Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development

scientific journal article

Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/DVDY.21803
P3181OpenCitations bibliographic resource ID3977746
P932PMC publication ID2639719
P698PubMed publication ID19035347
P5875ResearchGate publication ID23499160

P50authorA B FirulliQ68144966
Beth A FirulliQ88226782
Joshua W VincentzQ88576290
Simon J. ConwayQ92990872
Ralston M. BarnesQ123245469
P2860cites workMyocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cellsQ22008552
Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2CQ24307338
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactorsQ24314957
GATA-dependent recruitment of MEF2 proteins to target promotersQ24599616
Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2CQ24649105
The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of functionQ24657772
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locusQ24797230
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferationQ27863351
Embryonic retinoic acid synthesis is essential for early mouse post-implantation developmentQ28140751
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heartQ28190508
MEF2C transcription factor controls chondrocyte hypertrophy and bone developmentQ28505927
The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formationQ28513199
Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoproteinQ28578096
Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2CQ28589290
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5Q28590994
MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart fieldQ28591512
The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart developmentQ28592694
Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the splotch (Sp(2H))/Pax3 mouse mutantQ28594842
Genetic assembly of the heart: implications for congenital heart diseaseQ34142163
Transcription factors in cardiogenesis: the combinations that unlock the mysteries of the heartQ34562988
Developmental regulation of myosin gene expression in mouse cardiac muscleQ36224282
Csx: a murine homeobox-containing gene specifically expressed in the developing heartQ36513213
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardiumQ36561845
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.Q39945785
Molecular insights into cardiac developmentQ41748303
The outflow tract of the heart is recruited from a novel heart-forming fieldQ42819988
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart fieldQ46196456
Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndromeQ47955346
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesisQ48132703
Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte ViabilityQ57396510
Effects of retinoid deficiency on the development of the heart and vascular system of the quail embryoQ69876748
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendantsQ72678188
Conotruncal myocardium arises from a secondary heart fieldQ77102388
The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesodermQ77153201
Tumor formation in p53 mutant ovaries transplanted into wild-type female hostsQ80501621
Generation of conditional Mef2cloxP/loxP mice for temporal- and tissue-specific analysesQ81075221
P4510describes a project that usesImageJQ1659584
P433issue12
P921main subjectNK2 homeobox 5Q21984774
Myocyte enhancer factor 2CQ21985118
P304page(s)3809–3819
P577publication date2008-12-01
P1433published inDevelopmental DynamicsQ59752
P1476titleCooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development
P478volume237

Reverse relations

cites work (P2860)
Q35882673A Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis
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Q36545329Evolutionary conservation of Nkx2.5 autoregulation in the second heart field
Q37086538Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap.
Q35727809Exogenous Nkx2.5- or GATA-4-transfected rabbit bone marrow mesenchymal stem cells and myocardial cell co-culture on the treatment of myocardial infarction in rabbits
Q45909510Exogenous expression of homeoprotein EGAM1N prevents in vitro cardiomyogenesis by impairing expression of T and Nkx2.5, but not Mef2c, in mouse embryonic stem cells.
Q41850444Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells
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Q38180088Heart fields: spatial polarity and temporal dynamics
Q35752233Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling
Q33921337Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis
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Q64120396MEF-2 isoforms' (A-D) roles in development and tumorigenesis
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Q38084093Myocyte enhancer factor 2C in hematopoiesis and leukemia
Q36545299Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway.
Q37781313NKX2-5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD)
Q61797111Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation
Q41073528Porous, Ventricular Extracellular Matrix-Derived Foams as a Platform for Cardiac Cell Culture
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