RNA pseudouridylation: new insights into an old modification

scientific article published on 4 February 2013

RNA pseudouridylation: new insights into an old modification is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TIBS.2013.01.002
P932PMC publication ID3608706
P698PubMed publication ID23391857

P2093author name stringYi-Tao Yu
Junhui Ge
P2860cites workNhp2p and Nop10p are essential for the function of H/ACA snoRNPsQ22008508
X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functionsQ24317067
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesisQ24323178
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAsQ24530279
Nucleolar localization signals of box H/ACA small nucleolar RNAsQ24534435
A small nucleolar guide RNA functions both in 2'-O-ribose methylation and pseudouridylation of the U5 spliceosomal RNAQ24536377
A computational screen for mammalian pseudouridylation guide H/ACA RNAsQ24537497
A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architectureQ24540031
Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genomeQ24563506
Reconstitution of archaeal H/ACA small ribonucleoprotein complexes active in pseudouridylationQ24810243
Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activityQ25257185
Pseudouridines in spliceosomal snRNAsQ26865050
Sculpting of the spliceosomal branch site recognition motif by a conserved pseudouridineQ27639938
H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modificationQ27644371
Solution structure of an rRNA substrate bound to the pseudouridylation pocket of a box H/ACA snoRNAQ27644631
Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complexQ27649214
X-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Q27650449
Crystal structure of a translation termination complex formed with release factor RF2Q27653093
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNAQ27655679
Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthaseQ27655688
Pseudouridylation (Psi) of U2 snRNA in S. cerevisiae is catalyzed by an RNA-independent mechanismQ27934006
The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthaseQ27935785
Accumulation of H/ACA snoRNPs depends on the integrity of the conserved central domain of the RNA-binding protein Nhp2p.Q27936087
Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanismQ27936751
Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.Q27937578
The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAsQ27938085
Pseudouridine in RNA: what, where, how, and whyQ28141248
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tRNA transfers to the limelightQ28203809
A conserved WD40 protein binds the Cajal body localization signal of scaRNP particlesQ28238122
Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAsQ28240607
The numerous modified nucleotides in eukaryotic ribosomal RNAQ28263677
The RNA Modification Database, RNAMDB: 2011 updateQ28298150
rRNA modifications and ribosome functionQ28610126
Compilation of tRNA sequences and sequences of tRNA genesQ29615891
The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functionsQ29616485
Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNAQ29618482
Investigation of Overhauser effects between pseudouridine and water protons in RNA helicesQ30724468
RNA-guided RNA modification: functional organization of the archaeal H/ACA RNPQ33826941
A small nucleolar RNP protein is required for pseudouridylation of eukaryotic ribosomal RNAsQ33887226
Elements essential for accumulation and function of small nucleolar RNAs directing site-specific pseudouridylation of ribosomal RNAsQ33890338
Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNAQ33959977
Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1Q33960716
MODOMICS: a database of RNA modification pathways. 2008 updateQ34014085
A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivoQ34119811
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activationQ34146278
Pseudouridylation goes regulatoryQ34157560
Functions and mechanisms of spliceosomal small nuclear RNA pseudouridylationQ34169607
Ribosome structure and activity are altered in cells lacking snoRNPs that form pseudouridines in the peptidyl transferase centerQ34181714
Converting nonsense codons into sense codons by targeted pseudouridylationQ34192969
An H/ACA guide RNA directs U2 pseudouridylation at two different sites in the branchpoint recognition region in Xenopus oocytes.Q34364873
Characterization of the catalytic activity of U2 and U6 snRNAsQ34365232
Pseudouridines in and near the branch site recognition region of U2 snRNA are required for snRNP biogenesis and pre-mRNA splicing in Xenopus oocytesQ34365658
U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP.Q34485772
RNomics: identification and function of small, non-messenger RNAsQ35019396
rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.Q35569577
Primary and secondary structures of Escherichia coli MRE 600 23S ribosomal RNA. Comparison with models of secondary structure for maize chloroplast 23S rRNA and for large portions of mouse and human 16S mitochondrial rRNAsQ35741926
Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA featuresQ35775765
Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietinQ35939486
Box H and box ACA are nucleolar localization elements of U17 small nucleolar RNA.Q36939903
Functionality and substrate specificity of human box H/ACA guide RNAsQ37034276
Pathogenic NAP57 mutations decrease ribonucleoprotein assembly in dyskeratosis congenitaQ37411787
Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stabilityQ37416925
Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracyQ37477549
The presence of pseudouridine in the anticodon alters the genetic code: a possible mechanism for assignment of the AAA lysine codon as asparagine in echinoderm mitochondria.Q39727686
A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs.Q39831945
Stabilization of RNA stacking by pseudouridineQ40397122
Ribosome performance is enhanced by a rich cluster of pseudouridines in the A-site finger region of the large subunitQ40420065
A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast.Q41355883
Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons.Q41509910
A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomicsQ42180595
Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.Q42323459
The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.Q42486419
Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processingQ42554055
Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicingQ42656253
Psi35 in the branch site recognition region of U2 small nuclear RNA is important for pre-mRNA splicing in Saccharomyces cerevisiaeQ45195748
Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.Q46904259
Increased urinary level of oxidized nucleosides in patients with mild-to-moderate Alzheimer's disease.Q53388119
Crystal structure of an H/ACA box ribonucleoprotein particle.Q53589609
Posttranscriptionally modified nucleosides in transfer RNA: their locations and frequenciesQ71699636
More Sm snRNAs from vertebrate cellsQ71952622
Crystal structure of unmodified tRNA(Gln) complexed with glutaminyl-tRNA synthetase and ATP suggests a possible role for pseudo-uridines in stabilization of RNA structureQ72015576
Ribonucleic acids from yeast which contain a fifth nucleotideQ74610888
rRNA modifications in an intersubunit bridge of the ribosome strongly affect both ribosome biogenesis and activityQ80407834
P433issue4
P1104number of pages9
P304page(s)210-218
P577publication date2013-02-04
P1433published inTrends in Biochemical SciencesQ1565711
P1476titleRNA pseudouridylation: new insights into an old modification
P478volume38

Reverse relations

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