scholarly article | Q13442814 |
P50 | author | Steven E Artandi | Q91522987 |
P2093 | author name string | Michael P Terns | |
Rebecca M Terns | |||
Timothy D Veenstra | |||
Zhaojing Meng | |||
Andrew S Venteicher | |||
Eladio B Abreu | |||
Kelly E McCann | |||
P2860 | cites work | The many facets of H/ACA ribonucleoproteins | Q35038202 |
Dyskeratosis congenita: a genetic disorder of many faces | Q37001653 | ||
One-step affinity purification protocol for human telomerase | Q39724301 | ||
Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. | Q42057695 | ||
Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation | Q81340565 | ||
A telomerase component is defective in the human disease dyskeratosis congenita | Q22010917 | ||
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs | Q22121992 | ||
In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs | Q22253860 | ||
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase | Q24293589 | ||
The POT1-TPP1 telomere complex is a telomerase processivity factor | Q24293607 | ||
Functional conservation of the telomerase protein Est1p in humans | Q24299999 | ||
Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation | Q24303593 | ||
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly | Q24313436 | ||
hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase | Q24315010 | ||
Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres | Q24540232 | ||
Cell cycle-regulated trafficking of human telomerase to telomeres | Q24540240 | ||
Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10 | Q24551042 | ||
A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed | Q28116014 | ||
Protein composition of catalytically active human telomerase from immortal cells | Q28295708 | ||
Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing | Q28507063 | ||
NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria | Q28574203 | ||
The biogenesis and regulation of telomerase holoenzymes | Q34042917 | ||
Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells | Q34785598 | ||
P433 | issue | 5914 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Cajal body | Q3234345 |
positive regulation of telomerase activity | Q21104766 | ||
WD repeat containing antisense to TP53 | Q21125308 | ||
telomere-telomerase complex | Q22325241 | ||
P304 | page(s) | 644-8 | |
P577 | publication date | 2009-01-30 | |
P1433 | published in | Science | Q192864 |
P1476 | title | A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis | |
P478 | volume | 323 |
Q36436094 | 1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498. |
Q33718834 | 21st Century Genetics: Mass Spectrometry of Yeast Telomerase |
Q34592331 | A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis |
Q34154685 | A Cajal body-independent pathway for telomerase trafficking in mice |
Q38177591 | A Crowdsourced nucleus: understanding nuclear organization in terms of dynamically networked protein function. |
Q28238122 | A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles |
Q34957187 | A pathophysiological view of the long non-coding RNA world. |
Q37966835 | A role for sister telomere cohesion in telomere elongation by telomerase |
Q52668876 | A unique homozygous WRAP53 Arg298Trp mutation underlies dyskeratosis congenita in a Chinese Han family. |
Q34577015 | Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells |
Q64106291 | Alteration of 28S rRNA 2'--methylation by etoposide correlates with decreased SMN phosphorylation and reduced Drosha levels |
Q58766130 | Altered dynamics of scaRNA2 and scaRNA9 in response to stress correlates with disrupted nuclear organization |
Q88876109 | An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1 |
Q24336971 | An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA |
Q30921117 | An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance |
Q38801561 | An intact putative mouse telomerase essential N-terminal domain is necessary for proper telomere maintenance |
Q34208265 | Architecture of human telomerase RNA. |
Q38974934 | Assembly and trafficking of box C/D and H/ACA snoRNPs |
Q55306707 | Beginning at the ends: telomeres and human disease. |
Q92025204 | Biallelic mutations in WRAP53 result in dysfunctional telomeres, Cajal bodies and DNA repair, thereby causing Hoyeraal-Hreidarsson syndrome |
Q50286312 | Biogenesis and assembly of the telomerase RNP |
Q37913270 | Biogenesis of spliceosomal small nuclear ribonucleoproteins |
Q36246606 | Biogenesis of telomerase ribonucleoproteins |
Q36713390 | Cajal bodies are linked to genome conformation |
Q38050096 | Cajal bodies: where form meets function |
Q35391951 | Cajal body proteins differentially affect the processing of box C/D scaRNPs |
Q39045392 | Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase |
Q37825834 | Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene |
Q39776355 | Chromosomal and telomeric reprogramming following ES-somatic cell fusion. |
Q37706165 | Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis |
Q36597868 | Coilin displays differential affinity for specific RNAs in vivo and is linked to telomerase RNA biogenesis |
