Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma

scientific article published on 14 January 2011

Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/CGT.2010.81
P698PubMed publication ID21233858
P5875ResearchGate publication ID49754348

P2093author name stringP Zhang
M Li
Y Li
J Zhou
Y Feng
Y Xie
J Xue
L Xiao
X Kong
S Cheng
G Yao
N Geng
P2860cites workExportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAsQ24302072
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assemblyQ24313436
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesisQ24323178
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNAQ24336971
The promises and pitfalls of RNA-interference-based therapeuticsQ24657247
The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expressionQ24797652
siRNAdb: a database of siRNA sequencesQ24797923
Inducible, reversible, and stable RNA interference in mammalian cellsQ36604113
Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cellsQ36854864
Strategies targeting telomerase inhibitionQ37067685
Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells.Q38329911
Telomerase reverse transcriptase (hTERT) mRNA and telomerase RNA (hTR) as targets for downregulation of telomerase activityQ38331538
Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activityQ39832411
VEGF- and LPA-induced telomerase in human ovarian cancer cells is Sp1-dependentQ40121812
Inhibition of telomerase RNA (hTR) in cervical cancer by adenovirus-delivered siRNA.Q40137267
Silencing of HIV-1 with RNA interference: a multiple shRNA approachQ40234514
Adenovirus-mediated small-interference RNA for in vivo silencing of angiotensin AT1a receptors in mouse brainQ40335621
Intensive inhibition of hTERT expression by a ribozyme induces rapid apoptosis of cancer cells through a telomere length-independent pathwayQ40365444
Target-specific gene silencing by siRNA plasmid DNA complexed with folate-modified poly(ethylenimine).Q40428170
An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhansQ40522098
Clinical significance and usefulness of quantification of telomerase activity in oral malignant and nonmalignant lesionsQ80507936
Increased expression of vascular endothelial growth factor C in papillary thyroid carcinoma correlates with cervical lymph node metastasesQ81506939
P433issue5
P304page(s)318-325
P577publication date2011-01-14
P1433published inCancer Gene TherapyQ15763088
P1476titleTelomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma
P478volume18

Reverse relations

cites work (P2860)
Q35125619Combinatorial gene targeting hTERT and BI-1 in CNE-2 nasopharyngeal carcinoma cell line
Q47829840MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.
Q28542909Silencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivo
Q37610098Targeting EBV-LMP1 DNAzyme enhances radiosensitivity of nasopharyngeal carcinoma cells by inhibiting telomerase activity
Q64885984Telomere Gene Therapy: Polarizing Therapeutic Goals for Treatment of Various Diseases.
Q47964963shRNA-mediated silencing of hTERT suppresses proliferation and promotes apoptosis in osteosarcoma cells

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