1 genotype associated with pre-eclampsia leads to a reduction of trophoblast invasion by alpha-T-catenin upregulation.
Q38215321The functional diversity of essential genes required for mammalian cardiac development.
Q36326979Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells
Q33843316Vertebrate paralogous MEF2 genes: origin, conservation, and evolution
Q37024399αT-catenin in restricted brain cell types and its potential connection to autism.

Search more.