Q28084574 | Coilin: The first 25 years |
Q36532681 | Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner |
Q37692517 | Commonly used tag combinations for tandem affinity purification |
Q30459426 | Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase |
Q39176621 | Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres |
Q36612394 | Control of telomerase action at human telomeres |
Q52716589 | Cryo-EM structure of substrate-bound human telomerase holoenzyme. |
Q37741228 | Current Insights to Regulation and Role of Telomerase in Human Diseases. |
Q48023136 | Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites |
Q34670706 | Cytological maps of lampbrush chromosomes of European water frogs (Pelophylax esculentus complex) from the Eastern Ukraine. |
Q34935851 | Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita |
Q36793537 | Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs |
Q39734889 | Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability |
Q74441891 | Detailed view of human telomerase enzyme invites rethink of its structure |
Q64102415 | Determination of local chromatin interactions using a combined CRISPR and peroxidase APEX2 system |
Q30459320 | Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance |
Q34452324 | Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita |
Q52341702 | Distinct telomere length and molecular signatures in seminoma and non-seminoma of testicular germ cell tumor. |
Q39092025 | Diverse role of survival motor neuron protein |
Q36246404 | Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome |
Q38961879 | Dual roles of c-Myc in the regulation of hTERT gene |
Q36065063 | Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle |
Q36666256 | Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation |
Q50054621 | Dysfunctional telomeres and hematological disorders. |
Q35529338 | Dyskeratosis congenita as a disorder of telomere maintenance |
Q33558833 | Dyskerin ablation in mouse liver inhibits rRNA processing and cell division |
Q38694825 | Effect of Achillea wilhelmsii extract on expression of the human telomerase reverse transcriptase mRNA in the PC3 prostate cancer cell line |
Q27662381 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA |
Q58579018 | Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivity |
Q91622990 | Engineering a humanized telomerase reverse transcriptase gene in mouse embryonic stem cells |
Q33789662 | Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma |
Q37194197 | Evolutionary perspectives of telomerase RNA structure and function. |
Q34556782 | Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population-based GENICA study and external genetic databases |
Q91689860 | Expression of WDR79 is associated with TP53 mutation and poor prognosis in surgically resected non-small cell lung cancer |
Q28603241 | FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases |
Q37733004 | Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability |
Q24606549 | Finding the end: recruitment of telomerase to telomeres |
Q47276758 | Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder-Enriched Interactions |
Q37733930 | Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells |
Q34506827 | Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies |
Q37285981 | Genetic and environmental factors influencing human diseases with telomere dysfunction. |
Q38550343 | Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics. |
Q29617830 | Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions |
Q24293211 | HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment |
Q34560012 | Healthy aging and disease: role for telomere biology? |
Q92164033 | HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation |
Q90243303 | How RNAi machinery enters the world of telomerase |
Q26745549 | Human Specific Regulation of the Telomerase Reverse Transcriptase Gene |
Q36444298 | Human Telomerase Reverse Transcriptase (hTERT) Transcription Requires Sp1/Sp3 Binding to the Promoter and a Permissive Chromatin Environment |
Q34883221 | Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance |
Q42323459 | Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs. |
Q40568869 | Human intron-encoded AluACA RNAs and telomerase RNA share a common element promoting RNA accumulation |
Q28476202 | Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo |
Q41966984 | Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template |
Q30459660 | Human telomerase: biogenesis, trafficking, recruitment, and activation |
Q33851199 | Human telomeric proteins occupy selective interstitial sites |
Q51379477 | Identification of a subnuclear body involved in sequence-specific cytokine RNA processing. |
Q30459239 | Identification of human TERT elements necessary for telomerase recruitment to telomeres |
Q35392175 | Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing |
Q41385010 | Identification of processing elements and interactors implicate SMN, coilin and the pseudogene-encoded coilp1 in telomerase and box C/D scaRNP biogenesis |
