SMN and coilin negatively regulate dyskerin association with telomerase RNA.

scientific article published on 23 May 2016

SMN and coilin negatively regulate dyskerin association with telomerase RNA. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/BIO.018804
P932PMC publication ID4920197
P698PubMed publication ID27215323

P50authorMichael D HebertQ90425949
P2093author name stringAaron R Poole
P2860cites workWRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodiesQ21145787
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesisQ24316121
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesisQ24323178
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodiesQ24336921
Self-association of coilin reveals a common theme in nuclear body localizationQ24551044
Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy proteinQ24600358
Structure, expression and chromosomal localization of human p80-coilin geneQ24605102
Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNPQ24647530
The SMN complex, an assemblyosome of ribonucleoproteinsQ28204829
The coilin interactome identifies hundreds of small noncoding RNAs that traffic through Cajal bodies.Q51502949
Classification of spinal muscular atrophiesQ72423037
SMN oligomerization defect correlates with spinal muscular atrophy severityQ74557706
Solution structure of the carboxy-terminal Tudor domain from human CoilinQ85102498
Coilin methylation regulates nuclear body formationQ28205265
The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1Q28213183
A conserved WD40 protein binds the Cajal body localization signal of scaRNP particlesQ28238122
SMN-mediated assembly of RNPs: a complex storyQ28678650
SMN in spinal muscular atrophy and snRNP biogenesisQ29013847
Coilin phosphomutants disrupt Cajal body formation, reduce cell proliferation and produce a distinct coilin degradation productQ31032498
Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?Q33785933
The product of the survival of motor neuron (SMN) gene is a human telomerase-associated proteinQ34060945
In vitro RNase and nucleic acid binding activities implicate coilin in U snRNA processingQ34257423
Essential role for the SMN complex in the specificity of snRNP assemblyQ34529450
Carrier testing for spinal muscular atrophyQ34778760
Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenanceQ34883221
SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins.Q35641208
Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferationQ36142454
Telomerase recruitment requires both TCAB1 and Cajal bodies independentlyQ36210861
Biogenesis of telomerase ribonucleoproteinsQ36246606
Regulated specific proteolysis of the Cajal body marker protein coilinQ36460273
Coilin displays differential affinity for specific RNAs in vivo and is linked to telomerase RNA biogenesisQ36597868
Phosphorylation regulates coilin activity and RNA associationQ36764309
Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesisQ37706165
Cajal bodies: where form meets functionQ38050096
SMA-causing missense mutations in survival motor neuron (Smn) display a wide range of phenotypes when modeled in Drosophila.Q41835189
The domain encoded by exon 2 of the survival motor neuron protein mediates nucleic acid binding.Q47827629
The RNA-binding properties of SMN: deletion analysis of the zebrafish orthologue defines domains conserved in evolutionQ47973518
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue6
P304page(s)726-735
P577publication date2016-05-23
P1433published inBiology OpenQ27724268
P1476titleSMN and coilin negatively regulate dyskerin association with telomerase RNA.
P478volume5

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cites work (P2860)
Q50052600Advances in therapy for spinal muscular atrophy: promises and challenges.
Q58766130Altered dynamics of scaRNA2 and scaRNA9 in response to stress correlates with disrupted nuclear organization
Q30274553Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.
Q39092025Diverse role of survival motor neuron protein
Q104567661Pathogenesis and therapeutic targets in spinal muscular atrophy (SMA)
Q38624976Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity
Q28075938Telomerase Regulation from Beginning to the End
Q93082066The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications
Q64444095The role of survival motor neuron protein (SMN) in protein homeostasis
Q38797923Towards an understanding of regulating Cajal body activity by protein modification

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