PTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia

scientific article published on March 2011

PTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12032-011-9867-2
P8608Fatcat IDrelease_bslhot4korcfffyd2ogga7trgy
P698PubMed publication ID21360018

P2093author name stringCheng Zhiyong
Liang Wentong
Pan Ling
Yang Xiaoyang
P2860cites workVascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activationQ22004269
Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expressionQ23910931
Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cellsQ24300331
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesisQ24531835
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic nicheQ24600542
Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia.Q34327110
PI3K-Akt pathway: its functions and alterations in human cancerQ34362034
PTEN controls tumor-induced angiogenesisQ35282160
PI3K/PTEN signaling in tumorigenesis and angiogenesisQ36982971
AKT signaling in regulating angiogenesisQ37089915
Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cellsQ37116110
PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cellsQ39852386
PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes, CA9 and VEGF, in human cancer cell linesQ39864792
Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cellsQ40441841
PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartmentQ42163038
Quantification of VEGF isoforms and VEGFR transcripts by qRT-PCR and their significance in acute myeloid leukemiaQ47911803
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignanciesQ57591287
PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effectsQ64379300
Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated with poor clinical outcomeQ73701961
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenograftsQ80159172
A reappraisal by quantitative flow cytometry analysis of PTEN expression in acute leukemiaQ80568689
P433issue2
P921main subjectleukemiaQ29496
P304page(s)1084-1092
P577publication date2011-03-01
P1433published inMedical OncologyQ2152666
P1476titlePTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia
P478volume29

Reverse relations

cites work (P2860)
Q28384798Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells
Q43138991Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: a possible role for exosomal disposal of miR-21.
Q37137760Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish.
Q42011584PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
Q35585704VEGFR-1 overexpression identifies a small subgroup of aggressive prostate cancers in patients treated by prostatectomy

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