Q28066490 | Implications of telomeres and telomerase in endometrial pathology |
Q34146318 | InTERTpreting telomerase structure and function |
Q34431404 | Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1. |
Q38070098 | Inherited bone marrow failure syndromes in 2012. |
Q29347523 | Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects |
Q30457044 | Inhibition of telomerase recruitment and cancer cell death |
Q26771437 | Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance |
Q51091931 | Introduction to Telomeres and Telomerase. |
Q30458501 | Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT. |
Q33717429 | Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants |
Q36676620 | Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles |
Q24337650 | Involvement of telomerase reverse transcriptase in heterochromatin maintenance |
Q26823394 | It all comes together at the ends: telomerase structure, function, and biogenesis |
Q50068202 | LARP7 family proteins have conserved function in telomerase assembly |
Q49538825 | LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast |
Q30460277 | Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres |
Q52984554 | Live-cell imaging of budding yeast telomerase RNA and TERRA. |
Q106089349 | Local Enrichment of HP1alpha at Telomeres Alters Their Structure and Regulation of Telomere Protection |
Q58765323 | Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection |
Q89548691 | Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation |
Q35667156 | Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation |
Q38818114 | Mammalian telomeres and their partnership with lamins. |
Q39587250 | Mapping the FEN1 interaction domain with hTERT. |
Q40976454 | Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies |
Q28083303 | Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering |
Q38637721 | Molecular basis of telomere dysfunction in human genetic diseases |
Q26741086 | Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks |
Q92735601 | N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation |
Q35823674 | Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin |
Q38875386 | New prospects for targeting telomerase beyond the telomere. |
Q28300721 | Novel small Cajal-body-specific RNAs identified in Drosophila: probing guide RNA function |
Q38006159 | Nuclear bodies: multifunctional companions of the genome |
Q35003162 | Nuclear bodies: random aggregates of sticky proteins or crucibles of macromolecular assembly? |
Q34043691 | On the road with WRAP53β: guardian of Cajal bodies and genome integrity |
Q58767113 | Oncogenic Activity of Wrap53 in Human Colorectal Cancer In Vitro and in Nude Mouse Xenografts |
Q37446726 | Overexpression of WDR79 in non-small cell lung cancer is linked to tumour progression |
Q42356676 | Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks |
Q36592599 | Pearls are novel Cajal body-like structures in the Xenopus germinal vesicle that are dependent on RNA pol III transcription |
Q39066545 | Peculiarities of Yeasts and Human Telomerase RNAs Processing |
Q37700947 | Phosphorylation and the Cajal body: modification in search of function |
Q36747492 | Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment |
Q41072533 | Phosphorylation of the Cajal body protein WRAP53β by ATM promotes its involvement in the DNA damage response |
Q36764309 | Phosphorylation regulates coilin activity and RNA association |
Q91735651 | Pistachio consumption modulates DNA oxidation and genes related to telomere maintenance: a crossover randomized clinical trial |
Q37619098 | Plasticity of telomere maintenance mechanisms in yeast |
Q29147385 | Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component |
Q38411937 | Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease. |
Q34987937 | Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA. |
Q24624897 | Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions |
Q39182224 | Progress in Human and Tetrahymena Telomerase Structure Determination |
Q27930896 | Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length |
Q24307986 | Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1 |
Q38989338 | RNA modification in Cajal bodies |
Q36717834 | RNA pseudouridylation: new insights into an old modification |
Q33480004 | Reduced viability, fertility and fecundity in mice lacking the cajal body marker protein, coilin. |
Q34271328 | Regulated assembly and disassembly of the yeast telomerase quaternary complex |
Q47138134 | Regulation of human and mouse telomerase genes by genomic contexts and transcription factors during embryonic stem cell differentiation |
Q91522991 | Regulation of human telomerase in homeostasis and disease |
Q36783452 | Replication of telomeres and the regulation of telomerase |
Q39111698 | Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes |
Q34017109 | Robust activation of the human but not mouse telomerase gene during the induction of pluripotency. |
Q26744271 | Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies |
