ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells.

scientific article published on March 2011

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/JCB.22996
P698PubMed publication ID21328461

P50authorJui-Hsiang HungQ40102296
P2093author name stringKung-Chia Young
Wen-Tsan Chang
Chiou-Feng Lin
Ih-Jen Su
Ming-Derg Lai
Huan-Yao Lei
Ya-Ting Chen
Yung-Sheng Chang
Wen-Ya Huang
Chien-An Huangfu
Chien-Ting Tsai
Pei-Huan Wu
P2860cites workER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cellsQ24300446
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinaseQ40524016
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Increased tumor necrosis factor alpha-converting enzyme activity induces insulin resistance and hepatosteatosis in mice.Q43251946
Polyunsaturated fatty acyl coenzyme A suppress the glucose-6-phosphatase promoter activity by modulating the DNA binding of hepatocyte nuclear factor 4 alpha.Q43895794
Glycogen synthase kinase-3beta mediates endoplasmic reticulum stress-induced lysosomal apoptosis in leukemia.Q45934477
Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitorQ46463465
Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4αQ59062103
Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7Q24306180
Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaQ24306430
Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PESTQ24307422
The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 associationQ24337866
Mammalian long-chain acyl-CoA synthetasesQ24602470
The gregarious lipid dropletQ24651460
Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulationQ24655658
Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failureQ28283926
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independentlyQ28574337
Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytesQ28580665
Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cellsQ28582601
Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decayQ31742604
Physiological and nutritional regulation of enzymes of triacylglycerol synthesisQ34001422
Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3betaQ34097322
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidationQ34512108
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expressionQ34563098
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stressesQ35169632
Differential regulation of STAT family members by glycogen synthase kinase-3Q36808508
A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulationQ36869495
Cell biology of lipid dropletsQ37209218
Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activityQ37431796
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid compositionQ37459831
Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connectionQ37739949
Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesisQ39846173
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylationQ40038649
The eIF2alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53.Q40085524
Involvement of ACSL in local synthesis of neutral lipids in cytoplasmic lipid droplets in human hepatocyte HuH7.Q40155357
Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivoQ40279185
Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcriptionQ40372631
Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes.Q40455477
P433issue3
P921main subjectendoplasmic reticulumQ79927
P304page(s)881-893
P577publication date2011-03-01
P1433published inJournal of Cellular BiochemistryQ6294917
P1476titleACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells
P478volume112

Reverse relations

cites work (P2860)
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