Q41965772 | SMN and coilin negatively regulate dyskerin association with telomerase RNA. |
Q26852788 | Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy |
Q27003278 | Signals controlling Cajal body assembly and function |
Q39210046 | Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage |
Q30588428 | Single-molecule real-time detection of telomerase extension activity |
Q51800031 | Single-strand conformational polymorphism analysis of a common single nucleotide variation in WRAP53 gene, rs2287499, and evaluating its association in relation to breast cancer risk and prognosis among Iranian-Azeri population. |
Q24305098 | Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo |
Q42003187 | Structural Features of the Telomerase RNA Gene in the Naked Mole Rat Heterocephalus glaber |
Q36461908 | Structure and function of echinoderm telomerase RNA. |
Q28115347 | Structure of active dimeric human telomerase |
Q38095606 | Structure-function relationship and biogenesis regulation of the human telomerase holoenzyme |
Q37812407 | Structures of ribonucleoprotein particle modification enzymes. |
Q36544993 | Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells |
Q21245751 | TCAB1: a potential target for diagnosis and therapy of head and neck carcinomas |
Q35067743 | TIN2 protein dyskeratosis congenita missense mutants are defective in association with telomerase |
Q24606587 | TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo |
Q35781400 | TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome |
Q38322972 | TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends |
Q98177214 | Targeting telomerase for cancer therapy |
Q37750789 | Targeting telomerase in hematologic malignancy |
Q33698657 | Targeting vertebrate intron-encoded box C/D 2'-O-methylation guide RNAs into the Cajal body. |
Q33967373 | Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G1 cell cycle arrest in A549 cells |
Q39111969 | Telomerase Mechanism of Telomere Synthesis |
Q50086340 | Telomerase RNA Imaging in Budding Yeast and Human Cells by Fluorescent In Situ Hybridization |
Q28075938 | Telomerase Regulation from Beginning to the End |
Q52883665 | Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. |
Q28085343 | Telomerase activity and telomere length in male germ cells |
Q64911093 | Telomerase and Telomeres in Endometrial Cancer. |
Q35651418 | Telomerase and retrotransposons: reverse transcriptases that shaped genomes |
Q37975743 | Telomerase and telomere-associated proteins: structural insights into mechanism and evolution |
Q43444556 | Telomerase gene mutations are associated with cirrhosis formation |
Q39608072 | Telomerase inhibition strategies by siRNAs against either hTR or hTERT in oral squamous cell carcinoma |
Q36210861 | Telomerase recruitment requires both TCAB1 and Cajal bodies independently |
Q37950142 | Telomerase regulation |
Q33951245 | Telomerase trafficking and assembly in Xenopus oocytes |
Q26739948 | Telomerase: The Devil Inside |
Q37775786 | Telomerase: an RNP enzyme synthesizes DNA. |
Q38587987 | Telomere Dysfunction, Chromosomal Instability and Cancer. |
Q26744808 | Telomere and Telomerase Therapeutics in Cancer |
Q38707524 | Telomere dynamics in dyskeratosis congenita: the long and the short of iPS. |
Q35563251 | Telomere dynamics in induced pluripotent stem cells: Potentials for human disease modeling |
Q37885748 | Telomere dysfunction in human bone marrow failure syndromes |
Q37293044 | Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase. |
Q38032836 | Telomere lengthening and other functions of telomerase. |
Q34426966 | Telomere maintenance mechanisms in cancer: clinical implications |
Q24617599 | Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells |
Q34784471 | Telomere-regulating genes and the telomere interactome in familial cancers. |
Q89976278 | Telomeres and Telomere Length: A General Overview |
Q26747735 | Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases |
Q37627017 | Telomeres and telomerase in cancer |
Q37834658 | Telomeres as targets for anticancer therapies. |
Q34310430 | Telomeres at a glance. |
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Q33740892 | Telomeres: protecting chromosomes against genome instability |
Q37419279 | Telomeric armor: the layers of end protection |
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Q42152999 | The regulation of telomerase in oncogenesis. |
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Q38035437 | The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems |
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Q38797923 | Towards an understanding of regulating Cajal body activity by protein modification |
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Q38115589 | Updates on the biology and management of dyskeratosis congenita and related telomere biology disorders |
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Q37175957 | Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination |
Q40475025 | mRNA accumulation in the Cajal bodies of the diplotene larch microsporocyte. |
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